Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice

byThe Spanish National Cancer Research CentreSection of a mouse invasive mesothelioma tumour. Credit: CNIOExposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggr

Updated on: December 22,2023

Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice

byThe Spanish National Cancer Research CentreSection of a mouse invasive mesothelioma tumour. Credit: CNIOExposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggr

Updated on:December 22,2023

How a little-known glycoprotein blocks a cancer cell's immune response

by University of MichiganThe interaction between STC1 and calreticulin. Credit: University of Michigan Rogel Cancer CenterIt was an unexpected discovery that started with an analysis of more than

Updated on: March 26,2024

How a little-known glycoprotein blocks a cancer cell's immune response

by University of MichiganThe interaction between STC1 and calreticulin. Credit: University of Michigan Rogel Cancer CenterIt was an unexpected discovery that started with an analysis of more than

Updated on:March 26,2024

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on: February 20,2024

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on:February 20,2024

Timely surveillance with chest imaging may benefit colorectal cancer patients

byAmerican College of SurgeonsEarly chest imaging may benefit colorectal cancer patients. Credit: American College of SurgeonsColorectal cancer patients with certain clinical characteristics may

Updated on: December 25,2023

Timely surveillance with chest imaging may benefit colorectal cancer patients

byAmerican College of SurgeonsEarly chest imaging may benefit colorectal cancer patients. Credit: American College of SurgeonsColorectal cancer patients with certain clinical characteristics may

Updated on:December 25,2023

Identification of colony stimulating factor 1 receptor offers new strategy for cancer immunotherapy

by Zhang Nannan,Chinese Academy of SciencesIHMT-CSF1R-833 alters the macrophage polarization in M2 macrophages derived from RAW264.7 cells by inducing the M1 macrophage phenotype. Credit: Liang

Updated on: December 25,2023

Identification of colony stimulating factor 1 receptor offers new strategy for cancer immunotherapy

by Zhang Nannan,Chinese Academy of SciencesIHMT-CSF1R-833 alters the macrophage polarization in M2 macrophages derived from RAW264.7 cells by inducing the M1 macrophage phenotype. Credit: Liang

Updated on:December 25,2023

Hope for new therapy to stop advanced skin cancer

bySt. George's University of LondonMorphological effects of P16P1 observed for melanoma cells but not fibroblasts. Representative phase-contrast images of cells after 5 days of growth with o

Updated on: January 10,2024

Hope for new therapy to stop advanced skin cancer

bySt. George's University of LondonMorphological effects of P16P1 observed for melanoma cells but not fibroblasts. Representative phase-contrast images of cells after 5 days of growth with o

Updated on:January 10,2024

Time for a 'Weed-Free January?' How cannabis users could benefit from a 'dry' month

by James MacKillop,The ConversationCredit: RDNE Stock project from PexelsBy now, most are familiar with the idea of Dry January, a voluntary month without alcohol that follows a month when many

Updated on: March 26,2024

Time for a 'Weed-Free January?' How cannabis users could benefit from a 'dry' month

by James MacKillop,The ConversationCredit: RDNE Stock project from PexelsBy now, most are familiar with the idea of Dry January, a voluntary month without alcohol that follows a month when many

Updated on:March 26,2024

Increased risk of prostate cancer in men with BRCA2 gene fault

by Cancer Research UKCredit: CC0 Public DomainMen with the BRCA2 gene fault have an increased risk of prostate cancer and could benefit from PSA (prostate specific antigen) testing to help detect

Updated on: May 09,2024

Increased risk of prostate cancer in men with BRCA2 gene fault

by Cancer Research UKCredit: CC0 Public DomainMen with the BRCA2 gene fault have an increased risk of prostate cancer and could benefit from PSA (prostate specific antigen) testing to help detect

Updated on:May 09,2024

For cancer, a biopharmaceutical company and UC San Diego test another kind of immune cell

by Bradley J. Fikes, The San Diego Union-TribuneWhen the U.S. Food and Drug Administration approved the first cell-based gene therapies for cancer in 2017, advanced malignancies once seen as terminal

Updated on: December 18,2023

For cancer, a biopharmaceutical company and UC San Diego test another kind of immune cell

by Bradley J. Fikes, The San Diego Union-TribuneWhen the U.S. Food and Drug Administration approved the first cell-based gene therapies for cancer in 2017, advanced malignancies once seen as terminal

Updated on:December 18,2023

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on: January 30,2024

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on:January 30,2024

Risks after treatment for cervical neoplasia have declined over time

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainThe treatment of serious prodromal cervical cancer, CIN3, can cause problems during later pregnancy amongst women of fertile age. A new re

Updated on: March 23,2024

Risks after treatment for cervical neoplasia have declined over time

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainThe treatment of serious prodromal cervical cancer, CIN3, can cause problems during later pregnancy amongst women of fertile age. A new re

Updated on:March 23,2024

Preventing 'identity theft' in prostate cancer cells re-sensitizes them to therapy

byUT Southwestern Medical CenterJAK–STAT signaling is required for Enz resistance in TP53/RB1-deficient mCRPC.a, Heat map representing the significantly changed signaling pathways in LNCaP

Updated on: December 22,2023

Preventing 'identity theft' in prostate cancer cells re-sensitizes them to therapy

byUT Southwestern Medical CenterJAK–STAT signaling is required for Enz resistance in TP53/RB1-deficient mCRPC.a, Heat map representing the significantly changed signaling pathways in LNCaP

Updated on:December 22,2023