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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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A new drug target identified for diseases associated with leukemia-causing virus

A new drug target identified for diseases associated with leukemia-causing virus

by Christine Yu,Pennsylvania State UniversityKDR inhibition induces autophagic/lysosomal degradation of Tax. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-49737-5A team

A new drug target identified for diseases associated with leukemia-causing virus

by Christine Yu,Pennsylvania State UniversityKDR inhibition induces autophagic/lysosomal degradation of Tax. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-49737-5A team
Distinct signaling pathway identified as key driver for epithelial cancer development

Distinct signaling pathway identified as key driver for epithelial cancer development

by Kurt Bodenmüller,University of ZurichSide section of the skin with epidermal stem cells (green) with one particular clone in red. Cell nuclei are stained in blue, the white dashed lines indic

Distinct signaling pathway identified as key driver for epithelial cancer development

by Kurt Bodenmüller,University of ZurichSide section of the skin with epidermal stem cells (green) with one particular clone in red. Cell nuclei are stained in blue, the white dashed lines indic
Scientists develop first bone marrow model that supports human stem cells

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first
Researchers discuss HER2-low and HER2-zero in breast cancer

Researchers discuss HER2-low and HER2-zero in breast cancer

by Impact Journals LLCMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. Credit: Nephron/WikipediaA new editorial paper titled &quot

Researchers discuss HER2-low and HER2-zero in breast cancer

by Impact Journals LLCMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. Credit: Nephron/WikipediaA new editorial paper titled &quot
Eliminating senescent cells could help treat breast, pancreatic cancers

Eliminating senescent cells could help treat breast, pancreatic cancers

byWashington University in St. LouisShown is a human breast tumor sample. The white arrows point to senescent cells in the tumor. Eliminating senescent cells, which drive inflammation, could bec

Eliminating senescent cells could help treat breast, pancreatic cancers

byWashington University in St. LouisShown is a human breast tumor sample. The white arrows point to senescent cells in the tumor. Eliminating senescent cells, which drive inflammation, could bec
Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven
Testosterone therapy may protect against breast cancer in trans masculine individuals

Testosterone therapy may protect against breast cancer in trans masculine individuals

by Jacqueline Mitchell,Beth Israel Deaconess Medical Centera) Lobular atrophy was assessed by the pathologists using four categories. b) The duration of testosterone therapy (TT) significantly c

Testosterone therapy may protect against breast cancer in trans masculine individuals

by Jacqueline Mitchell,Beth Israel Deaconess Medical Centera) Lobular atrophy was assessed by the pathologists using four categories. b) The duration of testosterone therapy (TT) significantly c
Tumor-infiltrating lymphocyte therapy marks a milestone in cancer treatment, researchers say

Tumor-infiltrating lymphocyte therapy marks a milestone in cancer treatment, researchers say

byH. Lee Moffitt Cancer Center & Research InstituteCancer cell during cell division. Credit: National Institutes of HealthThe recent U.S. Food and Drug Administration approval of lifileucel,

Tumor-infiltrating lymphocyte therapy marks a milestone in cancer treatment, researchers say

byH. Lee Moffitt Cancer Center & Research InstituteCancer cell during cell division. Credit: National Institutes of HealthThe recent U.S. Food and Drug Administration approval of lifileucel,
Long-term results from testicular cancer treatment are positive, study shows

Long-term results from testicular cancer treatment are positive, study shows

byUniversity College CorkCredit: Pixabay/CC0 Public DomainA new study shows that by combining different chemotherapy drugs, testicular cancer remains highly treatable and often curable, even aft

Long-term results from testicular cancer treatment are positive, study shows

byUniversity College CorkCredit: Pixabay/CC0 Public DomainA new study shows that by combining different chemotherapy drugs, testicular cancer remains highly treatable and often curable, even aft
Computational tool integrates transcriptomic data to enhance breast cancer diagnosis and treatment

Computational tool integrates transcriptomic data to enhance breast cancer diagnosis and treatment

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneClinical validation of EMBER. Credit:npj Breast Cancer(2024). DOI: 10.1038/s41523-024-00665-zAddressing problems with diag

Computational tool integrates transcriptomic data to enhance breast cancer diagnosis and treatment

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneClinical validation of EMBER. Credit:npj Breast Cancer(2024). DOI: 10.1038/s41523-024-00665-zAddressing problems with diag
Ophthalmologic manifestations of acute leukemia are heterogeneous

Ophthalmologic manifestations of acute leukemia are heterogeneous

by Elana GotkineOphthalmologic manifestations of acute leukemia are heterogeneous and detectable at initial presentation or relapse, according to a studypublishedonline July 10 in the&nbsp

Ophthalmologic manifestations of acute leukemia are heterogeneous

by Elana GotkineOphthalmologic manifestations of acute leukemia are heterogeneous and detectable at initial presentation or relapse, according to a studypublishedonline July 10 in the&nbsp