Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre

Updated on: January 02,2024

Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre

Updated on:January 02,2024

Cervical cancer discovery offers major new clue to better understand the disease

byUniversity College LondonDifferences in the tumor microenvironment between cervical cancer subgroups. Plot showing median abundances (x-axis) and median differences (%, y-axis) for different c

Updated on: January 22,2024

Cervical cancer discovery offers major new clue to better understand the disease

byUniversity College LondonDifferences in the tumor microenvironment between cervical cancer subgroups. Plot showing median abundances (x-axis) and median differences (%, y-axis) for different c

Updated on:January 22,2024

Researchers discover possible new treatment strategy for lung cancer

by H. Lee Moffitt Cancer Center & Research InstituteLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaLung cancer is the second most common cancer found in both m

Updated on: June 22,2024

Researchers discover possible new treatment strategy for lung cancer

by H. Lee Moffitt Cancer Center & Research InstituteLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaLung cancer is the second most common cancer found in both m

Updated on:June 22,2024

Novel drug shows early promise in treating multiple myeloma

byPerelman School of Medicine at the University of PennsylvaniaMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0A first-of

Updated on: January 15,2024

Novel drug shows early promise in treating multiple myeloma

byPerelman School of Medicine at the University of PennsylvaniaMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0A first-of

Updated on:January 15,2024

Lung cancer treatment shows promise in tumor models

by UTSouthwestern Medical Center6TdG induces double stranded breaks and apoptosis in mouse tumors. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-44861-8A molecule

Updated on: March 20,2024

Lung cancer treatment shows promise in tumor models

by UTSouthwestern Medical Center6TdG induces double stranded breaks and apoptosis in mouse tumors. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-44861-8A molecule

Updated on:March 20,2024

How the body fights cancer and intruders

by Lori Dajose,California Institute of TechnologyT cells surround a cancer cell. Credit: National Institutes of HealthThe human body's immune system is like a vast team of special agents. Ce

Updated on: March 01,2024

How the body fights cancer and intruders

by Lori Dajose,California Institute of TechnologyT cells surround a cancer cell. Credit: National Institutes of HealthThe human body's immune system is like a vast team of special agents. Ce

Updated on:March 01,2024

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on: April 22,2024

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on:April 22,2024

On the trail of missing genes and cancer clues

byLa Jolla Institute for ImmunologyThe image on the left shows an eight-cell blastomere developed from mouse embryonic stem cells with normal TET function. The image on the right shows the conse

Updated on: January 16,2024

On the trail of missing genes and cancer clues

byLa Jolla Institute for ImmunologyThe image on the left shows an eight-cell blastomere developed from mouse embryonic stem cells with normal TET function. The image on the right shows the conse

Updated on:January 16,2024

Researchers discover new molecular driver of retinoblastoma

byUT Southwestern Medical CenterInactive remnant of retinoblastoma tumor following successful intra-arterial chemotherapy. Credit: UT Southwestern Medical CenterDespite decades of medical advanc

Updated on: January 30,2024

Researchers discover new molecular driver of retinoblastoma

byUT Southwestern Medical CenterInactive remnant of retinoblastoma tumor following successful intra-arterial chemotherapy. Credit: UT Southwestern Medical CenterDespite decades of medical advanc

Updated on:January 30,2024

Radon, even at levels below EPA guideline for mitigation, is linked to childhood leukemia

byOregon State UniversityGraphical abstract. Credit:Science of The Total Environment(2024). DOI: 10.1016/j.scitotenv.2024.176288A study of more than 700 counties across multiple U.S.

Updated on: November 10,2024

Radon, even at levels below EPA guideline for mitigation, is linked to childhood leukemia

byOregon State UniversityGraphical abstract. Credit:Science of The Total Environment(2024). DOI: 10.1016/j.scitotenv.2024.176288A study of more than 700 counties across multiple U.S.

Updated on:November 10,2024

Researchers map the effects of dietary nutrients on disease

by The Francis Crick InstituteResearchers gathered experimental data to put into the model by measuring the levels of gene expression in liver and liver tumours from mice that had been fed either

Updated on: February 03,2024

Researchers map the effects of dietary nutrients on disease

by The Francis Crick InstituteResearchers gathered experimental data to put into the model by measuring the levels of gene expression in liver and liver tumours from mice that had been fed either

Updated on:February 03,2024

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on: March 09,2024

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on:March 09,2024