Identification of colony stimulating factor 1 receptor offers new strategy for cancer immunotherapy

by Zhang Nannan,Chinese Academy of SciencesIHMT-CSF1R-833 alters the macrophage polarization in M2 macrophages derived from RAW264.7 cells by inducing the M1 macrophage phenotype. Credit: Liang

Updated on: December 25,2023

Identification of colony stimulating factor 1 receptor offers new strategy for cancer immunotherapy

by Zhang Nannan,Chinese Academy of SciencesIHMT-CSF1R-833 alters the macrophage polarization in M2 macrophages derived from RAW264.7 cells by inducing the M1 macrophage phenotype. Credit: Liang

Updated on:December 25,2023

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on: December 22,2023

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on:December 22,2023

World-first clinical trial with 'man's best friend' could unlock treatment breakthrough for kids with cancer

by Telethon Kids InstituteThree-year-old Bull Terrier, Maggie, is about to undergo surgery using the immunotherapy gel to treat her sarcoma. It is hoped the world-first clinical trial in dogs will be

Updated on: January 04,2024

World-first clinical trial with 'man's best friend' could unlock treatment breakthrough for kids with cancer

by Telethon Kids InstituteThree-year-old Bull Terrier, Maggie, is about to undergo surgery using the immunotherapy gel to treat her sarcoma. It is hoped the world-first clinical trial in dogs will be

Updated on:January 04,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024

Significant proportion of cancer drugs lack proof of added benefit, finds study

by British Medical JournalCredit: CC0 Public DomainMany cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved

Updated on: May 26,2024

Significant proportion of cancer drugs lack proof of added benefit, finds study

by British Medical JournalCredit: CC0 Public DomainMany cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved

Updated on:May 26,2024

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on: December 22,2023

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on:December 22,2023

Study reveals significant global disparities in cancer care across different countries

byWileyCredit: Pixabay/CC0 Public DomainA recent analysis reveals striking disparities in the cost and availability of cancer drugs across different regions of the globe, with significant gaps b

Updated on: November 30,2024

Study reveals significant global disparities in cancer care across different countries

byWileyCredit: Pixabay/CC0 Public DomainA recent analysis reveals striking disparities in the cost and availability of cancer drugs across different regions of the globe, with significant gaps b

Updated on:November 30,2024

Investigating the most allergen-inducing drugs

by Scientific Project LomonosovComparison of % of spontaneous reports (SRs) with data on drug-induced anaphylaxis (SRsAs) due to a specific pharmacological group among the total SRsAs structure and %

Updated on: May 06,2024

Investigating the most allergen-inducing drugs

by Scientific Project LomonosovComparison of % of spontaneous reports (SRs) with data on drug-induced anaphylaxis (SRsAs) due to a specific pharmacological group among the total SRsAs structure and %

Updated on:May 06,2024

Mediterranean diet improves immunotherapy response rates and progression-free survival in advanced melanoma

by United European GastroenterologyCredit: Unsplash/CC0 Public DomainEating a Mediterranean diet rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunoth

Updated on: December 20,2023

Mediterranean diet improves immunotherapy response rates and progression-free survival in advanced melanoma

by United European GastroenterologyCredit: Unsplash/CC0 Public DomainEating a Mediterranean diet rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunoth

Updated on:December 20,2023

Why do many young cancer survivors forgo human papillomavirus vaccination?

byWileyTEM of papillomavirus. Credit: Public DomainAlthough young cancer survivors face an elevated risk for later developing cervical, oropharyngeal, and several other human papillomavirus (HPV

Updated on: January 08,2024

Why do many young cancer survivors forgo human papillomavirus vaccination?

byWileyTEM of papillomavirus. Credit: Public DomainAlthough young cancer survivors face an elevated risk for later developing cervical, oropharyngeal, and several other human papillomavirus (HPV

Updated on:January 08,2024

Fat fuels aggressive brain cancers

byCardiff UniversityGliobastoma (astrocytoma) WHO grade IV—MRI coronal view, post contrast. 15 year old boy. Credit: Christaras A/ Wikipedia.Fat is powering tumour growth in brain cancer, finds

Updated on: December 18,2023

Fat fuels aggressive brain cancers

byCardiff UniversityGliobastoma (astrocytoma) WHO grade IV—MRI coronal view, post contrast. 15 year old boy. Credit: Christaras A/ Wikipedia.Fat is powering tumour growth in brain cancer, finds

Updated on:December 18,2023

Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice

byThe Spanish National Cancer Research CentreSection of a mouse invasive mesothelioma tumour. Credit: CNIOExposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggr

Updated on: December 22,2023

Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice

byThe Spanish National Cancer Research CentreSection of a mouse invasive mesothelioma tumour. Credit: CNIOExposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggr

Updated on:December 22,2023