Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

byUniversity College LondonFrameshift switching of the MSH6 C8 coding homopolymer drives stochastic loss and restoration of MSH6 expression like a molecular ON/OFF switch. Credit:Nature Ge

Updated on: July 05,2024 0

Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

byUniversity College LondonFrameshift switching of the MSH6 C8 coding homopolymer drives stochastic loss and restoration of MSH6 expression like a molecular ON/OFF switch. Credit:Nature Ge

Updated on:July 05,2024 0

Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b

Updated on: February 18,2024 20

Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b

Updated on:February 18,2024 20

'Hijacker' drives cancer in some patients with high-risk neuroblastoma

by St. Jude Children's Research HospitalThe study authors (from left) Ying Shao, Yu Liu, PhD, and John Easton, PhD. Credit: Seth Dixon / St. Jude Children's Research HospitalResearchers h

Updated on: March 13,2024 19

'Hijacker' drives cancer in some patients with high-risk neuroblastoma

by St. Jude Children's Research HospitalThe study authors (from left) Ying Shao, Yu Liu, PhD, and John Easton, PhD. Credit: Seth Dixon / St. Jude Children's Research HospitalResearchers h

Updated on:March 13,2024 19

Study validates diagnostic assay for Asian cancers

by National University of SingaporeGraphical overview of workflow and coverage of cancer subtypes in the Asian Pan-Cancer Panel. A total of six workdays are required from sample QC to reliable ge

Updated on: February 20,2024 12

Study validates diagnostic assay for Asian cancers

by National University of SingaporeGraphical overview of workflow and coverage of cancer subtypes in the Asian Pan-Cancer Panel. A total of six workdays are required from sample QC to reliable ge

Updated on:February 20,2024 12

HPV DNA identified in oral cavity of 6.2 percent of teen girls

(HealthDay)—Human papillomavirus (HPV) DNA is detected in the oral cavities of about 6.2 percent of sexually active female adolescents, according to a study published online Oct. 25 inJAMA Netwo

Updated on: May 05,2024 13

HPV DNA identified in oral cavity of 6.2 percent of teen girls

(HealthDay)—Human papillomavirus (HPV) DNA is detected in the oral cavities of about 6.2 percent of sexually active female adolescents, according to a study published online Oct. 25 inJAMA Netwo

Updated on:May 05,2024 13

A new strategy to enhance gene therapy for sickle cell disease

byMary Ann Liebert, IncCyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease. Credit: Mary Ann Liebe

Updated on: November 22,2024 0

A new strategy to enhance gene therapy for sickle cell disease

byMary Ann Liebert, IncCyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease. Credit: Mary Ann Liebe

Updated on:November 22,2024 0

Researchers discover common markers of tumor hypoxia across 19 cancer types

by Ontario Institute for Cancer ResearchUnlike healthy tissues, tumours thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despit

Updated on: June 22,2024 6

Researchers discover common markers of tumor hypoxia across 19 cancer types

by Ontario Institute for Cancer ResearchUnlike healthy tissues, tumours thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despit

Updated on:June 22,2024 6

Finances need to be a bigger part of our conversation about cancer, researchers say

by Maddie Massy-Westropp,University of New South WalesCredit: Unsplash/CC0 Public DomainWhen Jessie Oldfield was experiencing some bleeding at 23 weeks pregnant, she was worried that she had pre

Updated on: February 18,2024 17

Finances need to be a bigger part of our conversation about cancer, researchers say

by Maddie Massy-Westropp,University of New South WalesCredit: Unsplash/CC0 Public DomainWhen Jessie Oldfield was experiencing some bleeding at 23 weeks pregnant, she was worried that she had pre

Updated on:February 18,2024 17

Smoking linked to melanoma-associated death in early-stage melanoma

by Elana GotkineFor patients with clinical stage I and II melanoma, smoking is associated with an increased risk for melanoma-associated death, according to a study published online Feb. 6 inJAM

Updated on: March 05,2024 13

Smoking linked to melanoma-associated death in early-stage melanoma

by Elana GotkineFor patients with clinical stage I and II melanoma, smoking is associated with an increased risk for melanoma-associated death, according to a study published online Feb. 6 inJAM

Updated on:March 05,2024 13

Experts explore the underlying biology of cancer and potential therapeutic strategies

by Beijing Zhongke Journal Publising Co.ABBS: a special issue focused on mechanism-based studies. Credit: Beijing Zhongke Journal Publising Co. Ltd.Cancer's global impact is severe, affecting mill

Updated on: January 22,2024 19

Experts explore the underlying biology of cancer and potential therapeutic strategies

by Beijing Zhongke Journal Publising Co.ABBS: a special issue focused on mechanism-based studies. Credit: Beijing Zhongke Journal Publising Co. Ltd.Cancer's global impact is severe, affecting mill

Updated on:January 22,2024 19

Advancing neuropathology with AI-driven classification of diffuse gliomas

by Liu Jia,Chinese Academy of SciencesTen examples of classification results on the external testing sets. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41195-9Diffuse

Updated on: March 30,2024 11

Advancing neuropathology with AI-driven classification of diffuse gliomas

by Liu Jia,Chinese Academy of SciencesTen examples of classification results on the external testing sets. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41195-9Diffuse

Updated on:March 30,2024 11

Researchers design gene therapy that can effectively target glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Glioblastoma (GBM), an aggressive brain cancer, is notoriously resistant to treatment, with recurr

Updated on: June 06,2024 3

Researchers design gene therapy that can effectively target glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Glioblastoma (GBM), an aggressive brain cancer, is notoriously resistant to treatment, with recurr

Updated on:June 06,2024 3