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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Structural insights reveal how SPOP protein contributes to cancer

Structural insights reveal how SPOP protein contributes to cancer

bySt. Jude Children's Research HospitalL to R: L to R: Brian O’Flynn, Ph.D., Matthew Cuneo, Ph.D., and Tanja Mittag, Ph.D. Credit: St. Jude Children's Research HospitalSPOP is the most m

Structural insights reveal how SPOP protein contributes to cancer

bySt. Jude Children's Research HospitalL to R: L to R: Brian O’Flynn, Ph.D., Matthew Cuneo, Ph.D., and Tanja Mittag, Ph.D. Credit: St. Jude Children's Research HospitalSPOP is the most m
A blood sample 24 hours after the start of chemotherapy can predict survival

A blood sample 24 hours after the start of chemotherapy can predict survival

byUniversity of BergenMass cytometry analysis of early response evaluation by single-cell signaling to profile.aPeripheral blood samples were collected from 32 AML patients treated w

A blood sample 24 hours after the start of chemotherapy can predict survival

byUniversity of BergenMass cytometry analysis of early response evaluation by single-cell signaling to profile.aPeripheral blood samples were collected from 32 AML patients treated w
Unveiling the non-canonical functions of EZH2 in prostate cancer

Unveiling the non-canonical functions of EZH2 in prostate cancer

by Impact Journals LLCProstate cancer cells. Credit: NIH Image GalleryA new editorial paper was published inOncotargettitled "Unveiling the non-canonical functions of EZH2 in prostate

Unveiling the non-canonical functions of EZH2 in prostate cancer

by Impact Journals LLCProstate cancer cells. Credit: NIH Image GalleryA new editorial paper was published inOncotargettitled "Unveiling the non-canonical functions of EZH2 in prostate
Method that uses combination of immune cells could provide clearer prognoses

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-
A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024
Genes reveal kidney cancer's risk of recurrence

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:
Metabolic adaptation ensures survival of colon cancer cells

Metabolic adaptation ensures survival of colon cancer cells

byGerman Cancer Research CenterCredit: CC0 Public DomainColon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to

Metabolic adaptation ensures survival of colon cancer cells

byGerman Cancer Research CenterCredit: CC0 Public DomainColon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to
Novel form of immunotherapy could revolutionize cancer treatment

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor
How genetic therapies transformed the lives of sickle cell patients

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha