Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer

by Chinese Academy of SciencesCredit: CC0 Public DomainDespite the remarkable success of molecular targeted therapy in recent years, the rapid increase of drug resistance is a major obstacle to e

Updated on: April 14,2024 16

Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer

by Chinese Academy of SciencesCredit: CC0 Public DomainDespite the remarkable success of molecular targeted therapy in recent years, the rapid increase of drug resistance is a major obstacle to e

Updated on:April 14,2024 16

Discovery may bolster chemotherapy potency while protecting the heart from side-effects

by University of Alberta Faculty of Medicine & Dentistry(From left) Researchers Gopinath Sutendra and Bruno Saleme in a lab at the University of Alberta. The two have found a new therapeutic

Updated on: April 14,2024 10

Discovery may bolster chemotherapy potency while protecting the heart from side-effects

by University of Alberta Faculty of Medicine & Dentistry(From left) Researchers Gopinath Sutendra and Bruno Saleme in a lab at the University of Alberta. The two have found a new therapeutic

Updated on:April 14,2024 10

Those with the BRCA1 gene mutation may face greater risk for aggressive cancer caused by asbestos exposure

byNagoya UniversityChrysotile-induced MMs present lower expression levels of Brca1. (A) Immunohistochemistry (IHC) staining of total BRCA1 on MM samples (bar=25 μm; N≧7).

Updated on: January 02,2024 10

Those with the BRCA1 gene mutation may face greater risk for aggressive cancer caused by asbestos exposure

byNagoya UniversityChrysotile-induced MMs present lower expression levels of Brca1. (A) Immunohistochemistry (IHC) staining of total BRCA1 on MM samples (bar=25 μm; N≧7).

Updated on:January 02,2024 10

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to

Updated on: March 12,2024 11

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to

Updated on:March 12,2024 11

Private and secure generative AI tool supports operations and research in a cancer center

byDana-Farber Cancer InstituteCredit: CC0 Public DomainDana-Farber Cancer Institute has implemented an artificial intelligence (AI) application intended for general use in a medical center or ho

Updated on: March 30,2024 0

Private and secure generative AI tool supports operations and research in a cancer center

byDana-Farber Cancer InstituteCredit: CC0 Public DomainDana-Farber Cancer Institute has implemented an artificial intelligence (AI) application intended for general use in a medical center or ho

Updated on:March 30,2024 0

Investigational drug may combat brain tumors by targeting cancer cells' fat production

by Katie Marquedant,Massachusetts General HospitalCorrelation analysis between SCD expression and sensitivity to YTX-7739. (A) Immunoblot analysis (left) of SCD expression in YTX-7739-sensitive

Updated on: February 01,2024 18

Investigational drug may combat brain tumors by targeting cancer cells' fat production

by Katie Marquedant,Massachusetts General HospitalCorrelation analysis between SCD expression and sensitivity to YTX-7739. (A) Immunoblot analysis (left) of SCD expression in YTX-7739-sensitive

Updated on:February 01,2024 18

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr

Updated on: January 02,2024 10

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr

Updated on:January 02,2024 10

'Bet hedging' explains the efficacy of many combination cancer therapies

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe efficacy of many FDA-approved cancer drug combinations is not due to synergistic interactions between drugs, but rat

Updated on: March 14,2024 18

'Bet hedging' explains the efficacy of many combination cancer therapies

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe efficacy of many FDA-approved cancer drug combinations is not due to synergistic interactions between drugs, but rat

Updated on:March 14,2024 18

Researchers develop method for separating tissue types in tumor samples

by University of North Carolina at Chapel Hill School of MedicineHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirat

Updated on: June 11,2024 5

Researchers develop method for separating tissue types in tumor samples

by University of North Carolina at Chapel Hill School of MedicineHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirat

Updated on:June 11,2024 5

Molecular mechanisms regulating prostate cancer hypoxia identified

by Melissa Rohman,Northwestern UniversityMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A Northwestern Medicine

Updated on: January 02,2024 9

Molecular mechanisms regulating prostate cancer hypoxia identified

by Melissa Rohman,Northwestern UniversityMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A Northwestern Medicine

Updated on:January 02,2024 9

Cancer screening rates decline when patients see doctors later in day

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainCompared to patients who see their primary care doctor earlier in the day, cancer screening rates decline

Updated on: March 08,2024 11

Cancer screening rates decline when patients see doctors later in day

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainCompared to patients who see their primary care doctor earlier in the day, cancer screening rates decline

Updated on:March 08,2024 11

Long-term exposure to nitrates in drinking water may be a risk factor for prostate cancer

by Barcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainThe nitrate ingested over the course of a person's adult lifetime through the consumption of tap water and bottled wat

Updated on: February 18,2024 16

Long-term exposure to nitrates in drinking water may be a risk factor for prostate cancer

by Barcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainThe nitrate ingested over the course of a person's adult lifetime through the consumption of tap water and bottled wat

Updated on:February 18,2024 16