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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

by Science China PressThepeptide Pal-DMPOP consists a peptide inhibitor of CD47/SIRPα, a D-peptide inhibitor of PD-1/PD-L1, and a palmitic acid tail conjugated at its N-terminal through a P

Researchers synthesize chimeric peptide that elicits antitumor activity for cancer immunotherapy

by Science China PressThepeptide Pal-DMPOP consists a peptide inhibitor of CD47/SIRPα, a D-peptide inhibitor of PD-1/PD-L1, and a palmitic acid tail conjugated at its N-terminal through a P
National cancer control efforts should address the system, not its individual parts, says new report

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish
Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

byWileyCredit: CC0 Public DomainBoth acupuncture—which is invasive and involves inserted needles—and acupressure—which is non-invasive and involves mechanical pressure—can potentially help reduc

Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

byWileyCredit: CC0 Public DomainBoth acupuncture—which is invasive and involves inserted needles—and acupressure—which is non-invasive and involves mechanical pressure—can potentially help reduc
Investigating mechanisms of aggressive glioblastoma tumor growth

Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr

Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr
New drug delays progression of glioma, a deadly brain cancer, during clinical trial

New drug delays progression of glioma, a deadly brain cancer, during clinical trial

by Denise Heady,University of California, Los AngelesCredit: Unsplash/CC0 Public DomainIn an international study co-led by UCLA, scientists have shown that a new targeted therapy drug can extend

New drug delays progression of glioma, a deadly brain cancer, during clinical trial

by Denise Heady,University of California, Los AngelesCredit: Unsplash/CC0 Public DomainIn an international study co-led by UCLA, scientists have shown that a new targeted therapy drug can extend
Unique genetic signature found by research in different types of cancer

Unique genetic signature found by research in different types of cancer

by MELISA InstitutetimsTOF Pro mass spectrometer located in MELISA Institute's laboratories. Credit: MELISA InstituteResearch led by Dr. Mabel Vidal in the Department of Computer Science at the Un

Unique genetic signature found by research in different types of cancer

by MELISA InstitutetimsTOF Pro mass spectrometer located in MELISA Institute's laboratories. Credit: MELISA InstituteResearch led by Dr. Mabel Vidal in the Department of Computer Science at the Un
Researchers publish cell protein findings to determine effectiveness of immunotherapy for colon cancer

Researchers publish cell protein findings to determine effectiveness of immunotherapy for colon cancer

by Kelley Luckstein,Mayo ClinicCredit: CC0 Public DomainMayo Clinic Comprehensive Cancer Center researchers have identified key findings that can assist clinicians in predicting whether a patien

Researchers publish cell protein findings to determine effectiveness of immunotherapy for colon cancer

by Kelley Luckstein,Mayo ClinicCredit: CC0 Public DomainMayo Clinic Comprehensive Cancer Center researchers have identified key findings that can assist clinicians in predicting whether a patien
Genetic connection between aerobic fitness and disease is not what you'd expect

Genetic connection between aerobic fitness and disease is not what you'd expect

by American Physiological SocietyCredit:Physiological Genomics(2023). DOI: 10.1152/physiolgenomics.00026.2023New research examines the complex relationship between gene variants, card

Genetic connection between aerobic fitness and disease is not what you'd expect

by American Physiological SocietyCredit:Physiological Genomics(2023). DOI: 10.1152/physiolgenomics.00026.2023New research examines the complex relationship between gene variants, card
Multiple recurrent, repeat expansions found in human cancer genomes

Multiple recurrent, repeat expansions found in human cancer genomes

by Bob Yirka , Medical XpressGenome-wide detection of rREs in cancer genomes. a, Scheme of the method to identify rREs in 2,509 patients across 29 human cancer types: 1, head and neck squamous cell ca

Multiple recurrent, repeat expansions found in human cancer genomes

by Bob Yirka , Medical XpressGenome-wide detection of rREs in cancer genomes. a, Scheme of the method to identify rREs in 2,509 patients across 29 human cancer types: 1, head and neck squamous cell ca
One lung cancer drug receives NHS England approval, while another is rejected

One lung cancer drug receives NHS England approval, while another is rejected

by Cancer Research UKCredit: CC0 Public DomainA targeted drug has been accepted for routine use on the NHS in England for some adults with untreated, advanced lung cancer. But another precision d

One lung cancer drug receives NHS England approval, while another is rejected

by Cancer Research UKCredit: CC0 Public DomainA targeted drug has been accepted for routine use on the NHS in England for some adults with untreated, advanced lung cancer. But another precision d
ASH: A+CHP bests CHOP for peripheral T-cell lymphoma

ASH: A+CHP bests CHOP for peripheral T-cell lymphoma

(HealthDay)—For patients with CD30-positive peripheral T-cell lymphoma, brentuximab vedotin, cyclophosphamide, doxorubicin, and prednisone (A+CHP) is superior to cyclophosphamide, doxorubicin, vincris

ASH: A+CHP bests CHOP for peripheral T-cell lymphoma

(HealthDay)—For patients with CD30-positive peripheral T-cell lymphoma, brentuximab vedotin, cyclophosphamide, doxorubicin, and prednisone (A+CHP) is superior to cyclophosphamide, doxorubicin, vincris
Drug combination for stage IV melanoma shows success in trial

Drug combination for stage IV melanoma shows success in trial

by CU Anschutz Medical CampusMelanoma. Credit: Wikimedia Commons/National Cancer InstituteA new multidrug treatment for patients with stage IV melanoma has proven effective after a three-year cli

Drug combination for stage IV melanoma shows success in trial

by CU Anschutz Medical CampusMelanoma. Credit: Wikimedia Commons/National Cancer InstituteA new multidrug treatment for patients with stage IV melanoma has proven effective after a three-year cli