Team successfully generates mouse models for two subtypes of multiple myeloma

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineLeft: Normal bone marrow in the control animals with stained myeloid cells. Right: Bone marrow in the transgenic animals with pl

Updated on: January 07,2024

Team successfully generates mouse models for two subtypes of multiple myeloma

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineLeft: Normal bone marrow in the control animals with stained myeloid cells. Right: Bone marrow in the transgenic animals with pl

Updated on:January 07,2024

A way to prevent pancreatic cancer from spreading post-surgery?

by Cold Spring Harbor LaboratoryOn the left is a section of a pancreatic cancer patient's primary tumor, with cancer cells (red) and CK19, a marker of proliferation (green), evident. On the r

Updated on: May 05,2024

A way to prevent pancreatic cancer from spreading post-surgery?

by Cold Spring Harbor LaboratoryOn the left is a section of a pancreatic cancer patient's primary tumor, with cancer cells (red) and CK19, a marker of proliferation (green), evident. On the r

Updated on:May 05,2024

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the

Updated on: February 20,2024

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the

Updated on:February 20,2024

Hormone therapy for breast cancer linked with lower dementia risk

byUniversity of PittsburghCredit: CC0 Public DomainHormone modulating therapy (HMT) used for the treatment of breast cancer was associated with a 7% lower risk of developing Alzheimer's dise

Updated on: July 17,2024

Hormone therapy for breast cancer linked with lower dementia risk

byUniversity of PittsburghCredit: CC0 Public DomainHormone modulating therapy (HMT) used for the treatment of breast cancer was associated with a 7% lower risk of developing Alzheimer's dise

Updated on:July 17,2024

Attacking metastatic prostate cancer early with combination treatment approach improves outcomes in preliminary study

by Denise Heady,University of California, Los AngelesProstate cancer cells. Credit: NIH Image GalleryA team of UCLA Health Jonsson Comprehensive Cancer Center investigators has shown the combina

Updated on: March 30,2024

Attacking metastatic prostate cancer early with combination treatment approach improves outcomes in preliminary study

by Denise Heady,University of California, Los AngelesProstate cancer cells. Credit: NIH Image GalleryA team of UCLA Health Jonsson Comprehensive Cancer Center investigators has shown the combina

Updated on:March 30,2024

Specific sequence of drugs reduces cost of treating metastatic breast cancer while preserving quality of life

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainGiving standard chemotherapy drugs in a specific sequence for some types of metastatic breast cancer can help reduce

Updated on: January 07,2024

Specific sequence of drugs reduces cost of treating metastatic breast cancer while preserving quality of life

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainGiving standard chemotherapy drugs in a specific sequence for some types of metastatic breast cancer can help reduce

Updated on:January 07,2024

Study pinpoints what causes relapse after cancer immunotherapy

by Elaine Fuchs,Rockefeller UniversityKiller T cells surround a cancer cell. Credit: NIHHarnessing the body's immune system to fight off cancer, a tactic known as immunotherapy, has tremendo

Updated on: May 25,2024

Study pinpoints what causes relapse after cancer immunotherapy

by Elaine Fuchs,Rockefeller UniversityKiller T cells surround a cancer cell. Credit: NIHHarnessing the body's immune system to fight off cancer, a tactic known as immunotherapy, has tremendo

Updated on:May 25,2024

Examining the pesticides that may increase cancer risk in children

by Anna Novoselov,University of California, Los AngelesEstimated Odds Ratios and 95% Confidence Intervals from the Hierarchical Logistic Regression Model for all cases combined. Credit:Int

Updated on: February 03,2024

Examining the pesticides that may increase cancer risk in children

by Anna Novoselov,University of California, Los AngelesEstimated Odds Ratios and 95% Confidence Intervals from the Hierarchical Logistic Regression Model for all cases combined. Credit:Int

Updated on:February 03,2024

Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m

Updated on: January 07,2024

Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m

Updated on:January 07,2024

Head and neck cancer: Identifying markers to facilitate better treatment in the future

byMedical University of ViennaCredit: AI-generated imageMalignant tumors in the head and neck region are very heterogeneous and therefore difficult to treat. In addition, the lack of prognostic

Updated on: January 07,2024

Head and neck cancer: Identifying markers to facilitate better treatment in the future

byMedical University of ViennaCredit: AI-generated imageMalignant tumors in the head and neck region are very heterogeneous and therefore difficult to treat. In addition, the lack of prognostic

Updated on:January 07,2024

Study identifies new therapeutic target for tumor treatment

by Olivia Dimmer,Northwestern UniversityIntratumoral Tregcells have increased mRNA expression ofUsp22andUsp21.(AtoC) mRNA level of YFP+sorted Treg

Updated on: February 03,2024

Study identifies new therapeutic target for tumor treatment

by Olivia Dimmer,Northwestern UniversityIntratumoral Tregcells have increased mRNA expression ofUsp22andUsp21.(AtoC) mRNA level of YFP+sorted Treg

Updated on:February 03,2024

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on: February 18,2024

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on:February 18,2024