CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on: December 22,2023 12

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on:December 22,2023 12

Variants in BRCA1/2 and MMR genes in children with cancer

by Stefan Zorn, Medizinische Hochschule HannoverProfessor Dr. Christian Kratz, initiator of the international study that investigated the cancer risk of disease-relevant variants in BRCA1/2 and MMR ge

Updated on: December 18,2023 12

Variants in BRCA1/2 and MMR genes in children with cancer

by Stefan Zorn, Medizinische Hochschule HannoverProfessor Dr. Christian Kratz, initiator of the international study that investigated the cancer risk of disease-relevant variants in BRCA1/2 and MMR ge

Updated on:December 18,2023 12

Flipping the switch: Scientists shed new light on genetic changes that turn 'on' cancer genes

bySalk InstituteWhen genetic mutations cause chromosomes to break apart and fuse together in different ways, normal cells can become cancerous. In this image, normal chromosomes (blue) are shown

Updated on: December 20,2023 8

Flipping the switch: Scientists shed new light on genetic changes that turn 'on' cancer genes

bySalk InstituteWhen genetic mutations cause chromosomes to break apart and fuse together in different ways, normal cells can become cancerous. In this image, normal chromosomes (blue) are shown

Updated on:December 20,2023 8

Health Disparities Persist in Hemophilia Life Expectancy

January 2024Lara C. Pullen, PhDBetween 1999 and 2020, recorded hemophilia death (rHD) rates in the U.S. improved in males across all racial and ethnic groups.Stacey A. Fedewa, PhD, MPH,of

Updated on: February 18,2024 11

Health Disparities Persist in Hemophilia Life Expectancy

January 2024Lara C. Pullen, PhDBetween 1999 and 2020, recorded hemophilia death (rHD) rates in the U.S. improved in males across all racial and ethnic groups.Stacey A. Fedewa, PhD, MPH,of

Updated on:February 18,2024 11

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on: February 20,2024 14

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on:February 20,2024 14

ASCO endorses integrative oncology guidelines for breast cancer patients

by Diane Mapes,Fred Hutchinson Cancer Research CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainThe first time Elizabeth Johnson told her on

Updated on: March 09,2024 20

ASCO endorses integrative oncology guidelines for breast cancer patients

by Diane Mapes,Fred Hutchinson Cancer Research CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainThe first time Elizabeth Johnson told her on

Updated on:March 09,2024 20

New imaging system and artificial intelligence algorithm accurately identify brain tumors

byNYU Langone HealthStimulated Raman histologic images of diffuse astrocytoma (left) and meningioma (right). Credit: Daniel Orringer, NYU Langone HealthA novel method of combining advanced optic

Updated on: December 22,2023 11

New imaging system and artificial intelligence algorithm accurately identify brain tumors

byNYU Langone HealthStimulated Raman histologic images of diffuse astrocytoma (left) and meningioma (right). Credit: Daniel Orringer, NYU Langone HealthA novel method of combining advanced optic

Updated on:December 22,2023 11

Local radiotherapy improves survival in metastatic prostate cancer with low disease burden

byEuropean Society for Medical OncologyRadiotherapy to the prostate improves overall survival in men newly diagnosed with metastatic prostate cancer who have a low metastatic disease burden but

Updated on: December 18,2023 13

Local radiotherapy improves survival in metastatic prostate cancer with low disease burden

byEuropean Society for Medical OncologyRadiotherapy to the prostate improves overall survival in men newly diagnosed with metastatic prostate cancer who have a low metastatic disease burden but

Updated on:December 18,2023 13

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024 4

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024 4

New mechanism of radioresistance formation shown in lung adenocarcinoma

by Zhang Nannan,Chinese Academy of SciencesGOLPH3 mediates radioresistance formation of lung adenocarcinoma. Credit: Kong PeizhongA research team led by Prof. Han Wei from the Hefei Institutes o

Updated on: December 22,2023 6

New mechanism of radioresistance formation shown in lung adenocarcinoma

by Zhang Nannan,Chinese Academy of SciencesGOLPH3 mediates radioresistance formation of lung adenocarcinoma. Credit: Kong PeizhongA research team led by Prof. Han Wei from the Hefei Institutes o

Updated on:December 22,2023 6

Novel genetic signature that can predict some kinds of breast cancer is identified

by Maria Fernanda Ziegler,FAPESPBlood vessels from the retina of a mouse with retinopathy, normal and pathological vessels stained green and red respectively. Credit: Ricardo GiordanoResearchers

Updated on: December 22,2023 12

Novel genetic signature that can predict some kinds of breast cancer is identified

by Maria Fernanda Ziegler,FAPESPBlood vessels from the retina of a mouse with retinopathy, normal and pathological vessels stained green and red respectively. Credit: Ricardo GiordanoResearchers

Updated on:December 22,2023 12

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on: December 27,2023 12

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on:December 27,2023 12