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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainTreating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians neve

Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainTreating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians neve
Exploring CAR T-cell therapy for aggressive follicular lymphoma

Exploring CAR T-cell therapy for aggressive follicular lymphoma

by Olivia Dimmer,Northwestern UniversityORR by best overall response per IRC assessment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02986-9CAR T-cell therapy is an effecti

Exploring CAR T-cell therapy for aggressive follicular lymphoma

by Olivia Dimmer,Northwestern UniversityORR by best overall response per IRC assessment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02986-9CAR T-cell therapy is an effecti
Study results may lead to improved diagnostics for breast cancer

Study results may lead to improved diagnostics for breast cancer

by WileyThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli, Ph.D., and Ka

Study results may lead to improved diagnostics for breast cancer

by WileyThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli, Ph.D., and Ka
Personalized simulations predict patient outcomes for blood cancer treatment in breakthrough study

Personalized simulations predict patient outcomes for blood cancer treatment in breakthrough study

byUniversity of SussexComputational modeling of the cell cycle and apoptosis reveal limited impact of archetypal double hit mutations on their respective molecular networks. Credit:Blood C

Personalized simulations predict patient outcomes for blood cancer treatment in breakthrough study

byUniversity of SussexComputational modeling of the cell cycle and apoptosis reveal limited impact of archetypal double hit mutations on their respective molecular networks. Credit:Blood C
Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part
Researchers map the genome of testicular cancer

Researchers map the genome of testicular cancer

by Laura Oleniacz,UNC Lineberger Comprehensive Cancer CenterUNC Lineberger's Katherine Hoadley, PhD. Credit: UNC Lineberger Comprehensive Cancer CenterTesticular germ cell cancer, a disease

Researchers map the genome of testicular cancer

by Laura Oleniacz,UNC Lineberger Comprehensive Cancer CenterUNC Lineberger's Katherine Hoadley, PhD. Credit: UNC Lineberger Comprehensive Cancer CenterTesticular germ cell cancer, a disease
Ophthalmologic manifestations of acute leukemia are heterogeneous

Ophthalmologic manifestations of acute leukemia are heterogeneous

by Elana GotkineOphthalmologic manifestations of acute leukemia are heterogeneous and detectable at initial presentation or relapse, according to a studypublishedonline July 10 in the&nbsp

Ophthalmologic manifestations of acute leukemia are heterogeneous

by Elana GotkineOphthalmologic manifestations of acute leukemia are heterogeneous and detectable at initial presentation or relapse, according to a studypublishedonline July 10 in the&nbsp
Researchers identify new way to make cancer self-destruct

Researchers identify new way to make cancer self-destruct

by Perelman School of Medicine at the University of PennsylvaniaATF4 is at a point after both pathways come back together. Credit: Penn MedicineFor years, researchers have been trying to target a

Researchers identify new way to make cancer self-destruct

by Perelman School of Medicine at the University of PennsylvaniaATF4 is at a point after both pathways come back together. Credit: Penn MedicineFor years, researchers have been trying to target a
Targeting ABC transporters in pancreatic ductal carcinoma—past, present, or future?

Targeting ABC transporters in pancreatic ductal carcinoma—past, present, or future?

by Impact Journals LLCRole for ABCB1 in PDAC chemoresistance. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28597A new editorial paper titled "Targeting ABC transporters in PDAC—p

Targeting ABC transporters in pancreatic ductal carcinoma—past, present, or future?

by Impact Journals LLCRole for ABCB1 in PDAC chemoresistance. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28597A new editorial paper titled "Targeting ABC transporters in PDAC—p
Researchers discover the Achilles' heel of an aggressive brain cancer

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen
Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne