Immune system holds clues to patients with high-risk smoldering myeloma likely to benefit from treatment

byDana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.10.017For many patients with a condition that often precedes multiple myeloma, e

Updated on: January 02,2024

Immune system holds clues to patients with high-risk smoldering myeloma likely to benefit from treatment

byDana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.10.017For many patients with a condition that often precedes multiple myeloma, e

Updated on:January 02,2024

Doctors call for expanded reporting of medical care given in Immigration and Customs Enforcement detention centers

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA newstudyled by Dr. Annette Dekker, an assistant professor in the Department of Emergency Medicine at UCLA, c

Updated on: May 17,2024

Doctors call for expanded reporting of medical care given in Immigration and Customs Enforcement detention centers

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA newstudyled by Dr. Annette Dekker, an assistant professor in the Department of Emergency Medicine at UCLA, c

Updated on:May 17,2024

Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr

Updated on: March 30,2024

Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr

Updated on:March 30,2024

International team discovers unique pathway for treating deadly children's brain cancer

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: CC0 Public DomainAn international team of researchers led by Yale University, University of Iowa, and the Translational Geno

Updated on: March 12,2024

International team discovers unique pathway for treating deadly children's brain cancer

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: CC0 Public DomainAn international team of researchers led by Yale University, University of Iowa, and the Translational Geno

Updated on:March 12,2024

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on: February 03,2024

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on:February 03,2024

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers

by OncotargetCONSORT diagram. Credit: Ajay SrinivasanRESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can off

Updated on: May 09,2024

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers

by OncotargetCONSORT diagram. Credit: Ajay SrinivasanRESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can off

Updated on:May 09,2024

Study sheds light on mechanisms underlying H. pylori-induced gastric cancer

by Juntendo University Research Promotion CenterThe disruption of Wnt/PCP signaling by the oncoprotein CagA seems to promote gastric carcinogenesis. Credit: Atsushi Takahashi-Kanemitsu, Juntendo Unive

Updated on: February 20,2024

Study sheds light on mechanisms underlying H. pylori-induced gastric cancer

by Juntendo University Research Promotion CenterThe disruption of Wnt/PCP signaling by the oncoprotein CagA seems to promote gastric carcinogenesis. Credit: Atsushi Takahashi-Kanemitsu, Juntendo Unive

Updated on:February 20,2024

Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

by Science China PressThepeptide Pal-DMPOP consists a peptide inhibitor of CD47/SIRPα, a D-peptide inhibitor of PD-1/PD-L1, and a palmitic acid tail conjugated at its N-terminal through a P

Updated on: February 23,2024

Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

by Science China PressThepeptide Pal-DMPOP consists a peptide inhibitor of CD47/SIRPα, a D-peptide inhibitor of PD-1/PD-L1, and a palmitic acid tail conjugated at its N-terminal through a P

Updated on:February 23,2024

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on: May 23,2024

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on:May 23,2024

Researchers develop AI model to improve tumor removal accuracy during breast cancer surgery

by University of North Carolina at Chapel Hill School of Medicine(A) Diagram of model structure. (B) Flowchart of study design. Credit:Annals of Surgical Oncology(2023). DOI: 10.1245/

Updated on: January 30,2024

Researchers develop AI model to improve tumor removal accuracy during breast cancer surgery

by University of North Carolina at Chapel Hill School of Medicine(A) Diagram of model structure. (B) Flowchart of study design. Credit:Annals of Surgical Oncology(2023). DOI: 10.1245/

Updated on:January 30,2024

Non-invasive device more effective for early detection of lymphedema after breast cancer

byCleveland ClinicCredit: Cleveland ClinicSome breast cancer survivors may experience lymphedema, a condition that causes painful swelling of their arm or hand after undergoing surgery or radiat

Updated on: January 10,2024

Non-invasive device more effective for early detection of lymphedema after breast cancer

byCleveland ClinicCredit: Cleveland ClinicSome breast cancer survivors may experience lymphedema, a condition that causes painful swelling of their arm or hand after undergoing surgery or radiat

Updated on:January 10,2024

A new way to predict complications after larynx cancer surgery

by Nicole Fawcett,University of MichiganRebecca Hoesli, M.D., and Matthew Spector, M.D., evaluate an image from the study Credit: University of Michigan Rogel Cancer CenterA technique that illum

Updated on: May 17,2024

A new way to predict complications after larynx cancer surgery

by Nicole Fawcett,University of MichiganRebecca Hoesli, M.D., and Matthew Spector, M.D., evaluate an image from the study Credit: University of Michigan Rogel Cancer CenterA technique that illum

Updated on:May 17,2024