Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on: March 30,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on:March 30,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on: January 22,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on:January 22,2024

Metastatic cancer gorges on fructose in the liver

by Duke UniversityCredit: CC0 Public DomainBiomedical engineers at Duke University have demonstrated that metastatic cancer cells can reprogram their metabolism to thrive in new organs. Specifica

Updated on: April 01,2024

Metastatic cancer gorges on fructose in the liver

by Duke UniversityCredit: CC0 Public DomainBiomedical engineers at Duke University have demonstrated that metastatic cancer cells can reprogram their metabolism to thrive in new organs. Specifica

Updated on:April 01,2024

Prediagnosis exercise may reduce CV risk in breast cancer

(HealthDay)—For women with primary breast cancer, prediagnosis exercise exposure is associated with a graded reduction in subsequent cardiovascular event (CVE) risk, according to a study published in

Updated on: April 14,2024

Prediagnosis exercise may reduce CV risk in breast cancer

(HealthDay)—For women with primary breast cancer, prediagnosis exercise exposure is associated with a graded reduction in subsequent cardiovascular event (CVE) risk, according to a study published in

Updated on:April 14,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on: March 01,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on:March 01,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on: June 06,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on:June 06,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on: April 22,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on:April 22,2024

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic

Updated on: April 22,2024

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic

Updated on:April 22,2024

Researchers find superantigen mutant can trigger immune response in ovarian cancer cells

by Liu Jia,Chinese Academy of SciencesThe transwell co-culture models of transcriptome experiment. Credit:International Journal of Molecular Sciences(2023). DOI: 10.3390/ijms24141179

Updated on: January 30,2024

Researchers find superantigen mutant can trigger immune response in ovarian cancer cells

by Liu Jia,Chinese Academy of SciencesThe transwell co-culture models of transcriptome experiment. Credit:International Journal of Molecular Sciences(2023). DOI: 10.3390/ijms24141179

Updated on:January 30,2024

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on: February 18,2024

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on:February 18,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on: February 03,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on:February 03,2024