Researchers stimulate gene that enhances CAR T-cell treatments for solid tumors

byPeter MacCallum Cancer CentreFOX1-ADA overexpression enhances CAR T cell polyfunctionality. a, Schematic of tumor cell coculture assay. b, IFNγ and TNF production following each round of E0771

Updated on: April 28,2024 0

Researchers stimulate gene that enhances CAR T-cell treatments for solid tumors

byPeter MacCallum Cancer CentreFOX1-ADA overexpression enhances CAR T cell polyfunctionality. a, Schematic of tumor cell coculture assay. b, IFNγ and TNF production following each round of E0771

Updated on:April 28,2024 0

Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

byWileyCredit: CC0 Public DomainBoth acupuncture—which is invasive and involves inserted needles—and acupressure—which is non-invasive and involves mechanical pressure—can potentially help reduc

Updated on: January 15,2024 19

Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

byWileyCredit: CC0 Public DomainBoth acupuncture—which is invasive and involves inserted needles—and acupressure—which is non-invasive and involves mechanical pressure—can potentially help reduc

Updated on:January 15,2024 19

Genetic testing for prostate cancer increases after introduction of point-of-care program

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainSome patients with prostate cancer have genetic mutations that may impact their treatment. A comprehensive, on-site genetic testing progr

Updated on: January 02,2024 5

Genetic testing for prostate cancer increases after introduction of point-of-care program

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainSome patients with prostate cancer have genetic mutations that may impact their treatment. A comprehensive, on-site genetic testing progr

Updated on:January 02,2024 5

Examining a potential second generation epigenetic therapy for advanced solid tumors

by Vall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPreliminary results of a first-in-human study show manageable toxicity and preliminary antitumor activity of a potential sec

Updated on: February 18,2024 13

Examining a potential second generation epigenetic therapy for advanced solid tumors

by Vall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPreliminary results of a first-in-human study show manageable toxicity and preliminary antitumor activity of a potential sec

Updated on:February 18,2024 13

Rogue immune cells linked to leukemia found to be a key driver of autoimmune diseases

by Garvan Institute of Medical ResearchA killer T cell (centre) hunting a target cell. Credit: NIH Image GalleryGene variants associated with leukemia can produce "rogue" immune cells t

Updated on: February 20,2024 11

Rogue immune cells linked to leukemia found to be a key driver of autoimmune diseases

by Garvan Institute of Medical ResearchA killer T cell (centre) hunting a target cell. Credit: NIH Image GalleryGene variants associated with leukemia can produce "rogue" immune cells t

Updated on:February 20,2024 11

Research identifies new way to halt pancreatic cancer invasion by targeting healthy cells

by Queen Mary, University of LondonInhibition of FGFR1 limits invasion in pre-clinical models of PDAC.ARepresentative H&E images of MIA PaCa-2: PS1 organotypics treated with 100 n

Updated on: February 20,2024 14

Research identifies new way to halt pancreatic cancer invasion by targeting healthy cells

by Queen Mary, University of LondonInhibition of FGFR1 limits invasion in pre-clinical models of PDAC.ARepresentative H&E images of MIA PaCa-2: PS1 organotypics treated with 100 n

Updated on:February 20,2024 14

Surge in syphilis cases leads some providers to ration penicillin

by Catherine Sweeney, WPLN, KFF Health NewsCredit: Pixabay/CC0 Public DomainWhen Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was sh

Updated on: May 07,2024 12

Surge in syphilis cases leads some providers to ration penicillin

by Catherine Sweeney, WPLN, KFF Health NewsCredit: Pixabay/CC0 Public DomainWhen Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was sh

Updated on:May 07,2024 12

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat

Updated on: June 01,2024 4

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat

Updated on:June 01,2024 4

Musashi 1 in breast cancer: Implications for dormancy and survival in bone marrow

by Impact Journals LLCKey summary of findings. Shown is increased expression of PD-L1 and Msi 1 in CSCs. Credit:Aging(2023). DOI: 10.18632/aging.204620A new research paper titled "Inc

Updated on: January 10,2024 10

Musashi 1 in breast cancer: Implications for dormancy and survival in bone marrow

by Impact Journals LLCKey summary of findings. Shown is increased expression of PD-L1 and Msi 1 in CSCs. Credit:Aging(2023). DOI: 10.18632/aging.204620A new research paper titled "Inc

Updated on:January 10,2024 10

New model identifies women at high risk for endometrial cancer

byBrigham and Women's HospitalInclusion and exclusion of study participants from NHS II. Credit:JNCI: Journal of the National Cancer Institute(2023). DOI: 10.1093/jnci/djad014End

Updated on: January 15,2024 10

New model identifies women at high risk for endometrial cancer

byBrigham and Women's HospitalInclusion and exclusion of study participants from NHS II. Credit:JNCI: Journal of the National Cancer Institute(2023). DOI: 10.1093/jnci/djad014End

Updated on:January 15,2024 10

Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer

by University of OttawaMulti-omic characterization of VXN cancer-selective effect on cell functions. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00727-yA new, cutting-edge stu

Updated on: May 11,2024 6

Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer

by University of OttawaMulti-omic characterization of VXN cancer-selective effect on cell functions. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00727-yA new, cutting-edge stu

Updated on:May 11,2024 6

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022

Updated on: January 02,2024 9

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022

Updated on:January 02,2024 9