An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on: February 01,2024

An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on:February 01,2024

Stopping cancer from recruiting immune system double agents

by Rush University Medical CenterCredit: Rush University Medical CenterCancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the

Updated on: April 01,2024

Stopping cancer from recruiting immune system double agents

by Rush University Medical CenterCredit: Rush University Medical CenterCancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the

Updated on:April 01,2024

Researchers call for major re-think on sun safety

by Australian National UniversityCredit: CC0 Public DomainMost Australians are familiar with the 'slip, slop, slap' message, but new research suggests we're not taking sun safety seri

Updated on: June 15,2024

Researchers call for major re-think on sun safety

by Australian National UniversityCredit: CC0 Public DomainMost Australians are familiar with the 'slip, slop, slap' message, but new research suggests we're not taking sun safety seri

Updated on:June 15,2024

New study challenges belief that opioids are effective at treating cancer pain

by Annie Slinn,University of WarwickEffect of geographic ancestry on CYP2D6 genotype. CYP2D6 indicates cytochrome P450 2D6. Adapted from information in Table1 of Gaedigk etal., 2017.

Updated on: December 30,2023

New study challenges belief that opioids are effective at treating cancer pain

by Annie Slinn,University of WarwickEffect of geographic ancestry on CYP2D6 genotype. CYP2D6 indicates cytochrome P450 2D6. Adapted from information in Table1 of Gaedigk etal., 2017.

Updated on:December 30,2023

Final overall study analysis continues to show benefit of sacituzumab govitecan in advanced HR+ breast cancer

byDana-Farber Cancer InstituteOverall survival in the intention-to-treat population. This is the planned final analysis of overall survival in the intent-to-treat population of all randomly assi

Updated on: January 22,2024

Final overall study analysis continues to show benefit of sacituzumab govitecan in advanced HR+ breast cancer

byDana-Farber Cancer InstituteOverall survival in the intention-to-treat population. This is the planned final analysis of overall survival in the intent-to-treat population of all randomly assi

Updated on:January 22,2024

Exercise improves cardiorespiratory fitness during and after chemotherapy

by American College of CardiologyCredit: Pixabay/CC0 Public DomainDuring chemotherapy, physical exercise intervention is safe, improves long-term cardiorespiratory fitness, and alleviates some of

Updated on: February 20,2024

Exercise improves cardiorespiratory fitness during and after chemotherapy

by American College of CardiologyCredit: Pixabay/CC0 Public DomainDuring chemotherapy, physical exercise intervention is safe, improves long-term cardiorespiratory fitness, and alleviates some of

Updated on:February 20,2024

Area surrounding a tumor impacts how breast cancer cells grow

by Amanda Gibbs,Oregon Health & Science University“Cancer is acomplex mixture of cancer cells, normal blood cells, tissue and immune cells. Tumor cells themselves alter the microenviro

Updated on: April 07,2024

Area surrounding a tumor impacts how breast cancer cells grow

by Amanda Gibbs,Oregon Health & Science University“Cancer is acomplex mixture of cancer cells, normal blood cells, tissue and immune cells. Tumor cells themselves alter the microenviro

Updated on:April 07,2024

Heart drug could significantly increase survival rates for children with an aggressive form of brain tumour

by University of NottinghamCredit: CC0 Public DomainResearchers at the University of Nottingham have discovered that repurposing a heart drug could significantly increase the survival rate for ch

Updated on: May 17,2024

Heart drug could significantly increase survival rates for children with an aggressive form of brain tumour

by University of NottinghamCredit: CC0 Public DomainResearchers at the University of Nottingham have discovered that repurposing a heart drug could significantly increase the survival rate for ch

Updated on:May 17,2024

Tumors turn gut 'brain cells' into tumor growth promoters

by Tracey Peake,North Carolina State UniversityCredit: CC0 Public DomainResearch led by North Carolina State University has found that when enteric glial cells are exposed to secretions from col

Updated on: March 12,2024

Tumors turn gut 'brain cells' into tumor growth promoters

by Tracey Peake,North Carolina State UniversityCredit: CC0 Public DomainResearch led by North Carolina State University has found that when enteric glial cells are exposed to secretions from col

Updated on:March 12,2024

Study identifies new mechanisms that boost p53 signaling and tumor suppression

by Ludwig Cancer ResearchGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.04.010A team led by Ludwig Stanford's Laura Attardi explored novel mechanisms

Updated on: February 01,2024

Study identifies new mechanisms that boost p53 signaling and tumor suppression

by Ludwig Cancer ResearchGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.04.010A team led by Ludwig Stanford's Laura Attardi explored novel mechanisms

Updated on:February 01,2024

Neutralizing the side effects of epidermal growth factor inhibitor drugs

by Justin Jackson , Medical XpressIdentifying compounds that block anti-EGFR monoclonal antibodies binding to EGFR. (A) Illustration of the process used to identify lead compounds. "Hit" mol

Updated on: February 03,2024

Neutralizing the side effects of epidermal growth factor inhibitor drugs

by Justin Jackson , Medical XpressIdentifying compounds that block anti-EGFR monoclonal antibodies binding to EGFR. (A) Illustration of the process used to identify lead compounds. "Hit" mol

Updated on:February 03,2024

Immunotherapy with two novel drugs shows activity in colorectal cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainA combination of two next-generation immunotherapy drugs has shown promising clinical activity in treating patients with refractor

Updated on: December 28,2023

Immunotherapy with two novel drugs shows activity in colorectal cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainA combination of two next-generation immunotherapy drugs has shown promising clinical activity in treating patients with refractor

Updated on:December 28,2023