Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on: February 20,2024

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on:February 20,2024

Final overall study analysis continues to show benefit of sacituzumab govitecan in advanced HR+ breast cancer

byDana-Farber Cancer InstituteOverall survival in the intention-to-treat population. This is the planned final analysis of overall survival in the intent-to-treat population of all randomly assi

Updated on: January 22,2024

Final overall study analysis continues to show benefit of sacituzumab govitecan in advanced HR+ breast cancer

byDana-Farber Cancer InstituteOverall survival in the intention-to-treat population. This is the planned final analysis of overall survival in the intent-to-treat population of all randomly assi

Updated on:January 22,2024

Combination of photonic sensors and microfluidics could detect cancer markers within 20 minutes

by Andrei Korshunov,Skolkovo Institute of Science and TechnologyStudy co-author and Skoltech PhD student Aleksei Kuzin posing next to a measurement stand. He is holding thephotonic chip th

Updated on: March 05,2024

Combination of photonic sensors and microfluidics could detect cancer markers within 20 minutes

by Andrei Korshunov,Skolkovo Institute of Science and TechnologyStudy co-author and Skoltech PhD student Aleksei Kuzin posing next to a measurement stand. He is holding thephotonic chip th

Updated on:March 05,2024

Study reveals possible solution to elevated cancer risk from important anti-infection drug

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainFor the last decade, medical experts have known that voriconazole, an effective antifungal m

Updated on: July 02,2024

Study reveals possible solution to elevated cancer risk from important anti-infection drug

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainFor the last decade, medical experts have known that voriconazole, an effective antifungal m

Updated on:July 02,2024

Metastasis enablers: Findings could unlock new ovarian cancer treatments

by Tom Ziemer,University of Wisconsin-MadisonBiomedical engineering professor Pam Kreeger and other lab members have teased out how one type of immune cells helps cancer cells attach in the peri

Updated on: April 01,2024

Metastasis enablers: Findings could unlock new ovarian cancer treatments

by Tom Ziemer,University of Wisconsin-MadisonBiomedical engineering professor Pam Kreeger and other lab members have teased out how one type of immune cells helps cancer cells attach in the peri

Updated on:April 01,2024

Cell division, DNA repair and cancer progression closely tied to CDK9 dysfunction

by Sbarro Health Research Organization (SHRO)CDK9 isoforms regulate DNA damage response.AWestern blot analysis of CDK9 in HeLa cells transfected with siRNA CDK9 (siCDK9) or control (siCTR)

Updated on: March 20,2024

Cell division, DNA repair and cancer progression closely tied to CDK9 dysfunction

by Sbarro Health Research Organization (SHRO)CDK9 isoforms regulate DNA damage response.AWestern blot analysis of CDK9 in HeLa cells transfected with siRNA CDK9 (siCDK9) or control (siCTR)

Updated on:March 20,2024

Liquid biopsy chip detects tumor cells in 100 percent of blood samples from breast cancer patients

by Michael W. Dorsey,Worcester Polytechnic InstituteA circulating cancer cell (pink) attaches to carbon nanotube surface; white blood cells (blue) do not adhere and are later washed away. Credit

Updated on: May 23,2024

Liquid biopsy chip detects tumor cells in 100 percent of blood samples from breast cancer patients

by Michael W. Dorsey,Worcester Polytechnic InstituteA circulating cancer cell (pink) attaches to carbon nanotube surface; white blood cells (blue) do not adhere and are later washed away. Credit

Updated on:May 23,2024

Team identifies genes that increase risk for triple-negative breast cancer

by Mayo ClinicThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is dividing. Introns are regi

Updated on: May 27,2024

Team identifies genes that increase risk for triple-negative breast cancer

by Mayo ClinicThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is dividing. Introns are regi

Updated on:May 27,2024

Circulating tumor cell count guidance may improve long-term outcomes for patients with metastatic breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainThe use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-

Updated on: January 22,2024

Circulating tumor cell count guidance may improve long-term outcomes for patients with metastatic breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainThe use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-

Updated on:January 22,2024

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on: April 22,2024

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on:April 22,2024

Antibiotics after breast cancer linked to poorer survival, study finds

by Krista Conger,Stanford University Medical CenterLandmarking analysis to evaluate the impact of antimicrobial exposure on survival over time on N = 772 independent patients. Data were presente

Updated on: January 23,2024

Antibiotics after breast cancer linked to poorer survival, study finds

by Krista Conger,Stanford University Medical CenterLandmarking analysis to evaluate the impact of antimicrobial exposure on survival over time on N = 772 independent patients. Data were presente

Updated on:January 23,2024

Sugar modifications the key to unlocking ovarian cancer secrets

byGriffith UniversityOvarian cancer research. Credit: Griffith UniversityThe ability to identify unique sugars that decorate ovarian cancer cells could help prevent the spread of cancer and impr

Updated on: January 07,2024

Sugar modifications the key to unlocking ovarian cancer secrets

byGriffith UniversityOvarian cancer research. Credit: Griffith UniversityThe ability to identify unique sugars that decorate ovarian cancer cells could help prevent the spread of cancer and impr

Updated on:January 07,2024