ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on: March 30,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on:March 30,2024

3-D-written model to provide better understanding of cancer spread

by Kayla Wiles,Purdue UniversityThis diagram conceptualizes the 3-D jet writer a Purdue researcher is using to engineer a cancer microenvironment. Credit: Purdue University image/Luis SolorioPur

Updated on: March 14,2024

3-D-written model to provide better understanding of cancer spread

by Kayla Wiles,Purdue UniversityThis diagram conceptualizes the 3-D jet writer a Purdue researcher is using to engineer a cancer microenvironment. Credit: Purdue University image/Luis SolorioPur

Updated on:March 14,2024

Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advant

Updated on: February 18,2024

Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advant

Updated on:February 18,2024

Researcher leads first in-human multiple myeloma study with over 90% response rate

by Indiana University School of MedicineMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Indiana University Melvin and Bren

Updated on: January 30,2024

Researcher leads first in-human multiple myeloma study with over 90% response rate

by Indiana University School of MedicineMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Indiana University Melvin and Bren

Updated on:January 30,2024

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on: September 27,2024

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on:September 27,2024

Dietary supplement helps combat resistance in breast cancer, finds study

byUniversity of BaselCredit: Unsplash/CC0 Public DomainMany cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medicatio

Updated on: January 23,2024

Dietary supplement helps combat resistance in breast cancer, finds study

byUniversity of BaselCredit: Unsplash/CC0 Public DomainMany cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medicatio

Updated on:January 23,2024

Obesity as a risk factor for colorectal cancer underestimated so far, says study

byGerman Cancer Research CenterWeight Change Among Cases and Controls Within 12 Years Before Diagnosis/Interview Lower and upper hinges correspond to 25th and 75th quantile of weight changes, re

Updated on: January 16,2024

Obesity as a risk factor for colorectal cancer underestimated so far, says study

byGerman Cancer Research CenterWeight Change Among Cases and Controls Within 12 Years Before Diagnosis/Interview Lower and upper hinges correspond to 25th and 75th quantile of weight changes, re

Updated on:January 16,2024

Researchers identify protein that may protect the heart during certain cancer treatment regimens

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCirculating Hpx is elevated in mice treated with Dox. (A) Dox-induced chronic cardiomyopathy model in mice. i.p., intraperitoneally. (B

Updated on: February 18,2024

Researchers identify protein that may protect the heart during certain cancer treatment regimens

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCirculating Hpx is elevated in mice treated with Dox. (A) Dox-induced chronic cardiomyopathy model in mice. i.p., intraperitoneally. (B

Updated on:February 18,2024

Many owners see little value in storing their firearms securely, finds study

by Rutgers UniversityCredit: Unsplash/CC0 Public DomainWith more than 400 million privately owned firearms in circulation across the United States, gun violence prevention efforts have emphasized

Updated on: May 21,2024

Many owners see little value in storing their firearms securely, finds study

by Rutgers UniversityCredit: Unsplash/CC0 Public DomainWith more than 400 million privately owned firearms in circulation across the United States, gun violence prevention efforts have emphasized

Updated on:May 21,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Updated on: April 06,2024

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Updated on:April 06,2024

Findings reveal unexpected role of protein OTX2 that drives aggressive medulloblastoma

byBaylor College of MedicineCredit: Unsplash/CC0 Public DomainIn a reportpublishedinNature Cell Biology, researchers at Baylor College of Medicine, Texas Children's Hospita

Updated on: August 03,2024

Findings reveal unexpected role of protein OTX2 that drives aggressive medulloblastoma

byBaylor College of MedicineCredit: Unsplash/CC0 Public DomainIn a reportpublishedinNature Cell Biology, researchers at Baylor College of Medicine, Texas Children's Hospita

Updated on:August 03,2024