Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on: April 18,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on:April 18,2024

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne

Updated on: September 07,2024

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne

Updated on:September 07,2024

US requires new info on breast density with all mammograms

by Matthew PerroneA radiologist uses a magnifying glass to check mammograms for breast cancer in Los Angeles, May 6, 2010. U.S. women getting mammograms will soon receive information about their breas

Updated on: January 02,2024

US requires new info on breast density with all mammograms

by Matthew PerroneA radiologist uses a magnifying glass to check mammograms for breast cancer in Los Angeles, May 6, 2010. U.S. women getting mammograms will soon receive information about their breas

Updated on:January 02,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on: June 06,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on:June 06,2024

Researchers uncover how breast cancer cells become resistant to therapy

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainAbout one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them res

Updated on: February 24,2024

Researchers uncover how breast cancer cells become resistant to therapy

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainAbout one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them res

Updated on:February 24,2024

Too often, women aren't told of sexual side effects of cancer treatments

by Cara MurezWhen a man has cancer in an area that affects sexual function, his doctor is likely to discuss it with him.But the same is not true for a woman who has cancer in a sex organ, according to

Updated on: January 02,2024

Too often, women aren't told of sexual side effects of cancer treatments

by Cara MurezWhen a man has cancer in an area that affects sexual function, his doctor is likely to discuss it with him.But the same is not true for a woman who has cancer in a sex organ, according to

Updated on:January 02,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on: March 30,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on:March 30,2024

Research team reveals mechanisms at work in progression of pancreatic cysts to pancreatic cancer

by University of California, San FranciscoPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cysts have gained substantial

Updated on: January 30,2024

Research team reveals mechanisms at work in progression of pancreatic cysts to pancreatic cancer

by University of California, San FranciscoPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cysts have gained substantial

Updated on:January 30,2024

Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on: February 03,2024

Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on:February 03,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on: February 03,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on:February 03,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on: June 15,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on:June 15,2024

Unlocking the body's hidden weapon against cancer: The role of broken chromosomes

by Zhejiang UniversityCredit: Pixabay/CC0 Public DomainScientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (c

Updated on: April 28,2024

Unlocking the body's hidden weapon against cancer: The role of broken chromosomes

by Zhejiang UniversityCredit: Pixabay/CC0 Public DomainScientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (c

Updated on:April 28,2024