Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on: January 26,2024

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on:January 26,2024

Blood cancer research points to new treatment for bone marrow cancer

byUniversity of VirginiaDeletion of IL-1R1 preferentially inhibits Jak2V617F mutant hematopoietic stem/progenitor cells.aA scheme on competitive BM transplantation approach to assess

Updated on: January 15,2024

Blood cancer research points to new treatment for bone marrow cancer

byUniversity of VirginiaDeletion of IL-1R1 preferentially inhibits Jak2V617F mutant hematopoietic stem/progenitor cells.aA scheme on competitive BM transplantation approach to assess

Updated on:January 15,2024

Neoantigen DNA Vaccines: A Promising Approach for Triple Negative Breast Cancer

Among innovative strategies, neoantigen DNA vaccines have emerged as a particularly promising approach, offering hope for improved patient outcomes.

Updated on: November 15,2024

Neoantigen DNA Vaccines: A Promising Approach for Triple Negative Breast Cancer

Among innovative strategies, neoantigen DNA vaccines have emerged as a particularly promising approach, offering hope for improved patient outcomes.

Updated on:November 15,2024

Researchers: Favorable survival, fewer side effects after reduced therapy for HPV-linked head and neck cancer

by University of North Carolina at Chapel Hill School of MedicineBhisham Chera, MD. Credit: University of North Carolina at Chapel Hill School of MedicineUniversity of North Carolina Lineberger C

Updated on: March 01,2024

Researchers: Favorable survival, fewer side effects after reduced therapy for HPV-linked head and neck cancer

by University of North Carolina at Chapel Hill School of MedicineBhisham Chera, MD. Credit: University of North Carolina at Chapel Hill School of MedicineUniversity of North Carolina Lineberger C

Updated on:March 01,2024

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on: July 09,2024

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on:July 09,2024

Treatment strategies for adenoid cystic carcinoma of the head and neck

by Impact Journals LLCCT-scan in a coronal section showing an adenoid cystic carcinoma as an inhomogeneous mass in the rightmaxillary sinus with infiltration of neighboring structures. Credit: 2023 Du

Updated on: January 07,2024

Treatment strategies for adenoid cystic carcinoma of the head and neck

by Impact Journals LLCCT-scan in a coronal section showing an adenoid cystic carcinoma as an inhomogeneous mass in the rightmaxillary sinus with infiltration of neighboring structures. Credit: 2023 Du

Updated on:January 07,2024

Pancreatic cancer tumor map uncovers notable differences between primary and metastatic disease

by Candace Gwaltney,Indiana UniversityIdentification of pancreatic cancer architecture. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01914-4Indiana University Melvin and Bre

Updated on: November 11,2024

Pancreatic cancer tumor map uncovers notable differences between primary and metastatic disease

by Candace Gwaltney,Indiana UniversityIdentification of pancreatic cancer architecture. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01914-4Indiana University Melvin and Bre

Updated on:November 11,2024

Fighting cancer with LIGHT, a novel proton accelerator for treatment

by Kristiane Bernhard-Novotny,CERNModel of the LIGHT accelerator, including treatment room. Credit: AVOCancer irradiation with hadron beams, a method to which CERN contributed by propelling carb

Updated on: January 29,2024

Fighting cancer with LIGHT, a novel proton accelerator for treatment

by Kristiane Bernhard-Novotny,CERNModel of the LIGHT accelerator, including treatment room. Credit: AVOCancer irradiation with hadron beams, a method to which CERN contributed by propelling carb

Updated on:January 29,2024

Severe mental illness linked to low attendance at cancer screening

byUniversity of SurreyCredit: CC0 Public DomainPeople with severe mental illness are less likely to attend cancer screening compared to those who do not have such conditions, according to new re

Updated on: January 22,2024

Severe mental illness linked to low attendance at cancer screening

byUniversity of SurreyCredit: CC0 Public DomainPeople with severe mental illness are less likely to attend cancer screening compared to those who do not have such conditions, according to new re

Updated on:January 22,2024

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on: January 10,2024

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on:January 10,2024

Researchers discover novel way to make breast cancer cells die

by Steve Lundeberg,Oregon State UniversityCredit:ACS Pharmacology & Translational Science(2024). DOI: 10.1021/acsptsci.3c00360Oregon State University researchers have discovered

Updated on: July 08,2024

Researchers discover novel way to make breast cancer cells die

by Steve Lundeberg,Oregon State UniversityCredit:ACS Pharmacology & Translational Science(2024). DOI: 10.1021/acsptsci.3c00360Oregon State University researchers have discovered

Updated on:July 08,2024

12.8 percent of unique prescribers prescribed topical antifungals in 2021

by Elana GotkineIn 2021, 12.8 percent of unique prescribers in Medicare Part D prescribed topical antifungals, with about 6.5 million topical antifungal prescriptions filled, at a total cost of $231 m

Updated on: March 22,2024

12.8 percent of unique prescribers prescribed topical antifungals in 2021

by Elana GotkineIn 2021, 12.8 percent of unique prescribers in Medicare Part D prescribed topical antifungals, with about 6.5 million topical antifungal prescriptions filled, at a total cost of $231 m

Updated on:March 22,2024