New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on: December 25,2023

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on:December 25,2023

Here's why some high-risk patients aren't getting drugs to combat COVID

by Emily Alpert Reyes, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs the toll from the COVID-19 pandemic continued to mount, antiviral medications such as Paxlovid were hailed by health offici

Updated on: May 26,2024

Here's why some high-risk patients aren't getting drugs to combat COVID

by Emily Alpert Reyes, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs the toll from the COVID-19 pandemic continued to mount, antiviral medications such as Paxlovid were hailed by health offici

Updated on:May 26,2024

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on: December 22,2023

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on:December 22,2023

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment

Updated on: January 30,2024

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment

Updated on:January 30,2024

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on: January 10,2024

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on:January 10,2024

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog

Updated on: April 22,2024

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog

Updated on:April 22,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on: December 22,2023

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on:December 22,2023

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on: December 20,2023

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on:December 20,2023

Study hints at why an aggressive form of brain cancer is hard to treat

by Abbey Bigler,Broad Institute of MIT and HarvardAn illustration representing the cellular states of glioblastoma. Credit: Sébastien PerroudGlioblastoma is an incurable brain cancer that kills

Updated on: June 01,2024

Study hints at why an aggressive form of brain cancer is hard to treat

by Abbey Bigler,Broad Institute of MIT and HarvardAn illustration representing the cellular states of glioblastoma. Credit: Sébastien PerroudGlioblastoma is an incurable brain cancer that kills

Updated on:June 01,2024

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on: December 26,2023

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on:December 26,2023

New form of immunotherapy under investigation for cancer that resists conventional T cell therapies

by Delthia Ricks , Medical XpressAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainMedical investigators are theorizing that a combination of t

Updated on: January 25,2024

New form of immunotherapy under investigation for cancer that resists conventional T cell therapies

by Delthia Ricks , Medical XpressAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainMedical investigators are theorizing that a combination of t

Updated on:January 25,2024