Team publishes new study on murine model for human early/immature T-cell precursor acute lymphoblastic leukemia

by Impact Journals LLCFigure 1 (truncated): Idh2R140Q/NHD13 double transgenic mice develop EITP ALL resembling the human disease. Credit: 2022 Negi and AplanA new research perspective titled "A m

Updated on: January 07,2024

Team publishes new study on murine model for human early/immature T-cell precursor acute lymphoblastic leukemia

by Impact Journals LLCFigure 1 (truncated): Idh2R140Q/NHD13 double transgenic mice develop EITP ALL resembling the human disease. Credit: 2022 Negi and AplanA new research perspective titled "A m

Updated on:January 07,2024

Numbers count in the genetics of moles and melanomas

by University of QueenslandReticular naevi pattern (left) Gene variations: MTAP, PLA2G6, MITF. Globular naevi pattern (right) Gene variations: IRF4. Credit: University of QueenslandUniversity of

Updated on: April 20,2024

Numbers count in the genetics of moles and melanomas

by University of QueenslandReticular naevi pattern (left) Gene variations: MTAP, PLA2G6, MITF. Globular naevi pattern (right) Gene variations: IRF4. Credit: University of QueenslandUniversity of

Updated on:April 20,2024

Inflammatory-nutritional score helps predict survival in new multiple myeloma

by Elana GotkineFor patients with newly diagnosed multiple myeloma (NDMM), a nomogram based on the inflammatory-nutritional score (INS) may help to predict survival, according to a study published onl

Updated on: January 16,2024

Inflammatory-nutritional score helps predict survival in new multiple myeloma

by Elana GotkineFor patients with newly diagnosed multiple myeloma (NDMM), a nomogram based on the inflammatory-nutritional score (INS) may help to predict survival, according to a study published onl

Updated on:January 16,2024

Drug form of traditional Chinese medicine compound found to improve survival of mice with brain tumors

by Brown UniversityGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101019A new study shows how a drug made from a natural compound used in traditional

Updated on: January 30,2024

Drug form of traditional Chinese medicine compound found to improve survival of mice with brain tumors

by Brown UniversityGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101019A new study shows how a drug made from a natural compound used in traditional

Updated on:January 30,2024

Exercise could reduce frailty in the most common form of leukemia

by University of SurreyCredit: Pixabay/CC0 Public DomainIncreased levels of exercise could help reduce frailty in patients with the most common form of leukemia, chronic lymphocytic (CLL), accord

Updated on: January 29,2024

Exercise could reduce frailty in the most common form of leukemia

by University of SurreyCredit: Pixabay/CC0 Public DomainIncreased levels of exercise could help reduce frailty in patients with the most common form of leukemia, chronic lymphocytic (CLL), accord

Updated on:January 29,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on: January 22,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on:January 22,2024

Researchers invent a new class of AI to improve cancer research and treatments

by Colette Gallagher,Mayo ClinicCredit: Mayo ClinicMayo Clinic researchers recently invented a new class of artificial intelligence (AI) algorithms called hypothesis-driven AI that are a signifi

Updated on: March 20,2024

Researchers invent a new class of AI to improve cancer research and treatments

by Colette Gallagher,Mayo ClinicCredit: Mayo ClinicMayo Clinic researchers recently invented a new class of artificial intelligence (AI) algorithms called hypothesis-driven AI that are a signifi

Updated on:March 20,2024

Direct-acting antivirals still underused in hep C-related liver cancer

by Lori SolomonDirect-acting antiviral agents (DAAs) remain underutilized in patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), according to a study presented at The Liver M

Updated on: April 10,2024

Direct-acting antivirals still underused in hep C-related liver cancer

by Lori SolomonDirect-acting antiviral agents (DAAs) remain underutilized in patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), according to a study presented at The Liver M

Updated on:April 10,2024

Mechanism identified for drug resistance in glioblastoma brain tumors

by Sarah Avery,Duke UniversityPro-tumor immune programming in the glioma microenvironment is CaMKK2 dependent. a Schematic depicting scRNA-seq experimental design. n = 4 WT and CaMKK2 KO mice ha

Updated on: January 02,2024

Mechanism identified for drug resistance in glioblastoma brain tumors

by Sarah Avery,Duke UniversityPro-tumor immune programming in the glioma microenvironment is CaMKK2 dependent. a Schematic depicting scRNA-seq experimental design. n = 4 WT and CaMKK2 KO mice ha

Updated on:January 02,2024

Cancer drug insight tactic could spell double trouble for tumours

by University of EdinburghScientists hope to identify cancer drugs that work in a two-pronged approach -- by inducing errors when cancer cells divide packages of their DNA -- known as chromosomes

Updated on: March 08,2024

Cancer drug insight tactic could spell double trouble for tumours

by University of EdinburghScientists hope to identify cancer drugs that work in a two-pronged approach -- by inducing errors when cancer cells divide packages of their DNA -- known as chromosomes

Updated on:March 08,2024

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on: March 30,2024

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on:March 30,2024

Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on: February 18,2024

Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on:February 18,2024