HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on: December 21,2023 7

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on:December 21,2023 7

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on: December 20,2023 10

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on:December 20,2023 10

Why some cancers affect only young women

byUniversity of GenevaCredit: CC0 Public DomainAmong several forms of pancreatic cancer, one of them specifically affects women, often young. How is this possible, even though the pancreas is an

Updated on: December 18,2023 18

Why some cancers affect only young women

byUniversity of GenevaCredit: CC0 Public DomainAmong several forms of pancreatic cancer, one of them specifically affects women, often young. How is this possible, even though the pancreas is an

Updated on:December 18,2023 18

New study reveals how blood cancer cells escape the immune system's natural killer cells

byUniversity of HelsinkiGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.11.008The advent of T-cell therapies, where cells of the immune system are directed towa

Updated on: January 26,2024 18

New study reveals how blood cancer cells escape the immune system's natural killer cells

byUniversity of HelsinkiGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.11.008The advent of T-cell therapies, where cells of the immune system are directed towa

Updated on:January 26,2024 18

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on: December 21,2023 10

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on:December 21,2023 10

Are inflammatory bowel disease patients more at risk of colorectal cancer

In a recent study published in the journalFrontiers in Medicine, researchers analyzed data from a large cohort of inflammatory bowel disease (IBD) patients and compared the risk and frequency of

Updated on: October 30,2023 16

Are inflammatory bowel disease patients more at risk of colorectal cancer

In a recent study published in the journalFrontiers in Medicine, researchers analyzed data from a large cohort of inflammatory bowel disease (IBD) patients and compared the risk and frequency of

Updated on:October 30,2023 16

Immunotherapy Combo Boosts Survival in Metastatic Melanoma

byColleen Fleisson August 19, 2023For patients diagnosed with advancedmetastatic melanomathat does not respond to the commonly utilized PD-1 inhibitors, immunotherapy drugs ipi

Updated on: December 19,2023 16

Immunotherapy Combo Boosts Survival in Metastatic Melanoma

byColleen Fleisson August 19, 2023For patients diagnosed with advancedmetastatic melanomathat does not respond to the commonly utilized PD-1 inhibitors, immunotherapy drugs ipi

Updated on:December 19,2023 16

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on: December 18,2023 22

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on:December 18,2023 22

Immunotherapy may become new first line treatment in some metastatic colorectal cancers

byEuropean Society for Medical OncologyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Immunotherapy with nivolumab and low-dose ipilimumab could become a new fi

Updated on: December 18,2023 19

Immunotherapy may become new first line treatment in some metastatic colorectal cancers

byEuropean Society for Medical OncologyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Immunotherapy with nivolumab and low-dose ipilimumab could become a new fi

Updated on:December 18,2023 19

Targeted therapy drug helps women with aggressive breast cancer live longer

by Denise Heady,University of California, Los AngelesSenior author Dr. Dennis Slamon says “there is absolutely no reason to wait” to give women treatment that combines ribociclib with hormone th

Updated on: December 22,2023 10

Targeted therapy drug helps women with aggressive breast cancer live longer

by Denise Heady,University of California, Los AngelesSenior author Dr. Dennis Slamon says “there is absolutely no reason to wait” to give women treatment that combines ribociclib with hormone th

Updated on:December 22,2023 10

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Updated on: December 25,2023 11

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Updated on:December 25,2023 11

Anti-anxiety drug may improve brain cancer survival chances

Anti-anxiety drug may improve brain cancer survival chancesbyFlinders UniversityGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0A new study shows that cerebrospinal fluid reduces c

Updated on: October 30,2023 8

Anti-anxiety drug may improve brain cancer survival chances

Anti-anxiety drug may improve brain cancer survival chancesbyFlinders UniversityGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0A new study shows that cerebrospinal fluid reduces c

Updated on:October 30,2023 8