Balance of 'stop' and 'go' signaling could be key to cancer immunotherapy response

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainA crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by ca

Updated on: March 14,2024 10

Balance of 'stop' and 'go' signaling could be key to cancer immunotherapy response

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainA crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by ca

Updated on:March 14,2024 10

New insights into liver cancer using organoids

by Princess Máxima Center for Pediatric OncologyA culture of mini livers. Credit: Benedetta Artegiani / Princess Máxima Center for pediatric oncologyScientists of the Princess Máxima Center for pediat

Updated on: February 24,2024 14

New insights into liver cancer using organoids

by Princess Máxima Center for Pediatric OncologyA culture of mini livers. Credit: Benedetta Artegiani / Princess Máxima Center for pediatric oncologyScientists of the Princess Máxima Center for pediat

Updated on:February 24,2024 14

New study shows increased cancer mortality in people with type 2 diabetes

byDiabetologiaCredit: Pixabay/CC0 Public DomainNew research published inDiabetologiashows that cancer mortality in people with type 2 diabetes is substantially higher than in the gen

Updated on: January 12,2024 10

New study shows increased cancer mortality in people with type 2 diabetes

byDiabetologiaCredit: Pixabay/CC0 Public DomainNew research published inDiabetologiashows that cancer mortality in people with type 2 diabetes is substantially higher than in the gen

Updated on:January 12,2024 10

Global disease burden related to nonmelanoma skin cancer explored

The disease burden attributable to nonmelanoma skin cancer (NMSC) is considerable and expected to continue increasing, according to a study published online July 30 inBMC Cancer.Wan Hu, from Anh

Updated on: January 07,2024 9

Global disease burden related to nonmelanoma skin cancer explored

The disease burden attributable to nonmelanoma skin cancer (NMSC) is considerable and expected to continue increasing, according to a study published online July 30 inBMC Cancer.Wan Hu, from Anh

Updated on:January 07,2024 9

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on: February 01,2024 19

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on:February 01,2024 19

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on: March 25,2024 6

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on:March 25,2024 6

'Bone in a dish' opens new window on cancer initiation, metastasis, bone healing

by Oregon Health & Science UniversityLuiz Bertassoni D.D.S., Ph.D., and Avathamsa Athirasala, M.Sc.Eng., inspect the 3D mineral structure populated with living cells, providing a unique model

Updated on: March 13,2024 16

'Bone in a dish' opens new window on cancer initiation, metastasis, bone healing

by Oregon Health & Science UniversityLuiz Bertassoni D.D.S., Ph.D., and Avathamsa Athirasala, M.Sc.Eng., inspect the 3D mineral structure populated with living cells, providing a unique model

Updated on:March 13,2024 16

Study hints at how cancer immunotherapy can be safer

by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainCancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumor

Updated on: February 03,2024 10

Study hints at how cancer immunotherapy can be safer

by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainCancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumor

Updated on:February 03,2024 10

Researchers report results in rare gynecologic cancers from DART immunotherapy trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of pat

Updated on: February 03,2024 18

Researchers report results in rare gynecologic cancers from DART immunotherapy trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of pat

Updated on:February 03,2024 18

Two-stage transplantation is a viable treatment option for liver metastases, shows study

by Uta von der Gönna, Universitätsklinikum JenaSurgical procedure: At first, only a lobe of the liver with metastases (1) is removed (2) and replaced with a healthy partial organ. Reduced blood flow t

Updated on: January 16,2024 19

Two-stage transplantation is a viable treatment option for liver metastases, shows study

by Uta von der Gönna, Universitätsklinikum JenaSurgical procedure: At first, only a lobe of the liver with metastases (1) is removed (2) and replaced with a healthy partial organ. Reduced blood flow t

Updated on:January 16,2024 19

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the

Updated on: January 11,2024 10

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the

Updated on:January 11,2024 10

New tool charts differentiation landscape of acute myeloid leukemia

by Center for Genomic RegulationGraphical Abstract. Credit:Cell Stem Cell(2023). DOI: 10.1016/j.stem.2023.04.001Researchers have developed a new method to distinguish between cancerous and

Updated on: January 13,2024 13

New tool charts differentiation landscape of acute myeloid leukemia

by Center for Genomic RegulationGraphical Abstract. Credit:Cell Stem Cell(2023). DOI: 10.1016/j.stem.2023.04.001Researchers have developed a new method to distinguish between cancerous and

Updated on:January 13,2024 13