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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T

Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T
Scientists glue two proteins together, driving cancer cells to self-destruct

Scientists glue two proteins together, driving cancer cells to self-destruct

by Rachel Tompa,Stanford University Medical CenterTurning kinase inhibitors into activators of therapeutic genes. Credit:Science(2024). DOI: 10.1126/science.adl5361Our bodies divest

Scientists glue two proteins together, driving cancer cells to self-destruct

by Rachel Tompa,Stanford University Medical CenterTurning kinase inhibitors into activators of therapeutic genes. Credit:Science(2024). DOI: 10.1126/science.adl5361Our bodies divest
New CAR-T cells offer on-demand control for cancer treatment

New CAR-T cells offer on-demand control for cancer treatment

byLudwig Cancer ResearchCredit: Pixabay/CC0 Public DomainLudwig Cancer Research scientists have devised new types of chimeric antigen-receptor (CAR) T cells—a type of cancer immunotherapy—that c

New CAR-T cells offer on-demand control for cancer treatment

byLudwig Cancer ResearchCredit: Pixabay/CC0 Public DomainLudwig Cancer Research scientists have devised new types of chimeric antigen-receptor (CAR) T cells—a type of cancer immunotherapy—that c
Researchers unveil inhibition mechanism of receptors on natural killer cells

Researchers unveil inhibition mechanism of receptors on natural killer cells

byUniversity of Science and Technology of ChinaSchematics of GPR34 regulating ILC1 function during tumor progression and suppression. Credit: Prof. Zhou's teamA research team led by Prof. Zh

Researchers unveil inhibition mechanism of receptors on natural killer cells

byUniversity of Science and Technology of ChinaSchematics of GPR34 regulating ILC1 function during tumor progression and suppression. Credit: Prof. Zhou's teamA research team led by Prof. Zh
Pembrolizumab aids survival with high-risk endometrial cancer

Pembrolizumab aids survival with high-risk endometrial cancer

by Lori SolomonPembrolizumab plus chemotherapy improves disease-free survival (DFS) in patients with high-risk endometrial cancer after surgery with curative intent, according to a study published onl

Pembrolizumab aids survival with high-risk endometrial cancer

by Lori SolomonPembrolizumab plus chemotherapy improves disease-free survival (DFS) in patients with high-risk endometrial cancer after surgery with curative intent, according to a study published onl
Immune cell discovery offers new potential for cancer immunotherapy

Immune cell discovery offers new potential for cancer immunotherapy

byEmory UniversityProposed models of T cell differentiation states in TDLNs. Credit:Nature(2024). DOI: 10.1038/s41586-024-08076-7Researchers at Winship Cancer Institute of Emory Univ

Immune cell discovery offers new potential for cancer immunotherapy

byEmory UniversityProposed models of T cell differentiation states in TDLNs. Credit:Nature(2024). DOI: 10.1038/s41586-024-08076-7Researchers at Winship Cancer Institute of Emory Univ
Researchers discover key genetic mutations in bowel cancer cells that lead to resistance to WRN inhibitors

Researchers discover key genetic mutations in bowel cancer cells that lead to resistance to WRN inhibitors

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainResearchers have discovered key mutations in certain cancer cells that make them resistant to WRN inhibit

Researchers discover key genetic mutations in bowel cancer cells that lead to resistance to WRN inhibitors

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainResearchers have discovered key mutations in certain cancer cells that make them resistant to WRN inhibit
Unlocking the potential of bispecific antibody-drug conjugates for targeted cancer therapy

Unlocking the potential of bispecific antibody-drug conjugates for targeted cancer therapy

by Frontiers JournalsCredit: Unsplash/CC0 Public DomainAntibody-drug conjugates (ADCs) have emerged as a promising approach in cancer therapy, offering a 'magic bullet' strategy that combines

Unlocking the potential of bispecific antibody-drug conjugates for targeted cancer therapy

by Frontiers JournalsCredit: Unsplash/CC0 Public DomainAntibody-drug conjugates (ADCs) have emerged as a promising approach in cancer therapy, offering a 'magic bullet' strategy that combines
Metformin for rare skin cancer treatment: Research shows drug's unique ability to impact immune pathways

Metformin for rare skin cancer treatment: Research shows drug's unique ability to impact immune pathways

by Tsinghua University PressThis schematic illustrates the process of developing patient-derived skin tumor organoids from Dermatofibrosarcoma Protuberans (DFSP). The workflow includes organoid cultur

Metformin for rare skin cancer treatment: Research shows drug's unique ability to impact immune pathways

by Tsinghua University PressThis schematic illustrates the process of developing patient-derived skin tumor organoids from Dermatofibrosarcoma Protuberans (DFSP). The workflow includes organoid cultur
Cancer detection recovered following pandemic disruptions

Cancer detection recovered following pandemic disruptions

by Lori SolomonOverall, cancer detection in the United States recovered meaningfully in 2021 following substantial disruptions in 2020, according to a studypublishedonline Oct. 14 in

Cancer detection recovered following pandemic disruptions

by Lori SolomonOverall, cancer detection in the United States recovered meaningfully in 2021 following substantial disruptions in 2020, according to a studypublishedonline Oct. 14 in
Polyploidy study reveals why some cancers are resistant to therapeutic drugs

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea
Performance in physical tests can help manage treatment for metastatic lung cancer

Performance in physical tests can help manage treatment for metastatic lung cancer

byFAPESPCredit: Unsplash/CC0 Public DomainA study of patients with metastatic lung cancer by researchers based in Brazil and the United States has found that their performance in simple physical

Performance in physical tests can help manage treatment for metastatic lung cancer

byFAPESPCredit: Unsplash/CC0 Public DomainA study of patients with metastatic lung cancer by researchers based in Brazil and the United States has found that their performance in simple physical