Branched-chain amino acids regulate the development and progression of cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeFigure 1. Credit: Agency for Science, Technology and Research (A*STAR), SingaporeResearchers at A*STAR's Singapore Bioimaging

Updated on: April 14,2024

Branched-chain amino acids regulate the development and progression of cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeFigure 1. Credit: Agency for Science, Technology and Research (A*STAR), SingaporeResearchers at A*STAR's Singapore Bioimaging

Updated on:April 14,2024

Prostate cancer: Getting ever closer to diagnosis using an 'electronic nose'

by Politecnico di MilanoPrototype of an electronic nose developed by the Politecnico di Milano in partnership with Humanitas, capable of diagnosing a tumor using a urine sample with 82% accuracy. Cred

Updated on: January 02,2024

Prostate cancer: Getting ever closer to diagnosis using an 'electronic nose'

by Politecnico di MilanoPrototype of an electronic nose developed by the Politecnico di Milano in partnership with Humanitas, capable of diagnosing a tumor using a urine sample with 82% accuracy. Cred

Updated on:January 02,2024

Engineered receptors help the immune system home in on cancer

byUniversity of California, San FranciscoCredit: CC0 Public DomainMost cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they af

Updated on: November 30,2024

Engineered receptors help the immune system home in on cancer

byUniversity of California, San FranciscoCredit: CC0 Public DomainMost cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they af

Updated on:November 30,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024

Early onset colorectal cancer rising fastest in the west

by American Cancer SocietyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Early-onset colorectal cancer -cancer occurring before age 50—is rising most rapidly in

Updated on: April 20,2024

Early onset colorectal cancer rising fastest in the west

by American Cancer SocietyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Early-onset colorectal cancer -cancer occurring before age 50—is rising most rapidly in

Updated on:April 20,2024

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Updated on: April 06,2024

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Updated on:April 06,2024

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on: May 20,2024

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on:May 20,2024

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on: April 18,2024

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on:April 18,2024

Discovery may lead to natural ent-kaurane diterpenoid for NK-based tumor immunotherapy

by Chinese Academy of SciencesCredit: KIBAs early responders in the surveillance of malignant cells, natural killer (NK) cells play a significant role in the control of transformed cells at the t

Updated on: April 14,2024

Discovery may lead to natural ent-kaurane diterpenoid for NK-based tumor immunotherapy

by Chinese Academy of SciencesCredit: KIBAs early responders in the surveillance of malignant cells, natural killer (NK) cells play a significant role in the control of transformed cells at the t

Updated on:April 14,2024

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on: February 18,2024

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on:February 18,2024

Immunotherapy plus an investigational cancer drug improves anti-tumor effects

by Duke University Medical CenterCredit: Pixabay/CC0 Public DomainAn investigational therapy for solid tumors could be especially effective when combined with immunotherapy to target a specific k

Updated on: March 06,2024

Immunotherapy plus an investigational cancer drug improves anti-tumor effects

by Duke University Medical CenterCredit: Pixabay/CC0 Public DomainAn investigational therapy for solid tumors could be especially effective when combined with immunotherapy to target a specific k

Updated on:March 06,2024

New prostate cancer diagnostic pathway paves way for general screening

bySwedish Research CouncilCredit: Pixabay/CC0 Public DomainIn screening for prostate cancer, the risk of overdiagnosis can be halved, a University of Gothenburg study shows. With the proposed di

Updated on: January 12,2024

New prostate cancer diagnostic pathway paves way for general screening

bySwedish Research CouncilCredit: Pixabay/CC0 Public DomainIn screening for prostate cancer, the risk of overdiagnosis can be halved, a University of Gothenburg study shows. With the proposed di

Updated on:January 12,2024