Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome

by Mass General BrighamSecondary mutations in the PI3K/AKT pathway emerge during treatment with inavolisib and lead to acquired resistance. A-B, Droplet digital PCR analysis of serial ctDNA sampl

Updated on: June 24,2024

Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome

by Mass General BrighamSecondary mutations in the PI3K/AKT pathway emerge during treatment with inavolisib and lead to acquired resistance. A-B, Droplet digital PCR analysis of serial ctDNA sampl

Updated on:June 24,2024

Researchers discover incredible HULLK that controls prostate cancer progression

by University of Virginia Health SystemDan Gioeli, Ph.D., of the University of Virginia School of Medicine, has identified a key to controlling the growth and progression of prostate cancer, the secon

Updated on: June 19,2024

Researchers discover incredible HULLK that controls prostate cancer progression

by University of Virginia Health SystemDan Gioeli, Ph.D., of the University of Virginia School of Medicine, has identified a key to controlling the growth and progression of prostate cancer, the secon

Updated on:June 19,2024

Rucaparib efficacious in metastatic castration-resistant prostate cancer

by Elana GotkineFor patients with metastatic castration-resistant prostate cancer, treatment with rucaparib is associated with significantly longer duration of imaging-based progression-free survival

Updated on: December 28,2023

Rucaparib efficacious in metastatic castration-resistant prostate cancer

by Elana GotkineFor patients with metastatic castration-resistant prostate cancer, treatment with rucaparib is associated with significantly longer duration of imaging-based progression-free survival

Updated on:December 28,2023

New model shows potential for human papillomavirus vaccination switch to 1-dose gender-neutral approach

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainCanadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and

Updated on: November 11,2024

New model shows potential for human papillomavirus vaccination switch to 1-dose gender-neutral approach

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainCanadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and

Updated on:November 11,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on: January 08,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on:January 08,2024

Research reveals new possibilities to improve treatment of endometrial carcinoma

by Ana María Rodríguez,Baylor College of MedicineCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.007Endometrial carcinoma, a cancer of the lining of the uterus, is the most co

Updated on: July 02,2024

Research reveals new possibilities to improve treatment of endometrial carcinoma

by Ana María Rodríguez,Baylor College of MedicineCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.007Endometrial carcinoma, a cancer of the lining of the uterus, is the most co

Updated on:July 02,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on: August 27,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on:August 27,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Researchers develop an algorithm to improve cancer treatment

by Josh Barney,University of VirginiaOverview of KSTAR algorithm. First, we heuristically prune dense and highly overlapping weighted kinase-substrate prediction graphs from NetworKIN into many

Updated on: February 18,2024

Researchers develop an algorithm to improve cancer treatment

by Josh Barney,University of VirginiaOverview of KSTAR algorithm. First, we heuristically prune dense and highly overlapping weighted kinase-substrate prediction graphs from NetworKIN into many

Updated on:February 18,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on: March 30,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on:March 30,2024

Mathematical modeling leads to a better understanding of prostate cancer

by Eva Schissler,University of CologneCredit:Cell Systems(2024). DOI: 10.1016/j.cels.2024.10.005A team led by Dr. Yuri Tolkach at the University of Cologne's Faculty of Medicine

Updated on: December 01,2024

Mathematical modeling leads to a better understanding of prostate cancer

by Eva Schissler,University of CologneCredit:Cell Systems(2024). DOI: 10.1016/j.cels.2024.10.005A team led by Dr. Yuri Tolkach at the University of Cologne's Faculty of Medicine

Updated on:December 01,2024

Examining a potential second generation epigenetic therapy for advanced solid tumors

by Vall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPreliminary results of a first-in-human study show manageable toxicity and preliminary antitumor activity of a potential sec

Updated on: February 18,2024

Examining a potential second generation epigenetic therapy for advanced solid tumors

by Vall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPreliminary results of a first-in-human study show manageable toxicity and preliminary antitumor activity of a potential sec

Updated on:February 18,2024