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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Study finds senescent immune cells promote lung tumor growth

Study finds senescent immune cells promote lung tumor growth

by Mayo ClinicGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.006Macrophages are a type of white blood cell that are among the body's first line of defe

Study finds senescent immune cells promote lung tumor growth

by Mayo ClinicGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.006Macrophages are a type of white blood cell that are among the body's first line of defe
New model could reduce reliance on chemotherapy

New model could reduce reliance on chemotherapy

byAnglia Ruskin UniversityCredit: Unsplash/CC0 Public DomainA model co-designed by a professor at Anglia Ruskin University is expected to reduce the need for chemotherapy in up to 38% of breast

New model could reduce reliance on chemotherapy

byAnglia Ruskin UniversityCredit: Unsplash/CC0 Public DomainA model co-designed by a professor at Anglia Ruskin University is expected to reduce the need for chemotherapy in up to 38% of breast
Genomic features of AML in patients over age 60 can predict success of stem cell transplant

Genomic features of AML in patients over age 60 can predict success of stem cell transplant

by Dana-Farber Cancer InstituteR. Coleman Lindsley, MD, PhD. Credit: Dana-Farber Cancer InstituteFor older patients with acute myeloid leukemia (AML), the prospects for success of a stem cell tra

Genomic features of AML in patients over age 60 can predict success of stem cell transplant

by Dana-Farber Cancer InstituteR. Coleman Lindsley, MD, PhD. Credit: Dana-Farber Cancer InstituteFor older patients with acute myeloid leukemia (AML), the prospects for success of a stem cell tra
Biology behind new drug used to treat triple-negative breast cancer uncovered

Biology behind new drug used to treat triple-negative breast cancer uncovered

by Georgetown University Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainHow TTP488 (azeliragon), an experimental drug, impairs aggr

Biology behind new drug used to treat triple-negative breast cancer uncovered

by Georgetown University Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainHow TTP488 (azeliragon), an experimental drug, impairs aggr
AI's ability to detect tumor cells could be key to more accurate bone cancer prognoses

AI's ability to detect tumor cells could be key to more accurate bone cancer prognoses

byKyushu UniversityResearchers from Kyushu University, Japan have developed a novel deep-learning model which can accurately estimate viable tumor cell density from pathological images of osteos

AI's ability to detect tumor cells could be key to more accurate bone cancer prognoses

byKyushu UniversityResearchers from Kyushu University, Japan have developed a novel deep-learning model which can accurately estimate viable tumor cell density from pathological images of osteos
Biochemists, cancer biologists find key vulnerability in rare brain tumors

Biochemists, cancer biologists find key vulnerability in rare brain tumors

by Anne Manning,Colorado State UniversityCredit: Pixabay/CC0 Public DomainSince the start of her career, Jennifer DeLuca has been fascinated by mitosis, the everyday biological process of cell d

Biochemists, cancer biologists find key vulnerability in rare brain tumors

by Anne Manning,Colorado State UniversityCredit: Pixabay/CC0 Public DomainSince the start of her career, Jennifer DeLuca has been fascinated by mitosis, the everyday biological process of cell d
New research discovers new cause of cancer coming from inside us

New research discovers new cause of cancer coming from inside us

byFlinders UniversityHusband and wife Professor Simon Conn and Dr Vanessa Conn’s team at the Flinders Centre for Innovation in Cancer has been researching the role of circular RNAs in DNA damage

New research discovers new cause of cancer coming from inside us

byFlinders UniversityHusband and wife Professor Simon Conn and Dr Vanessa Conn’s team at the Flinders Centre for Innovation in Cancer has been researching the role of circular RNAs in DNA damage
Using single-cell sequencing to reveal processes involved in ovarian and breast cancers

Using single-cell sequencing to reveal processes involved in ovarian and breast cancers

by Bob Yirka , Medical XpressStudy overview. Experimental and cohort design. Single-cell genomes, transcriptomes and long-read sequencing libraries were generated from isogenic 184-hTERT cell lines (W

Using single-cell sequencing to reveal processes involved in ovarian and breast cancers

by Bob Yirka , Medical XpressStudy overview. Experimental and cohort design. Single-cell genomes, transcriptomes and long-read sequencing libraries were generated from isogenic 184-hTERT cell lines (W
Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m

Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m
A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya
Telerehabilitation aids function, pain with advanced cancer

Telerehabilitation aids function, pain with advanced cancer

(HealthDay)—Collaborative telerehabilitation modestly improves function and pain while decreasing hospital length of stay and the need for postacute care in advanced cancer patients, according to a st

Telerehabilitation aids function, pain with advanced cancer

(HealthDay)—Collaborative telerehabilitation modestly improves function and pain while decreasing hospital length of stay and the need for postacute care in advanced cancer patients, according to a st
New model predicts 10-year breast cancer risk

New model predicts 10-year breast cancer risk

byUniversity of OxfordSmoothed calibration plots of the alignment between predicted and observed risks for each of the models The red lines correspond to the calibration curve, with the red shad

New model predicts 10-year breast cancer risk

byUniversity of OxfordSmoothed calibration plots of the alignment between predicted and observed risks for each of the models The red lines correspond to the calibration curve, with the red shad