Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on: January 07,2024 9

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on:January 07,2024 9

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on: January 23,2024 18

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on:January 23,2024 18

A new tool to screen drugs that target loss of tumor suppressor genes

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104437In a May publication iniScience, researchers led by Ludwig Johns Hopkins's

Updated on: January 30,2024 11

A new tool to screen drugs that target loss of tumor suppressor genes

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104437In a May publication iniScience, researchers led by Ludwig Johns Hopkins's

Updated on:January 30,2024 11

Study outlines opportunities to achieve Cancer Moonshot goal of reducing cancer death rates

by National Institutes of HealthTo achieve the Cancer Moonshot goal, cancer death rates must decline faster. Credit: Shiels M, et al.Cancer Discovery, 2023Researchers from the National Inst

Updated on: February 18,2024 13

Study outlines opportunities to achieve Cancer Moonshot goal of reducing cancer death rates

by National Institutes of HealthTo achieve the Cancer Moonshot goal, cancer death rates must decline faster. Credit: Shiels M, et al.Cancer Discovery, 2023Researchers from the National Inst

Updated on:February 18,2024 13

Changes in RECIST tumor measures correlate linearly with survival in patients treated with checkpoint inhibitors

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainThe Response Evaluation Criteria In Solid Tumors (RECIST), used in many clinical trials to evaluate changes in tumor burden over time, c

Updated on: January 28,2024 10

Changes in RECIST tumor measures correlate linearly with survival in patients treated with checkpoint inhibitors

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainThe Response Evaluation Criteria In Solid Tumors (RECIST), used in many clinical trials to evaluate changes in tumor burden over time, c

Updated on:January 28,2024 10

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the

Updated on: January 11,2024 10

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the

Updated on:January 11,2024 10

New CAR T-cell therapy research shows potential in solid tumors

by Peter MacCallum Cancer CenterCredit: Peter MacCallum Cancer CenterPeter Mac researchers have developed a new approach to chimeric antigen receptor (CAR) T-cell therapy which has proven effective in

Updated on: January 11,2024 12

New CAR T-cell therapy research shows potential in solid tumors

by Peter MacCallum Cancer CenterCredit: Peter MacCallum Cancer CenterPeter Mac researchers have developed a new approach to chimeric antigen receptor (CAR) T-cell therapy which has proven effective in

Updated on:January 11,2024 12

Radiation before mastectomy found to cut time delays for reconstructive surgery in breast cancer patients

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at The University of Texas MD Anderson Cancer Center showed that altering the sequence of breast c

Updated on: April 06,2024 0

Radiation before mastectomy found to cut time delays for reconstructive surgery in breast cancer patients

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at The University of Texas MD Anderson Cancer Center showed that altering the sequence of breast c

Updated on:April 06,2024 0

Study explores how antifragility in complex dynamical systems could revolutionize cancer treatment

byH. Lee Moffitt Cancer Center & Research InstituteAntifragility-associated terms, defined for technical and natural (biological) systems. Credit:npj Complexity(2024). DOI: 10.10

Updated on: August 26,2024 0

Study explores how antifragility in complex dynamical systems could revolutionize cancer treatment

byH. Lee Moffitt Cancer Center & Research InstituteAntifragility-associated terms, defined for technical and natural (biological) systems. Credit:npj Complexity(2024). DOI: 10.10

Updated on:August 26,2024 0

CAR T-cell therapy proves effective in first trial in patients with resistant multiple myeloma

by Roswell Park Comprehensive Cancer CenterCredit: CC0 Public DomainA therapy made of immune system T cells engineered to target a somewhat enigmatic cell protein called GPRC5D antigen produced impres

Updated on: April 09,2024 13

CAR T-cell therapy proves effective in first trial in patients with resistant multiple myeloma

by Roswell Park Comprehensive Cancer CenterCredit: CC0 Public DomainA therapy made of immune system T cells engineered to target a somewhat enigmatic cell protein called GPRC5D antigen produced impres

Updated on:April 09,2024 13

Tumor microbiome linked to immunotherapy success in sarcoma patients

by Stephanie Winn,UC DavisSoft tissue sarcomas intratumoral microbiome at diagnosis may link with prognosis. (A) Representative gross examination of extremity synovial sarcoma specimen; asterisk

Updated on: January 22,2024 10

Tumor microbiome linked to immunotherapy success in sarcoma patients

by Stephanie Winn,UC DavisSoft tissue sarcomas intratumoral microbiome at diagnosis may link with prognosis. (A) Representative gross examination of extremity synovial sarcoma specimen; asterisk

Updated on:January 22,2024 10

Treatment decisions in new era of individualized therapy for metastatic hormone-sensitive prostate cancer

byDana-Farber Cancer InstituteProstate cancer cells. Credit: NIH Image GalleryOncologists have traditionally prescribed androgen deprivation therapy (ADT) alone for patients with metastatic horm

Updated on: January 22,2024 13

Treatment decisions in new era of individualized therapy for metastatic hormone-sensitive prostate cancer

byDana-Farber Cancer InstituteProstate cancer cells. Credit: NIH Image GalleryOncologists have traditionally prescribed androgen deprivation therapy (ADT) alone for patients with metastatic horm

Updated on:January 22,2024 13