Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne

Updated on: September 07,2024

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne

Updated on:September 07,2024

Scientists develop a new model for glioblastoma using gene-edited organoids

by Salk InstituteOrganoids reveal how a deadly brain cancer grows. From left to right, tumor cells labeled with red fluorescent marker tdTomato spread in a cerebral organoid over a time period of

Updated on: March 01,2024

Scientists develop a new model for glioblastoma using gene-edited organoids

by Salk InstituteOrganoids reveal how a deadly brain cancer grows. From left to right, tumor cells labeled with red fluorescent marker tdTomato spread in a cerebral organoid over a time period of

Updated on:March 01,2024

Technology holds personalised cancer vaccine breakthrough

by Kate Zischke,University of QueenslandThe attack of a tumour cell made by white blood cells of the patient (lymphocytes) generated by cancer vaccines. Credit: University of QueenslandUniversit

Updated on: March 06,2024

Technology holds personalised cancer vaccine breakthrough

by Kate Zischke,University of QueenslandThe attack of a tumour cell made by white blood cells of the patient (lymphocytes) generated by cancer vaccines. Credit: University of QueenslandUniversit

Updated on:March 06,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on: March 30,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on:March 30,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on: March 30,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on:March 30,2024

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainBoosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to str

Updated on: February 03,2024

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainBoosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to str

Updated on:February 03,2024

Policies favoring high-volume hospitals may disadvantage rural cancer patients

by University of PittsburghCredit: Pixabay/CC0 Public DomainPatients with cancer who live in rural Pennsylvania counties appear to know that they may have better outcomes if they receive their ca

Updated on: February 03,2024

Policies favoring high-volume hospitals may disadvantage rural cancer patients

by University of PittsburghCredit: Pixabay/CC0 Public DomainPatients with cancer who live in rural Pennsylvania counties appear to know that they may have better outcomes if they receive their ca

Updated on:February 03,2024

A study refines a molecular marker that accurately predicts the recurrence of aggressive meningiomas

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainDrs. Akash Patel and Tiemo Klisch, investigators at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Childr

Updated on: February 19,2024

A study refines a molecular marker that accurately predicts the recurrence of aggressive meningiomas

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainDrs. Akash Patel and Tiemo Klisch, investigators at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Childr

Updated on:February 19,2024

Researchers share insights on the evolution of proton radiotherapy

by Mass General BrighamCredit: Unsplash/CC0 Public DomainIn a review article published inThe Lancet Oncology, Susu Yan, Ph.D., and Thomas Bortfeld, Ph.D., from the Biophysics Division of MG

Updated on: February 01,2024

Researchers share insights on the evolution of proton radiotherapy

by Mass General BrighamCredit: Unsplash/CC0 Public DomainIn a review article published inThe Lancet Oncology, Susu Yan, Ph.D., and Thomas Bortfeld, Ph.D., from the Biophysics Division of MG

Updated on:February 01,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on: February 03,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on:February 03,2024

Researchers identify enzyme that suppresses immune system in breast cancer

by Duke University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by T

Updated on: June 04,2024

Researchers identify enzyme that suppresses immune system in breast cancer

by Duke University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by T

Updated on:June 04,2024