The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on: April 28,2024 0

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on:April 28,2024 0

Ultrasound activated microbubbles enhance the activity of standard of care therapeutics in pancreatic cancer

byTranslational Genomics Research InstituteUltrasound administration setup and drug dosing timeline. A. Photograph of the ultrasound administration setup; B. Schematic depiction of the ultrasoun

Updated on: December 19,2023 10

Ultrasound activated microbubbles enhance the activity of standard of care therapeutics in pancreatic cancer

byTranslational Genomics Research InstituteUltrasound administration setup and drug dosing timeline. A. Photograph of the ultrasound administration setup; B. Schematic depiction of the ultrasoun

Updated on:December 19,2023 10

Researchers design new hydrogel for more targeted cancer treatments

by Safa Jinje,University of TorontoGraphical abstract. Credit:Materials Today(2022). DOI: 10.1016/j.mattod.2022.01.023University of Toronto researchers have designed a new way to gro

Updated on: December 22,2023 22

Researchers design new hydrogel for more targeted cancer treatments

by Safa Jinje,University of TorontoGraphical abstract. Credit:Materials Today(2022). DOI: 10.1016/j.mattod.2022.01.023University of Toronto researchers have designed a new way to gro

Updated on:December 22,2023 22

New model identifies drugs that shouldn't be taken together

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainAny drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line t

Updated on: March 21,2024 13

New model identifies drugs that shouldn't be taken together

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainAny drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line t

Updated on:March 21,2024 13

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on: December 27,2023 10

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on:December 27,2023 10

Scientists learn what women know—and don't know—about breast density and cancer risk

byDartmouth-Hitchcock Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast density is an important risk factor for breast cancer

Updated on: December 22,2023 23

Scientists learn what women know—and don't know—about breast density and cancer risk

byDartmouth-Hitchcock Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainBreast density is an important risk factor for breast cancer

Updated on:December 22,2023 23

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023 10

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023 10

Five facts you may not know about brain tumors

by Laura Hegwer,Rush University Medical CenterCredit: Unsplash/CC0 Public DomainBrain tumors scare most people, but there are still reasons to be hopeful if you learn you have an abnormal growth

Updated on: December 23,2023 10

Five facts you may not know about brain tumors

by Laura Hegwer,Rush University Medical CenterCredit: Unsplash/CC0 Public DomainBrain tumors scare most people, but there are still reasons to be hopeful if you learn you have an abnormal growth

Updated on:December 23,2023 10

Antioxidant use during chemotherapy risky for breast cancer patients

by SWOGCredit: CC0 Public DomainBreast cancer patients who take the dietary supplements known as antioxidants, as well as iron, vitamin B12, and omega-3 fatty acids, during chemotherapy may be at incr

Updated on: December 23,2023 24

Antioxidant use during chemotherapy risky for breast cancer patients

by SWOGCredit: CC0 Public DomainBreast cancer patients who take the dietary supplements known as antioxidants, as well as iron, vitamin B12, and omega-3 fatty acids, during chemotherapy may be at incr

Updated on:December 23,2023 24

Cancer therapy may be aided by induced macropinocytosis, a rare form of cell death

by Jeff Hansen,University of Alabama at BirminghamMohammad Athar. Credit: UABIn laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast

Updated on: December 22,2023 21

Cancer therapy may be aided by induced macropinocytosis, a rare form of cell death

by Jeff Hansen,University of Alabama at BirminghamMohammad Athar. Credit: UABIn laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast

Updated on:December 22,2023 21

Three-drug combination therapy effective in patients with high-risk chronic lymphocytic leukemia, trial shows

byDana-Farber Cancer InstituteNew research shows that genetics account for only five to 10 per cent of risk for most human diseases, and that gene testing is a poor predictor of whether someone

Updated on: January 04,2024 9

Three-drug combination therapy effective in patients with high-risk chronic lymphocytic leukemia, trial shows

byDana-Farber Cancer InstituteNew research shows that genetics account for only five to 10 per cent of risk for most human diseases, and that gene testing is a poor predictor of whether someone

Updated on:January 04,2024 9

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on: December 21,2023 10

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on:December 21,2023 10