Study finds 'startling' inequities in end-of-life opioid treatment

byHarvard UniversityCredit: Unsplash/CC0 Public DomainOlder Black and Hispanic patients with advanced cancer are less likely than white patients to receive opioid medications for pain relief in

Updated on: January 23,2024

Study finds 'startling' inequities in end-of-life opioid treatment

byHarvard UniversityCredit: Unsplash/CC0 Public DomainOlder Black and Hispanic patients with advanced cancer are less likely than white patients to receive opioid medications for pain relief in

Updated on:January 23,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on: August 03,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on:August 03,2024

Oncology trial shows positive results for patients with muscle-invasive urothelial carcinoma

JANUARY 26, 2024by Alliance for Clinical Trials in OncologyCredit: Pixabay/CC0 Public DomainPatients with muscle-invasive urothelial cancer and a high risk of recurrence after surgery may have a new t

Updated on: March 30,2024

Oncology trial shows positive results for patients with muscle-invasive urothelial carcinoma

JANUARY 26, 2024by Alliance for Clinical Trials in OncologyCredit: Pixabay/CC0 Public DomainPatients with muscle-invasive urothelial cancer and a high risk of recurrence after surgery may have a new t

Updated on:March 30,2024

Mouse studies have revealed more about the mechanisms behind cancer drugs in trials

by Agency for Science, Technology and Research (A*STAR), SingaporeDNA damage (red) in the spleen of a mouse that expresses the mutant form of CDK1 that cannot be suppressed by phosphorylation. Cr

Updated on: March 01,2024

Mouse studies have revealed more about the mechanisms behind cancer drugs in trials

by Agency for Science, Technology and Research (A*STAR), SingaporeDNA damage (red) in the spleen of a mouse that expresses the mutant form of CDK1 that cannot be suppressed by phosphorylation. Cr

Updated on:March 01,2024

Researchers create novel compound targeting melanoma cells

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0An international team of re

Updated on: June 24,2024

Researchers create novel compound targeting melanoma cells

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0An international team of re

Updated on:June 24,2024

New details revealed to explain how tumors recruit blood vessels

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainA study by University of North Carolina Lineberger Comprehensive Cancer Center researchers helps explain

Updated on: March 12,2024

New details revealed to explain how tumors recruit blood vessels

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainA study by University of North Carolina Lineberger Comprehensive Cancer Center researchers helps explain

Updated on:March 12,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on: March 12,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on:March 12,2024

A new drug prevents epithelial-mesenchymal transition, metastasis and resistance to anti-cancer therapy

by Université libre de BruxellesTargeting netrin-1 reduces metastasis and sensitizes tumor cells to chemotherapy in skin SCC.a, Dot plot showing the number of spontaneous lung metastases in

Updated on: January 30,2024

A new drug prevents epithelial-mesenchymal transition, metastasis and resistance to anti-cancer therapy

by Université libre de BruxellesTargeting netrin-1 reduces metastasis and sensitizes tumor cells to chemotherapy in skin SCC.a, Dot plot showing the number of spontaneous lung metastases in

Updated on:January 30,2024

Study supports links between bovine meat and milk factor protein expression, inflammation as cause of colorectal cancer

by WileyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Bovine meat and milk factors (BMMFs)—initially identified by de Villiers et al. in 2014—represent a class

Updated on: February 18,2024

Study supports links between bovine meat and milk factor protein expression, inflammation as cause of colorectal cancer

by WileyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Bovine meat and milk factors (BMMFs)—initially identified by de Villiers et al. in 2014—represent a class

Updated on:February 18,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on: May 13,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on:May 13,2024

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on: February 18,2024

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on:February 18,2024

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga

Updated on: February 03,2024

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga

Updated on:February 03,2024