Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on: February 20,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on:February 20,2024

Collaborative initiative to unravel the role of HLA in individuals with a genetic cancer predisposition

by Peter Saueressig,Heidelberg UniversityGraphical abstract. Credit:International Journal of Cancer(2022). DOI: 10.1002/ijc.34312Scientists from the Heidelberg Institute for Theoreti

Updated on: December 24,2023

Collaborative initiative to unravel the role of HLA in individuals with a genetic cancer predisposition

by Peter Saueressig,Heidelberg UniversityGraphical abstract. Credit:International Journal of Cancer(2022). DOI: 10.1002/ijc.34312Scientists from the Heidelberg Institute for Theoreti

Updated on:December 24,2023

Engineered peptides open new avenue for immunotherapy drug development

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainIn a new study published in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cance

Updated on: May 14,2024

Engineered peptides open new avenue for immunotherapy drug development

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainIn a new study published in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cance

Updated on:May 14,2024

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on: January 07,2024

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on:January 07,2024

Colon cancer screenings are more effective than previously understood: Study

by Peter Dizikes,Massachusetts Institute of TechnologyCredit: Unsplash/CC0 Public DomainScreening for colon cancer reduces cancer rates by substantially more than previous analyses of randomized

Updated on: December 30,2023

Colon cancer screenings are more effective than previously understood: Study

by Peter Dizikes,Massachusetts Institute of TechnologyCredit: Unsplash/CC0 Public DomainScreening for colon cancer reduces cancer rates by substantially more than previous analyses of randomized

Updated on:December 30,2023

Review paper compares two leading pancreatic cancer drugs

by Tyrel Linkhorn,University of ToledoPotential biomarkers in nab-paclitaxel/gemcitabine (a), Folfirinox (b) regimens of drug metabolism and mechanism of action. (c) Macrophages induce gemcitabi

Updated on: May 07,2024

Review paper compares two leading pancreatic cancer drugs

by Tyrel Linkhorn,University of ToledoPotential biomarkers in nab-paclitaxel/gemcitabine (a), Folfirinox (b) regimens of drug metabolism and mechanism of action. (c) Macrophages induce gemcitabi

Updated on:May 07,2024

New open-source software judges accuracy of computer predictions of cancer genetics

byThe Francis Crick InstituteCredit: CC0 Public DomainCancers are often made up of many cells which vary genetically to each other. These genetic differences mean the cancer may be particularly

Updated on: December 22,2023

New open-source software judges accuracy of computer predictions of cancer genetics

byThe Francis Crick InstituteCredit: CC0 Public DomainCancers are often made up of many cells which vary genetically to each other. These genetic differences mean the cancer may be particularly

Updated on:December 22,2023

Discovery could lead to better treatment for leukemia

by University of Illinois at ChicagoBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaPrevious research has revealed that patients with acute my

Updated on: April 14,2024

Discovery could lead to better treatment for leukemia

by University of Illinois at ChicagoBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaPrevious research has revealed that patients with acute my

Updated on:April 14,2024

Genomic data shed light on how lymphoma can turn lethal

byColumbia University Irving Medical CenterCredit: Rebecca Leeman-NeillA study by researchers at Columbia and the Hong Kong University of Science and Technology is helping to clarify how low-gra

Updated on: December 30,2023

Genomic data shed light on how lymphoma can turn lethal

byColumbia University Irving Medical CenterCredit: Rebecca Leeman-NeillA study by researchers at Columbia and the Hong Kong University of Science and Technology is helping to clarify how low-gra

Updated on:December 30,2023

Cancer therapy bexmarilimab awakens immune cells to attack tumors that have avoided detection, research finds

byUniversity of TurkuThe image shows cancer cells and macrophage immune cells. The macrophages are depicted in red whereas the cancer cells are the white-grey spots. The nuclei are shown in blue

Updated on: January 26,2024

Cancer therapy bexmarilimab awakens immune cells to attack tumors that have avoided detection, research finds

byUniversity of TurkuThe image shows cancer cells and macrophage immune cells. The macrophages are depicted in red whereas the cancer cells are the white-grey spots. The nuclei are shown in blue

Updated on:January 26,2024

Mouth cancer cases hit new record in England and Scotland—what you need to know

by Justin Stebbing,The ConversationCredit: Pixabay/CC0 Public DomainCases of mouth cancer have reached a record high in England and Scotland, a newreport shows. Last year, there were more

Updated on: November 30,2024

Mouth cancer cases hit new record in England and Scotland—what you need to know

by Justin Stebbing,The ConversationCredit: Pixabay/CC0 Public DomainCases of mouth cancer have reached a record high in England and Scotland, a newreport shows. Last year, there were more

Updated on:November 30,2024

Identifying new potential in cancer-killing T cells

by Kate Ledger,Mayo ClinicGraphical illustration of a general role of ME1 in resilient CD8+T cells. Credit:Science Advances(2023). DOI: 10.1126/sciadv.adi2414When Joanina Gicob

Updated on: January 25,2024

Identifying new potential in cancer-killing T cells

by Kate Ledger,Mayo ClinicGraphical illustration of a general role of ME1 in resilient CD8+T cells. Credit:Science Advances(2023). DOI: 10.1126/sciadv.adi2414When Joanina Gicob

Updated on:January 25,2024