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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Drug development in stem cell-derived liver organoid models

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli
More Evidence Gene Therapy Might Cure Sickle Cell Disease

More Evidence Gene Therapy Might Cure Sickle Cell Disease

By Cara MurezHealthDay ReporterMONDAY, June 12, 2023 (HealthDay News) -- A clinical trial that’s attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and succe

More Evidence Gene Therapy Might Cure Sickle Cell Disease

By Cara MurezHealthDay ReporterMONDAY, June 12, 2023 (HealthDay News) -- A clinical trial that’s attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and succe
Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child
Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas
Why don't T cells destroy solid tumors during immunotherapy?

Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe

Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe
NXC-201 Demonstrates Feasibility of BCMA-Directed CAR T-Cell Therapy in Relapsed/Refractory AL

NXC-201 Demonstrates Feasibility of BCMA-Directed CAR T-Cell Therapy in Relapsed/Refractory AL

September 30, 2023Ryan Scotthe novel anti-BCMA CAR T-cell therapy NXC-201 displayed safety and elicited hematologic and organ responses in patients with relapsed/refractory amyloid light chain amyloid

NXC-201 Demonstrates Feasibility of BCMA-Directed CAR T-Cell Therapy in Relapsed/Refractory AL

September 30, 2023Ryan Scotthe novel anti-BCMA CAR T-cell therapy NXC-201 displayed safety and elicited hematologic and organ responses in patients with relapsed/refractory amyloid light chain amyloid
Can Artificial Intelligence–Driven Chatbots Correctly Answer Questions about Cancer?

Can Artificial Intelligence–Driven Chatbots Correctly Answer Questions about Cancer?

by Edward WinsteadArtificial intelligence (AI) technologies have become part of everyday life for many people, helping with mundane tasks such as shopping online and using social media. But can AI-dri

Can Artificial Intelligence–Driven Chatbots Correctly Answer Questions about Cancer?

by Edward WinsteadArtificial intelligence (AI) technologies have become part of everyday life for many people, helping with mundane tasks such as shopping online and using social media. But can AI-dri
Researchers surprised by high levels of alcohol consumption among cancer survivors

Researchers surprised by high levels of alcohol consumption among cancer survivors

by National Comprehensive Cancer NetworkCredit: CC0 Public DomainNew research in the January 2020 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkuses data from the Natio

Researchers surprised by high levels of alcohol consumption among cancer survivors

by National Comprehensive Cancer NetworkCredit: CC0 Public DomainNew research in the January 2020 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkuses data from the Natio
To stop spread of cancer, researchers target two signaling switches that trigger new blood vessel growth

To stop spread of cancer, researchers target two signaling switches that trigger new blood vessel growth

byUniversity of East AngliaCredit: Unsplash/CC0 Public DomainHitting two targets at the same time may be the key to stopping the spread of aggressive cancers, according to new research from the

To stop spread of cancer, researchers target two signaling switches that trigger new blood vessel growth

byUniversity of East AngliaCredit: Unsplash/CC0 Public DomainHitting two targets at the same time may be the key to stopping the spread of aggressive cancers, according to new research from the
Helping blood cells regenerate after radiation therapy

Helping blood cells regenerate after radiation therapy

Method boosts differentiation of stem cells into mature blood cell types, may help leukemia and lymphoma patients.Anne Trafton|MIT News OfficePublication Date:October 24, 2018 PRESS INQUIR

Helping blood cells regenerate after radiation therapy

Method boosts differentiation of stem cells into mature blood cell types, may help leukemia and lymphoma patients.Anne Trafton|MIT News OfficePublication Date:October 24, 2018 PRESS INQUIR
Exploring the links between diet and cancer

Exploring the links between diet and cancer

Omer Yilmaz’s work on how diet influences intestinal stem cells could lead to new ways to treat or prevent gastrointestinal cancers.Anne Trafton|MIT News OfficePublication Date:May 25, 202

Exploring the links between diet and cancer

Omer Yilmaz’s work on how diet influences intestinal stem cells could lead to new ways to treat or prevent gastrointestinal cancers.Anne Trafton|MIT News OfficePublication Date:May 25, 202
ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28