Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on: December 18,2023

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on:December 18,2023

Flipping the switch: Scientists shed new light on genetic changes that turn 'on' cancer genes

bySalk InstituteWhen genetic mutations cause chromosomes to break apart and fuse together in different ways, normal cells can become cancerous. In this image, normal chromosomes (blue) are shown

Updated on: December 20,2023

Flipping the switch: Scientists shed new light on genetic changes that turn 'on' cancer genes

bySalk InstituteWhen genetic mutations cause chromosomes to break apart and fuse together in different ways, normal cells can become cancerous. In this image, normal chromosomes (blue) are shown

Updated on:December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on: December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on:December 20,2023

New AI tool predicts risk for chronic pain in cancer patients

by Eric Hamilton,University of FloridaOverview of our transformer-based chronic pain prediction model: Three different data inputs are passed into dedicated encoders to generate a final vector t

Updated on: August 27,2024

New AI tool predicts risk for chronic pain in cancer patients

by Eric Hamilton,University of FloridaOverview of our transformer-based chronic pain prediction model: Three different data inputs are passed into dedicated encoders to generate a final vector t

Updated on:August 27,2024

'Ray of hope': New advances in fighting a range of cancers

Credit: Pixabay/CC0 Public DomainNew advances in the fight against a range of cancers have been revealed at the annual meeting of the American Society of Clinical Oncology (ASCO), which wraps up in Ch

Updated on: January 10,2024

'Ray of hope': New advances in fighting a range of cancers

Credit: Pixabay/CC0 Public DomainNew advances in the fight against a range of cancers have been revealed at the annual meeting of the American Society of Clinical Oncology (ASCO), which wraps up in Ch

Updated on:January 10,2024

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023

How cancer cells move and metastasize is influenced by the fluids surrounding them

by Yizeng Li,The ConversationCredit: CC0 Public DomainCell migration, or how cells move in the body, is essential to both normal body function and disease progression. Cell movement is what allo

Updated on: December 18,2023

How cancer cells move and metastasize is influenced by the fluids surrounding them

by Yizeng Li,The ConversationCredit: CC0 Public DomainCell migration, or how cells move in the body, is essential to both normal body function and disease progression. Cell movement is what allo

Updated on:December 18,2023

Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer

byeLifeA cell-by-cell tapestry of prostate cancer progression, which the authors created by applying a technique called UMAP to the entire dataset from their study. Credit: Germanos et al. (CC B

Updated on: December 27,2023

Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer

byeLifeA cell-by-cell tapestry of prostate cancer progression, which the authors created by applying a technique called UMAP to the entire dataset from their study. Credit: Germanos et al. (CC B

Updated on:December 27,2023

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on: December 22,2023

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on:December 22,2023

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on: December 26,2023

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on:December 26,2023

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on: December 26,2023

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on:December 26,2023

Measuring changes in brain tissue oxygenation for personalized cancer radiotherapy

bySPIEResearchers used a functional near-infrared spectroscopy (fNIRS) device attached to the patient's forehead to measure changes in hemoglobin and tissue oxygenation levels. The device wa

Updated on: December 19,2023

Measuring changes in brain tissue oxygenation for personalized cancer radiotherapy

bySPIEResearchers used a functional near-infrared spectroscopy (fNIRS) device attached to the patient's forehead to measure changes in hemoglobin and tissue oxygenation levels. The device wa

Updated on:December 19,2023