Study identifies molecular differences between primary breast cancer and its metastases

by UNC Lineberger Comprehensive Cancer CenterStudy design and global genomic patterns of metastatic breast tumors. a, Cohort description of the AURORA Metastatic Project. b, Diagram of the shared

Updated on: February 20,2024

Study identifies molecular differences between primary breast cancer and its metastases

by UNC Lineberger Comprehensive Cancer CenterStudy design and global genomic patterns of metastatic breast tumors. a, Cohort description of the AURORA Metastatic Project. b, Diagram of the shared

Updated on:February 20,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on: February 18,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on:February 18,2024

Drug combo breaks down cancer resistance to immunotherapy

by Ecole Polytechnique Federale de LausanneA schematic summary of the study. Credit: Douglas Hanahan (EPFL)Immunotherapy is a way of treating cancer by reprogramming the patient's immune syst

Updated on: February 23,2024

Drug combo breaks down cancer resistance to immunotherapy

by Ecole Polytechnique Federale de LausanneA schematic summary of the study. Credit: Douglas Hanahan (EPFL)Immunotherapy is a way of treating cancer by reprogramming the patient's immune syst

Updated on:February 23,2024

Trials supporting FDA approval of breakthrough drugs examined

(HealthDay)—Pivotal trials supporting U.S. Food and Drug Administration approvals granted Breakthrough Therapy designation often lack randomization, double-blinding, and control groups, according to a

Updated on: April 14,2024

Trials supporting FDA approval of breakthrough drugs examined

(HealthDay)—Pivotal trials supporting U.S. Food and Drug Administration approvals granted Breakthrough Therapy designation often lack randomization, double-blinding, and control groups, according to a

Updated on:April 14,2024

New way to target cancer's diversity and evolution

by Institute of Cancer ResearchCredit: CC0 Public DomainScientists have revealed close-up details of a vital molecule involved in the mix and match of genetic information within cells—opening up

Updated on: April 14,2024

New way to target cancer's diversity and evolution

by Institute of Cancer ResearchCredit: CC0 Public DomainScientists have revealed close-up details of a vital molecule involved in the mix and match of genetic information within cells—opening up

Updated on:April 14,2024

New immune system understanding may help doctors target cancer

by Garth Sundem,CU Anschutz Medical CampusPaul Norman, PhD. Credit: University of Colorado Cancer CenterYour immune system's natural killer cells recognize and attack two major kinds of dang

Updated on: March 12,2024

New immune system understanding may help doctors target cancer

by Garth Sundem,CU Anschutz Medical CampusPaul Norman, PhD. Credit: University of Colorado Cancer CenterYour immune system's natural killer cells recognize and attack two major kinds of dang

Updated on:March 12,2024

Treatment to a T? Taking a 'BiTE' out of lung cancer

by Osaka UniversityThe team measured the T-lymphocyte cytotoxicity against tumor cell lines using a molecule that binds to both T lymphocytes and tumor cell lines. Credit: Osaka UniversityImmune

Updated on: March 01,2024

Treatment to a T? Taking a 'BiTE' out of lung cancer

by Osaka UniversityThe team measured the T-lymphocyte cytotoxicity against tumor cell lines using a molecule that binds to both T lymphocytes and tumor cell lines. Credit: Osaka UniversityImmune

Updated on:March 01,2024

Team studies association between tumor mutations and meningioma recurrence in Grade I/II disease

by Impact JournalsAdjusted progression-free survival hazard ratios for genes examined. Credit: 2022 Dullea et al.A new research paper titled "Association between tumor mutations and meningioma re

Updated on: February 03,2024

Team studies association between tumor mutations and meningioma recurrence in Grade I/II disease

by Impact JournalsAdjusted progression-free survival hazard ratios for genes examined. Credit: 2022 Dullea et al.A new research paper titled "Association between tumor mutations and meningioma re

Updated on:February 03,2024

Researchers identified a protein associated with breast cancer

by Cathy Frisinger,UT Southwestern Medical CenterDr. Yingfei Wang says depleting the protein ZMYND8 blocks the growth of new blood vessels in breast cancer. Credit: UT Southwestern Medical Cente

Updated on: June 19,2024

Researchers identified a protein associated with breast cancer

by Cathy Frisinger,UT Southwestern Medical CenterDr. Yingfei Wang says depleting the protein ZMYND8 blocks the growth of new blood vessels in breast cancer. Credit: UT Southwestern Medical Cente

Updated on:June 19,2024

Genetic variation explains racial disparity in esophageal cancer cases

by University of California - San DiegoCredit: Pradipta Ghosh et al,JCI Insight(2022). DOI: 10.1172/jci.insight.161334Esophageal adenocarcinoma (EAC) is a type of cancer affecting the

Updated on: February 18,2024

Genetic variation explains racial disparity in esophageal cancer cases

by University of California - San DiegoCredit: Pradipta Ghosh et al,JCI Insight(2022). DOI: 10.1172/jci.insight.161334Esophageal adenocarcinoma (EAC) is a type of cancer affecting the

Updated on:February 18,2024

Discovery of hybrid cancer cells reveals how disease spreads

by Aisling Irwin, From Horizon Magazine,Horizon: The EU Research & Innovation MagazineStudies show that hybrid cancer cells (in yellow) combine properties of different cells which can make t

Updated on: May 05,2024

Discovery of hybrid cancer cells reveals how disease spreads

by Aisling Irwin, From Horizon Magazine,Horizon: The EU Research & Innovation MagazineStudies show that hybrid cancer cells (in yellow) combine properties of different cells which can make t

Updated on:May 05,2024

ASCO: undertreatment seen for women with head and neck cancer

(HealthDay)—Females with head and neck cancer (HNC) are less likely to receive intensive chemotherapy and radiation, and have an increased relative risk for death from HNC versus other causes, accordi

Updated on: March 30,2024

ASCO: undertreatment seen for women with head and neck cancer

(HealthDay)—Females with head and neck cancer (HNC) are less likely to receive intensive chemotherapy and radiation, and have an increased relative risk for death from HNC versus other causes, accordi

Updated on:March 30,2024