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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res
One in five GPs unwilling to prescribe aspirin to people at risk of bowel cancer, finds UK study

One in five GPs unwilling to prescribe aspirin to people at risk of bowel cancer, finds UK study

by University of LeedsCredit: Unsplash/CC0 Public DomainOne in five GPs could be unwilling to prescribe aspirin to patients with a cancer-causing syndrome, despite national guidelines advising it

One in five GPs unwilling to prescribe aspirin to people at risk of bowel cancer, finds UK study

by University of LeedsCredit: Unsplash/CC0 Public DomainOne in five GPs could be unwilling to prescribe aspirin to patients with a cancer-causing syndrome, despite national guidelines advising it
Does living along the US-Mexico border affect the chances of survival among children with leukemia?

Does living along the US-Mexico border affect the chances of survival among children with leukemia?

byWileyCredit: Unsplash/CC0 Public DomainResiding in border regions was linked with a higher risk of dying within five years among children with acute lymphoblastic leukemia, the most common typ

Does living along the US-Mexico border affect the chances of survival among children with leukemia?

byWileyCredit: Unsplash/CC0 Public DomainResiding in border regions was linked with a higher risk of dying within five years among children with acute lymphoblastic leukemia, the most common typ
Genetic variation explains racial disparity in esophageal cancer cases

Genetic variation explains racial disparity in esophageal cancer cases

by University of California - San DiegoCredit: Pradipta Ghosh et al,JCI Insight(2022). DOI: 10.1172/jci.insight.161334Esophageal adenocarcinoma (EAC) is a type of cancer affecting the

Genetic variation explains racial disparity in esophageal cancer cases

by University of California - San DiegoCredit: Pradipta Ghosh et al,JCI Insight(2022). DOI: 10.1172/jci.insight.161334Esophageal adenocarcinoma (EAC) is a type of cancer affecting the
Unique gene activity discovered in people with both stroke and cancer

Unique gene activity discovered in people with both stroke and cancer

Not all strokes have a clear-cut cause like high blood pressure or smoking. For those so-called cryptogenic strokes, new research suggests cancer might be the trigger—a finding that could potentially

Unique gene activity discovered in people with both stroke and cancer

Not all strokes have a clear-cut cause like high blood pressure or smoking. For those so-called cryptogenic strokes, new research suggests cancer might be the trigger—a finding that could potentially
IKZF1 Alterations an Independent Marker of AML Risk

IKZF1 Alterations an Independent Marker of AML Risk

February 2024Leah LawrenceMutatedIKZF1was an independent marker of adverse risk in patients with acute myeloid leukemia (AML), and patients whose AML had these alterations were at higher r

IKZF1 Alterations an Independent Marker of AML Risk

February 2024Leah LawrenceMutatedIKZF1was an independent marker of adverse risk in patients with acute myeloid leukemia (AML), and patients whose AML had these alterations were at higher r
Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

by University of Chicago Medical Center5-AZA-sensitive and 5-AZA-resistant leukemia cells have distinctly different chromatin structures. Credit: Jason ChengDrug resistance is a major obstacle to

Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

by University of Chicago Medical Center5-AZA-sensitive and 5-AZA-resistant leukemia cells have distinctly different chromatin structures. Credit: Jason ChengDrug resistance is a major obstacle to
Novel biomarker found in ovarian cancer patients can predict response to therapy

Novel biomarker found in ovarian cancer patients can predict response to therapy

by University of Chicago Medical CenterTumor-specific expression of CT45 stimulates the patient's immune system to fight the cancer and improves the efficacy of platinum-based chemotherapy. C

Novel biomarker found in ovarian cancer patients can predict response to therapy

by University of Chicago Medical CenterTumor-specific expression of CT45 stimulates the patient's immune system to fight the cancer and improves the efficacy of platinum-based chemotherapy. C
Diabetes drug reduces drug resistance in lung cancer, improving chemotherapy effectiveness

Diabetes drug reduces drug resistance in lung cancer, improving chemotherapy effectiveness

byUniversity of MissouriCredit: Pixabay/CC0 Public DomainA medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according t

Diabetes drug reduces drug resistance in lung cancer, improving chemotherapy effectiveness

byUniversity of MissouriCredit: Pixabay/CC0 Public DomainA medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according t
Drug combo slows progression in advanced breast cancer

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth
Researchers demonstrate RAS dimers are essential for cancer

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of
Novel silver compounds offer a potential cancer treatment breakthrough

Novel silver compounds offer a potential cancer treatment breakthrough

by Marianne J. Cronjé And Reinout Meijboom,The ConversationOesophageal cancer cells before the silver-based compounds have been added.The development of chemotherapeutic drugs to treat various c

Novel silver compounds offer a potential cancer treatment breakthrough

by Marianne J. Cronjé And Reinout Meijboom,The ConversationOesophageal cancer cells before the silver-based compounds have been added.The development of chemotherapeutic drugs to treat various c