Study finds carcinogen exposure makes cancer cells more susceptible to immune attack

by Liz Murphy,Massachusetts General HospitalCarcinogen-exposed cancer cells transform that nature of tumor-infiltrating macrophages from immunosuppressive (left) to immune activating agents (rig

Updated on: October 31,2023

Study finds carcinogen exposure makes cancer cells more susceptible to immune attack

by Liz Murphy,Massachusetts General HospitalCarcinogen-exposed cancer cells transform that nature of tumor-infiltrating macrophages from immunosuppressive (left) to immune activating agents (rig

Updated on:October 31,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on: October 11,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on:October 11,2023

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28

Updated on: May 11,2024

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28

Updated on:May 11,2024

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on: October 11,2023

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on:October 11,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MD Prithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal t

Updated on: October 10,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MD Prithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal t

Updated on:October 10,2023

Immunotherapy for Cancer: What Are My Options?

ByJennifer WelshPublished on September 06, 2023Medically reviewed byDoru Paul, MDImmunotherapy is a relatively new approach to cancer treatment. It improves the body's immu

Updated on: November 20,2023

Immunotherapy for Cancer: What Are My Options?

ByJennifer WelshPublished on September 06, 2023Medically reviewed byDoru Paul, MDImmunotherapy is a relatively new approach to cancer treatment. It improves the body's immu

Updated on:November 20,2023

To stop spread of cancer, researchers target two signaling switches that trigger new blood vessel growth

byUniversity of East AngliaCredit: Unsplash/CC0 Public DomainHitting two targets at the same time may be the key to stopping the spread of aggressive cancers, according to new research from the

Updated on: January 08,2024

To stop spread of cancer, researchers target two signaling switches that trigger new blood vessel growth

byUniversity of East AngliaCredit: Unsplash/CC0 Public DomainHitting two targets at the same time may be the key to stopping the spread of aggressive cancers, according to new research from the

Updated on:January 08,2024

Single set of criteria to assess progression in glioma aims to speed discovery of new medicines

byDana-Farber Cancer InstituteInfant high-grade glioma. Credit: David Ellison, St. Jude Children’s Research HospitalIn order to accurately assess the efficacy of novel therapies for brain tumors

Updated on: October 31,2023

Single set of criteria to assess progression in glioma aims to speed discovery of new medicines

byDana-Farber Cancer InstituteInfant high-grade glioma. Credit: David Ellison, St. Jude Children’s Research HospitalIn order to accurately assess the efficacy of novel therapies for brain tumors

Updated on:October 31,2023

Liver cancer: Risk factors and prevention

by Laurel Kelly,Mayo ClinicCredit: Pixabay/CC0 Public DomainOctober is Liver Cancer Awareness Month, which makes this a good time to learn more about risk factors for liver cancer and what you c

Updated on: October 31,2023

Liver cancer: Risk factors and prevention

by Laurel Kelly,Mayo ClinicCredit: Pixabay/CC0 Public DomainOctober is Liver Cancer Awareness Month, which makes this a good time to learn more about risk factors for liver cancer and what you c

Updated on:October 31,2023

New potential therapeutic approach for HER2-positive breast cancer discovered

by Leibniz Research Centre for Working Environments and Human Factors in DortmundEDI3 expression and enzyme activity according to HER2 and ER status. A, EDI3 (GPCPD1; 224826_at) mRNA expression was co

Updated on: December 21,2023

New potential therapeutic approach for HER2-positive breast cancer discovered

by Leibniz Research Centre for Working Environments and Human Factors in DortmundEDI3 expression and enzyme activity according to HER2 and ER status. A, EDI3 (GPCPD1; 224826_at) mRNA expression was co

Updated on:December 21,2023

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on: January 08,2024

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on:January 08,2024

Gene linked to glioblastoma stem cell self-renewal and immunosuppression

by Olivia Dimmer,Northwestern UniversityWorking model. a, Illustration shows a proposed mechanism for the TFPI2 and its associated signaling axis in regulating self-renewal of glioma stem cells

Updated on: October 31,2023

Gene linked to glioblastoma stem cell self-renewal and immunosuppression

by Olivia Dimmer,Northwestern UniversityWorking model. a, Illustration shows a proposed mechanism for the TFPI2 and its associated signaling axis in regulating self-renewal of glioma stem cells

Updated on:October 31,2023