First-in-class targeted microRNA therapy slows cancer tumor growth

by Purdue UniversityA new therapy targets cancer cells with a modified strand of micro-RNA that naturally blocks cell division. Credit: Second Bay Studios/Purdue UniversityA new cancer therapy de

Updated on: February 18,2024

First-in-class targeted microRNA therapy slows cancer tumor growth

by Purdue UniversityA new therapy targets cancer cells with a modified strand of micro-RNA that naturally blocks cell division. Credit: Second Bay Studios/Purdue UniversityA new cancer therapy de

Updated on:February 18,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on: May 07,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on:May 07,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on: March 12,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on:March 12,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on: February 24,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on:February 24,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on: January 12,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on:January 12,2024

Trial finds adding immunotherapy to neoadjuvant chemoradiation may improve outcomes in esophageal cancer

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA studypublishedinClinical Cancer Researchfound that in patients with unresectable, locally advanced

Updated on: November 30,2024

Trial finds adding immunotherapy to neoadjuvant chemoradiation may improve outcomes in esophageal cancer

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA studypublishedinClinical Cancer Researchfound that in patients with unresectable, locally advanced

Updated on:November 30,2024

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on: January 30,2024

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on:January 30,2024

Immunotherapy in first-line standard therapy significantly improves survival in metastatic or recurrent cervical cancer

byVall d'Hebron Institute of OncologyCredit: CC0 Public DomainPublished inThe Lancet, results of the randomized phase III BEATcc academic trial (ENGOT-Cx10/GEICO 68-C/JGOG1084/GOG-3030

Updated on: January 26,2024

Immunotherapy in first-line standard therapy significantly improves survival in metastatic or recurrent cervical cancer

byVall d'Hebron Institute of OncologyCredit: CC0 Public DomainPublished inThe Lancet, results of the randomized phase III BEATcc academic trial (ENGOT-Cx10/GEICO 68-C/JGOG1084/GOG-3030

Updated on:January 26,2024

Novel drug combination shows promise for advanced HER2-negative breast cancer

by Johns Hopkins University School of MedicineClinical efficacy.a–c, Responses as shown by a waterfall plot (a), swimmers plot (b) and spider plot (c). The dashed lines correspond to +20% a

Updated on: May 09,2024

Novel drug combination shows promise for advanced HER2-negative breast cancer

by Johns Hopkins University School of MedicineClinical efficacy.a–c, Responses as shown by a waterfall plot (a), swimmers plot (b) and spider plot (c). The dashed lines correspond to +20% a

Updated on:May 09,2024

Wide variation in bowel cancer rates after colonoscopies in England

by British Medical JournalBowel cancer survivor John Barnes. Credit: University of LeedsSubstantial variation exists between colonoscopy providers in rates of bowel cancer up to three years after

Updated on: May 11,2024

Wide variation in bowel cancer rates after colonoscopies in England

by British Medical JournalBowel cancer survivor John Barnes. Credit: University of LeedsSubstantial variation exists between colonoscopy providers in rates of bowel cancer up to three years after

Updated on:May 11,2024

Microbiome provides new clues to determining development of colon cancer

by George Washington UniversityCredit: CC0 Public DomainA mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts

Updated on: May 17,2024

Microbiome provides new clues to determining development of colon cancer

by George Washington UniversityCredit: CC0 Public DomainA mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts

Updated on:May 17,2024

Research suggests commonly used prostate cancer treatment rewires engine of prostate tumors

byUniversity of MichiganIn three of the 21 cases Joshi Alumkal and his team studied, the gene expression of the prostate tumors changed after receiving enzalutamide and no longer had the androge

Updated on: January 16,2024

Research suggests commonly used prostate cancer treatment rewires engine of prostate tumors

byUniversity of MichiganIn three of the 21 cases Joshi Alumkal and his team studied, the gene expression of the prostate tumors changed after receiving enzalutamide and no longer had the androge

Updated on:January 16,2024