New drug could unlock benefits of immunotherapy for more patients

FEBRUARY 27, 2024byInstitute of Cancer ResearchAntitumor responses. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI175369A new drug could offer a powerful way to sen

Updated on: March 25,2024 11

New drug could unlock benefits of immunotherapy for more patients

FEBRUARY 27, 2024byInstitute of Cancer ResearchAntitumor responses. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI175369A new drug could offer a powerful way to sen

Updated on:March 25,2024 11

Newly developed inhibitor shows potential for prostate cancer

JANUARY 9, 2024byAlbert Ludwigs University of FreiburgIdentification of a bi-substrate inhibitor of KMT9.aChemical structure of compound1awith predicted binding mode.&nbs

Updated on: March 25,2024 2

Newly developed inhibitor shows potential for prostate cancer

JANUARY 9, 2024byAlbert Ludwigs University of FreiburgIdentification of a bi-substrate inhibitor of KMT9.aChemical structure of compound1awith predicted binding mode.&nbs

Updated on:March 25,2024 2

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph

Updated on: March 25,2024 7

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph

Updated on:March 25,2024 7

Novel treatment shows promise against rare cancer in kids

by Carla K. JohnsonThis December 1993 microscope photo provided by the National Cancer Institute shows a typical neuroblastoma with rosette formation. In a study published Wednesday, April 5, 2023, in

Updated on: March 25,2024 12

Novel treatment shows promise against rare cancer in kids

by Carla K. JohnsonThis December 1993 microscope photo provided by the National Cancer Institute shows a typical neuroblastoma with rosette formation. In a study published Wednesday, April 5, 2023, in

Updated on:March 25,2024 12

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on: March 25,2024 10

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on:March 25,2024 10

A new approach for bolstering the ability of T cells to fight cancer

by Monash UniversityCredit: CC0 Public DomainA collaborative study led by the Monash Biomedicine Discovery Institute (BDI) has discovered a new immune checkpoint that may be exploited for cancer

Updated on: March 25,2024 10

A new approach for bolstering the ability of T cells to fight cancer

by Monash UniversityCredit: CC0 Public DomainA collaborative study led by the Monash Biomedicine Discovery Institute (BDI) has discovered a new immune checkpoint that may be exploited for cancer

Updated on:March 25,2024 10

Treatment of aggressive breast cancer: Discovery of a new protein involved in the development of metastases

JANUARY 31, 2024byCNRSIllustration of the invasive capacity of breast cancer cells with (on) and without (off) SMYD2 expression; Scale bar: 10µm. Credit: Casanova et al.A protein found abundantl

Updated on: March 25,2024 8

Treatment of aggressive breast cancer: Discovery of a new protein involved in the development of metastases

JANUARY 31, 2024byCNRSIllustration of the invasive capacity of breast cancer cells with (on) and without (off) SMYD2 expression; Scale bar: 10µm. Credit: Casanova et al.A protein found abundantl

Updated on:March 25,2024 8

Special RNA shown to suppress the formation of breast cancer cells

JANUARY 16, 2024by Sebastian Hollstein,Friedrich Schiller University of JenaCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2023.113644Breast cancer is the most common cancer in wom

Updated on: March 25,2024 9

Special RNA shown to suppress the formation of breast cancer cells

JANUARY 16, 2024by Sebastian Hollstein,Friedrich Schiller University of JenaCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2023.113644Breast cancer is the most common cancer in wom

Updated on:March 25,2024 9

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on: March 25,2024 6

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on:March 25,2024 6

A peptide-drug conjugate that targets the acidic environment of cancer cells may improve the efficacy of immunotherapy

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA peptide-drug conjugate that targets the acidic environment of cancer cells enhanced the efficacy of immune checkpoint

Updated on: March 25,2024 18

A peptide-drug conjugate that targets the acidic environment of cancer cells may improve the efficacy of immunotherapy

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA peptide-drug conjugate that targets the acidic environment of cancer cells enhanced the efficacy of immune checkpoint

Updated on:March 25,2024 18

Development of a novel bispecific antibody therapy to overcome myeloma heterogeneity

by Ehime UniversityMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Multiple myeloma is still an incurable hematological ma

Updated on: March 25,2024 18

Development of a novel bispecific antibody therapy to overcome myeloma heterogeneity

by Ehime UniversityMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Multiple myeloma is still an incurable hematological ma

Updated on:March 25,2024 18

A new therapeutic target turns the immune system against lymphoma

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainNon-Hodgkin's lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the im

Updated on: March 25,2024 17

A new therapeutic target turns the immune system against lymphoma

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainNon-Hodgkin's lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the im

Updated on:March 25,2024 17