Targeting mutation slows breast cancer spread, study finds

Credit: Pixabay/CC0 Public DomainThe progression of certain types of breast cancers can be slowed by identifying a particular genetic mutation and then quickly adapting treatment, a first-of-its-kind

Updated on: January 23,2024

Targeting mutation slows breast cancer spread, study finds

Credit: Pixabay/CC0 Public DomainThe progression of certain types of breast cancers can be slowed by identifying a particular genetic mutation and then quickly adapting treatment, a first-of-its-kind

Updated on:January 23,2024

Existing cancer drugs have potential to benefit thousands more patients, research shows

byInstitute of Cancer ResearchSF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Credit:Nature Genetics(2023). DOI: 1

Updated on: January 16,2024

Existing cancer drugs have potential to benefit thousands more patients, research shows

byInstitute of Cancer ResearchSF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Credit:Nature Genetics(2023). DOI: 1

Updated on:January 16,2024

Researchers discover a mechanism that controls the identity of stem cells

by University of California, IrvineCredit:Molecular Cell(2023). DOI: 10.1016/j.molcel.2023.10.036Researchers at the University of California, Irvine, discovered a mechanism that contr

Updated on: February 03,2024

Researchers discover a mechanism that controls the identity of stem cells

by University of California, IrvineCredit:Molecular Cell(2023). DOI: 10.1016/j.molcel.2023.10.036Researchers at the University of California, Irvine, discovered a mechanism that contr

Updated on:February 03,2024

Researchers identify novel gene networks associated with aggressive type of breast cancer

by Savannah Williamson,Georgia Institute of TechnologyGene enrichment for select Basal-like network modules. Network diagram for eight nonconserved Basal-like modules that include OS genes. Node

Updated on: April 28,2024

Researchers identify novel gene networks associated with aggressive type of breast cancer

by Savannah Williamson,Georgia Institute of TechnologyGene enrichment for select Basal-like network modules. Network diagram for eight nonconserved Basal-like modules that include OS genes. Node

Updated on:April 28,2024

HPV rates for women under 40 increasing, putting them at higher risk of related cancers, study shows

by University of MichiganGardasil vaccine and box. Image: WikipediaHuman papillomavirus infection rates are increasing in women born after 1980 who did not receive the HPV vaccine—putting them at

Updated on: March 01,2024

HPV rates for women under 40 increasing, putting them at higher risk of related cancers, study shows

by University of MichiganGardasil vaccine and box. Image: WikipediaHuman papillomavirus infection rates are increasing in women born after 1980 who did not receive the HPV vaccine—putting them at

Updated on:March 01,2024

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Updated on: August 28,2024

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Updated on:August 28,2024

Workaround erases side effects of promising cell-based cancer therapy

by Bruce Goldman,Stanford University Medical CenterResearch at Stanford are looking at whether a type of immune cell known as a T cell could be taken from a cancer patient, then modified and ret

Updated on: March 01,2024

Workaround erases side effects of promising cell-based cancer therapy

by Bruce Goldman,Stanford University Medical CenterResearch at Stanford are looking at whether a type of immune cell known as a T cell could be taken from a cancer patient, then modified and ret

Updated on:March 01,2024

New spatial tool shows cancer cells rev up synthesis, compared with neighbors

by Talia Ogliore,Washington University in St. LouisMass spectrometry imaging with stable isotope labeling workflow.aMice with orthotopic brain tumors were fed an unlabeled or U−13C g

Updated on: January 12,2024

New spatial tool shows cancer cells rev up synthesis, compared with neighbors

by Talia Ogliore,Washington University in St. LouisMass spectrometry imaging with stable isotope labeling workflow.aMice with orthotopic brain tumors were fed an unlabeled or U−13C g

Updated on:January 12,2024

Genes activated in metastasis also drive the first stages of tumour growth

by Institute for Research in Biomedicine (IRB Barcelona)The overexpression of the gene Serpent in the Drosophila wing causes permanent overgrowth and it is sufficient to promote tumour developmen

Updated on: March 01,2024

Genes activated in metastasis also drive the first stages of tumour growth

by Institute for Research in Biomedicine (IRB Barcelona)The overexpression of the gene Serpent in the Drosophila wing causes permanent overgrowth and it is sufficient to promote tumour developmen

Updated on:March 01,2024

Pathway tied to cancer-driving genome alterations identified

byUTSouthwestern Medical CenterThese images show examples of mitotic chromosome spreads from human cancer cells containing a shattered chromosome (left panel) or extrachromosomal DNA (midd

Updated on: September 27,2024

Pathway tied to cancer-driving genome alterations identified

byUTSouthwestern Medical CenterThese images show examples of mitotic chromosome spreads from human cancer cells containing a shattered chromosome (left panel) or extrachromosomal DNA (midd

Updated on:September 27,2024

New class of cancer mutations discovered in so-called 'junk' DNA

byGarvan Institute of Medical ResearchVisualized DNA damage (green) in human breast cancer cells (blue). Credit: Garvan InstituteUsing artificial intelligence, Garvan Institute researchers have

Updated on: July 05,2024

New class of cancer mutations discovered in so-called 'junk' DNA

byGarvan Institute of Medical ResearchVisualized DNA damage (green) in human breast cancer cells (blue). Credit: Garvan InstituteUsing artificial intelligence, Garvan Institute researchers have

Updated on:July 05,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024