Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on: May 23,2024 3

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on:May 23,2024 3

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on: May 23,2024 6

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on:May 23,2024 6

Drug combo heralds major shift in chronic lymphocytic leukemia treatment

by Stanford University Medical CenterCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteA combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and ali

Updated on: May 23,2024 4

Drug combo heralds major shift in chronic lymphocytic leukemia treatment

by Stanford University Medical CenterCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteA combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and ali

Updated on:May 23,2024 4

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024 5

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024 5

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth

Updated on: May 23,2024 7

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth

Updated on:May 23,2024 7

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish

Updated on: May 23,2024 3

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish

Updated on:May 23,2024 3

Promise of liquid biopsy in cancer biomarker detection and prenatal screening

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersThe promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of canc

Updated on: May 23,2024 4

Promise of liquid biopsy in cancer biomarker detection and prenatal screening

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersThe promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of canc

Updated on:May 23,2024 4

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel

Updated on: May 23,2024 7

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel

Updated on:May 23,2024 7

Global study predicts more than 50 percent rise in chemotherapy demand by 2040

byLancetCredit: CC0 Public DomainTo deliver optimal treatment by 2040, a significant expansion of the chemotherapy workforce is needed.Between 2018 and 2040, the number of patients requiri

Updated on: May 23,2024 6

Global study predicts more than 50 percent rise in chemotherapy demand by 2040

byLancetCredit: CC0 Public DomainTo deliver optimal treatment by 2040, a significant expansion of the chemotherapy workforce is needed.Between 2018 and 2040, the number of patients requiri

Updated on:May 23,2024 6

A liquid biopsy test can identify patients who may respond to immune checkpoint blockade

by American Association for Cancer ResearchCredit: CC0 Public DomainA new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it co

Updated on: May 23,2024 8

A liquid biopsy test can identify patients who may respond to immune checkpoint blockade

by American Association for Cancer ResearchCredit: CC0 Public DomainA new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it co

Updated on:May 23,2024 8

Liquid biopsies reveal genetic alterations linked to cancer drug resistance

by Nicole Davis,Broad Institute of MIT and HarvardCredit: CC0 Public DomainMany patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolv

Updated on: May 23,2024 4

Liquid biopsies reveal genetic alterations linked to cancer drug resistance

by Nicole Davis,Broad Institute of MIT and HarvardCredit: CC0 Public DomainMany patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolv

Updated on:May 23,2024 4

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on: May 23,2024 6

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on:May 23,2024 6