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Breakthroughs
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A brief history of drug-fueled combatants

A brief history of drug-fueled combatants

by Colin Davidson,The ConversationA chess piece depicting a berserker biting his shield. Credit:National Museums Scotland/Wikimedia Commons,CC BY-SAMy friend Luke used to drink a pin

A brief history of drug-fueled combatants

by Colin Davidson,The ConversationA chess piece depicting a berserker biting his shield. Credit:National Museums Scotland/Wikimedia Commons,CC BY-SAMy friend Luke used to drink a pin
Uncovering the Heart-Brain-Immune Connection: How Sleep Promotes Healing After a Heart Attack

Uncovering the Heart-Brain-Immune Connection: How Sleep Promotes Healing After a Heart Attack

Recent discoveries in cardiovascular and neurological research have uncovered a fascinating new link between the heart, brain, and immune system.

Uncovering the Heart-Brain-Immune Connection: How Sleep Promotes Healing After a Heart Attack

Recent discoveries in cardiovascular and neurological research have uncovered a fascinating new link between the heart, brain, and immune system.
Autophagy-tethering compounds may open new directions in targeted drug discovery

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting
Scientists discover a framework in the brain for organizing the order of things

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix
New drug helps narrow racial survival disparity in patients with acute myeloid leukemia: Study

New drug helps narrow racial survival disparity in patients with acute myeloid leukemia: Study

by Perelman School of Medicine at the University of PennsylvaniaBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaNon-Hispanic Black patients wi

New drug helps narrow racial survival disparity in patients with acute myeloid leukemia: Study

by Perelman School of Medicine at the University of PennsylvaniaBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaNon-Hispanic Black patients wi
New insight into the protein mutations that cause Rett syndrome

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4
Researchers discover a mechanism that could improve platinum-based cancer therapy

Researchers discover a mechanism that could improve platinum-based cancer therapy

by CU Anschutz Medical CampusCredit: CC0 Public DomainResearchers have identified a protein that, when targeted, enables cisplatin-resistant cancer cells to become responsive to treatment. Cispla

Researchers discover a mechanism that could improve platinum-based cancer therapy

by CU Anschutz Medical CampusCredit: CC0 Public DomainResearchers have identified a protein that, when targeted, enables cisplatin-resistant cancer cells to become responsive to treatment. Cispla
New treatment options for advanced myelofibrosis and other blood malignancies show promise

New treatment options for advanced myelofibrosis and other blood malignancies show promise

byUniversity of Miami Leonard M. Miller School of MedicineCredit: CC0 Public DomainFew standard treatments have been available for advanced myelofibrosis, a bone marrow disorder characterized by

New treatment options for advanced myelofibrosis and other blood malignancies show promise

byUniversity of Miami Leonard M. Miller School of MedicineCredit: CC0 Public DomainFew standard treatments have been available for advanced myelofibrosis, a bone marrow disorder characterized by
Health care database analysis highlights lingering symptoms long after COVID-19 infection

Health care database analysis highlights lingering symptoms long after COVID-19 infection

byUniversity of OxfordIncidence rate of post-acute COVID-19 symptoms in the infected cohort. Note: Plots have been scaled independently so that all incidences can be visualized. Credit:eCl

Health care database analysis highlights lingering symptoms long after COVID-19 infection

byUniversity of OxfordIncidence rate of post-acute COVID-19 symptoms in the infected cohort. Note: Plots have been scaled independently so that all incidences can be visualized. Credit:eCl
Plozasiran reduces triglyceride levels by 74% at 24 weeks

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red