A breakthrough with a new cancer vaccine

by Translational Research InstituteCredit: Translational Research InstituteScientists are ready to trial a new cancer vaccine in humans following the successful outcome of their preclinical studies.Th

Updated on: March 26,2024

A breakthrough with a new cancer vaccine

by Translational Research InstituteCredit: Translational Research InstituteScientists are ready to trial a new cancer vaccine in humans following the successful outcome of their preclinical studies.Th

Updated on:March 26,2024

Atopic dermatitis in children tied to learning, memory difficulties

by Lori SolomonPediatric atopic dermatitis (AD) is associated with greater odds of reported difficulties in learning and memory, but this association is driven by children with neurodevelopmental como

Updated on: March 20,2024

Atopic dermatitis in children tied to learning, memory difficulties

by Lori SolomonPediatric atopic dermatitis (AD) is associated with greater odds of reported difficulties in learning and memory, but this association is driven by children with neurodevelopmental como

Updated on:March 20,2024

Research explores environmental pollutant BPA and asthma susceptibility in mice

by PNAS NexusTransmission electron microscopy images demonstrating the effects of BPA on E. coli LPS. Credit: Wang et al.The "hygiene hypothesis" posits that allergic asthma can be triggered

Updated on: January 28,2024

Research explores environmental pollutant BPA and asthma susceptibility in mice

by PNAS NexusTransmission electron microscopy images demonstrating the effects of BPA on E. coli LPS. Credit: Wang et al.The "hygiene hypothesis" posits that allergic asthma can be triggered

Updated on:January 28,2024

Molecule can quickly, and briefly, boost white blood cell counts

by Yale UniversityCredit: Pixabay/CC0 Public DomainTreatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, a critical part of the body's immu

Updated on: March 07,2024

Molecule can quickly, and briefly, boost white blood cell counts

by Yale UniversityCredit: Pixabay/CC0 Public DomainTreatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, a critical part of the body's immu

Updated on:March 07,2024

Multifactorial mechanisms underlie leg weakness in hip OA

Multiple factors contribute to leg weakness in people with hip osteoarthritis, with muscle atrophy being the strongest contributor, according to the results of a systematic review published online Jul

Updated on: April 08,2024

Multifactorial mechanisms underlie leg weakness in hip OA

Multiple factors contribute to leg weakness in people with hip osteoarthritis, with muscle atrophy being the strongest contributor, according to the results of a systematic review published online Jul

Updated on:April 08,2024

Dissecting the genetic factors involved in systemic lupus erythematosus development

by University of TsukubaCredit: AI-generated imageSystemic lupus erythematosus (SLE) is a typical autoimmune rheumatic disease. This multifactorial condition results from a combination of multipl

Updated on: June 06,2024

Dissecting the genetic factors involved in systemic lupus erythematosus development

by University of TsukubaCredit: AI-generated imageSystemic lupus erythematosus (SLE) is a typical autoimmune rheumatic disease. This multifactorial condition results from a combination of multipl

Updated on:June 06,2024

Having hypermobile joints may increase the risk for depression and anxiety in adolescents

by University of SussexPrevalence of generalized joint hypermobility. (A) Shows the difference in prevalence of GJH in participants who meet diagnostic criteria for ICD-10 depression (blue bar) a

Updated on: May 13,2024

Having hypermobile joints may increase the risk for depression and anxiety in adolescents

by University of SussexPrevalence of generalized joint hypermobility. (A) Shows the difference in prevalence of GJH in participants who meet diagnostic criteria for ICD-10 depression (blue bar) a

Updated on:May 13,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024

What do you know about rheumatic diseases?

by Laurel Kelly, Mayo Clinic News NetworkCredit: CC0 Public DomainSeptember is Rheumatic Disease Awareness Month, which makes this a good time to learn about four common rheumatic diseases: Ankylosing

Updated on: June 26,2024

What do you know about rheumatic diseases?

by Laurel Kelly, Mayo Clinic News NetworkCredit: CC0 Public DomainSeptember is Rheumatic Disease Awareness Month, which makes this a good time to learn about four common rheumatic diseases: Ankylosing

Updated on:June 26,2024

7.6 percent of global population had osteoarthritis in 2020

by Elana GotkineThe global burden of osteoarthritis has increased since 1990 and is projected to continue increasing, according to a study published online Aug. 21 inThe Lancet Rheumatology.Jaim

Updated on: May 29,2024

7.6 percent of global population had osteoarthritis in 2020

by Elana GotkineThe global burden of osteoarthritis has increased since 1990 and is projected to continue increasing, according to a study published online Aug. 21 inThe Lancet Rheumatology.Jaim

Updated on:May 29,2024

Scientists discover a rare missense variant in STAT6 that protects against asthma

by deCODE geneticsp.L406P is a partial LOF variant. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.10.002Scientists at deCODE genetics and collaborators

Updated on: November 22,2024

Scientists discover a rare missense variant in STAT6 that protects against asthma

by deCODE geneticsp.L406P is a partial LOF variant. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.10.002Scientists at deCODE genetics and collaborators

Updated on:November 22,2024

Urate transporter structures reveal the mechanism behind important drug target for gout

bySt. Jude Children's Research HospitalCryo-EM structures of human URAT1 in different functional states. Credit:Cell Research(2024). DOI: 10.1038/s41422-024-01023-1Scientists at

Updated on: September 15,2024

Urate transporter structures reveal the mechanism behind important drug target for gout

bySt. Jude Children's Research HospitalCryo-EM structures of human URAT1 in different functional states. Credit:Cell Research(2024). DOI: 10.1038/s41422-024-01023-1Scientists at

Updated on:September 15,2024