Drug combo ups progression-free survival for metastatic prostate cancer

by Elana GotkineFor patients with metastatic castration-resistant prostate cancer (mCRPC), talazoparib plus enzalutamide results in improvement in radiographic progression-free survival (rPFS), accord

Updated on: January 30,2024

Drug combo ups progression-free survival for metastatic prostate cancer

by Elana GotkineFor patients with metastatic castration-resistant prostate cancer (mCRPC), talazoparib plus enzalutamide results in improvement in radiographic progression-free survival (rPFS), accord

Updated on:January 30,2024

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on: February 18,2024

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on:February 18,2024

The origin-of-life molecule, a key to cancer research

byUniversity of SevilleSchematic model of the regulation and role of RNAPII-generated nascent RNA to guide DNA end resection and DSB repair by HR. Credit:Nature Communications(2022).

Updated on: January 04,2024

The origin-of-life molecule, a key to cancer research

byUniversity of SevilleSchematic model of the regulation and role of RNAPII-generated nascent RNA to guide DNA end resection and DSB repair by HR. Credit:Nature Communications(2022).

Updated on:January 04,2024

New study links genetic diversity of tumors with resistance to treatment in Asian lung cancer patients

by Agency for Science, Technology and Research (A*STAR), SingaporeResearchers from Singapore discovered that the EGFR mutant lung cancer in Asians is more varied than its counterpart observed in

Updated on: March 08,2024

New study links genetic diversity of tumors with resistance to treatment in Asian lung cancer patients

by Agency for Science, Technology and Research (A*STAR), SingaporeResearchers from Singapore discovered that the EGFR mutant lung cancer in Asians is more varied than its counterpart observed in

Updated on:March 08,2024

Restoring the gut biome after antibiotics could lead to better outcomes for ovarian cancer patients

by Cleveland ClinicCredit: Pixabay/CC0 Public DomainAntibiotics routinely used in ovarian cancer care indiscriminately kill gut bacteria, leading to faster cancer progression and lower survival r

Updated on: January 30,2024

Restoring the gut biome after antibiotics could lead to better outcomes for ovarian cancer patients

by Cleveland ClinicCredit: Pixabay/CC0 Public DomainAntibiotics routinely used in ovarian cancer care indiscriminately kill gut bacteria, leading to faster cancer progression and lower survival r

Updated on:January 30,2024

Researchers generate lab-grown human tissue model for food tube cancer

by Johns Hopkins University School of MedicineHuman gastroesophageal junction-derived organoid, modified by dual-knockout of key tumor suppressor genes (TP53/CDKN2A) using CRISPR/Cas9 gene editin

Updated on: February 03,2024

Researchers generate lab-grown human tissue model for food tube cancer

by Johns Hopkins University School of MedicineHuman gastroesophageal junction-derived organoid, modified by dual-knockout of key tumor suppressor genes (TP53/CDKN2A) using CRISPR/Cas9 gene editin

Updated on:February 03,2024

Overall burden of tumor genome changes can predict patient outcomes

by eLifeKiller T cells surround a cancer cell. Credit: NIHResearchers have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types

Updated on: April 09,2024

Overall burden of tumor genome changes can predict patient outcomes

by eLifeKiller T cells surround a cancer cell. Credit: NIHResearchers have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types

Updated on:April 09,2024

Numbers count in the genetics of moles and melanomas

by University of QueenslandReticular naevi pattern (left) Gene variations: MTAP, PLA2G6, MITF. Globular naevi pattern (right) Gene variations: IRF4. Credit: University of QueenslandUniversity of

Updated on: April 20,2024

Numbers count in the genetics of moles and melanomas

by University of QueenslandReticular naevi pattern (left) Gene variations: MTAP, PLA2G6, MITF. Globular naevi pattern (right) Gene variations: IRF4. Credit: University of QueenslandUniversity of

Updated on:April 20,2024

Blocking pro-fibrosis pathway may improve immunotherapy of metastatic breast cancer

by Massachusetts General HospitalMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/WikipediaA Massachusetts G

Updated on: April 01,2024

Blocking pro-fibrosis pathway may improve immunotherapy of metastatic breast cancer

by Massachusetts General HospitalMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/WikipediaA Massachusetts G

Updated on:April 01,2024

FAAH inhibition ameliorates murine breast cancer: Study

by Impact Journals LLCAn overview of the endocannabinoid pathway and molecules tested in this study. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28534A new research paper titled &quo

Updated on: May 11,2024

FAAH inhibition ameliorates murine breast cancer: Study

by Impact Journals LLCAn overview of the endocannabinoid pathway and molecules tested in this study. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28534A new research paper titled &quo

Updated on:May 11,2024

One test to diagnose them all: Researchers exploit cancers' unique DNA signature

by Abu Sina, Laura G. Carrascosa And Matt Trau,The ConversationCredit: AI-generated imageResearchers have developed a test that could be used to diagnose all cancers. It is based on a unique DNA

Updated on: May 07,2024

One test to diagnose them all: Researchers exploit cancers' unique DNA signature

by Abu Sina, Laura G. Carrascosa And Matt Trau,The ConversationCredit: AI-generated imageResearchers have developed a test that could be used to diagnose all cancers. It is based on a unique DNA

Updated on:May 07,2024

High levels of natural immune suppressor correlate with poor survival in the most common leukemia

by Medical College of Georgia at Augusta UniversityPatients diagnosed with the most common form of leukemia who also have high levels of an enzyme known to suppress the immune system are most lik

Updated on: April 23,2024

High levels of natural immune suppressor correlate with poor survival in the most common leukemia

by Medical College of Georgia at Augusta UniversityPatients diagnosed with the most common form of leukemia who also have high levels of an enzyme known to suppress the immune system are most lik

Updated on:April 23,2024