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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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The molecules behind metastasis

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art
Clinical trial shows significant disease-free survival for patients diagnosed with non-small cell lung cancer

Clinical trial shows significant disease-free survival for patients diagnosed with non-small cell lung cancer

byYale UniversityDFS per investigator assessment. Kaplan-Meier estimates of duration of (A) DFS in patients with stage II-IIIA disease and (B) in the overall population (stage IB-IIIA) by sevent

Clinical trial shows significant disease-free survival for patients diagnosed with non-small cell lung cancer

byYale UniversityDFS per investigator assessment. Kaplan-Meier estimates of duration of (A) DFS in patients with stage II-IIIA disease and (B) in the overall population (stage IB-IIIA) by sevent
Therapeutic viruses help turbocharge the immune system against cancer

Therapeutic viruses help turbocharge the immune system against cancer

by Richard Harth,Arizona State UniversityThe illustration shows a cancer cell (center) surrounded by immune T-cells augmented with an oncolytic (cancer-fighting) virus. A new study describes how

Therapeutic viruses help turbocharge the immune system against cancer

by Richard Harth,Arizona State UniversityThe illustration shows a cancer cell (center) surrounded by immune T-cells augmented with an oncolytic (cancer-fighting) virus. A new study describes how
Boosting immunotherapy in non-responsive cancer cells

Boosting immunotherapy in non-responsive cancer cells

by Surabhi Chandra,Indian Institute of ScienceAvik Chattopadhyay working in the lab. Credit: Nikita RamtekeCancer immunotherapy primes a patient's immune system to better find and destroy ca

Boosting immunotherapy in non-responsive cancer cells

by Surabhi Chandra,Indian Institute of ScienceAvik Chattopadhyay working in the lab. Credit: Nikita RamtekeCancer immunotherapy primes a patient's immune system to better find and destroy ca
Preoperative immunotherapy for mesothelioma shows favorable outcomes

Preoperative immunotherapy for mesothelioma shows favorable outcomes

by Dipali Pathak,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainIn a study published recently in the journalClinical Cancer Research, researchers at Baylor College of Medicine

Preoperative immunotherapy for mesothelioma shows favorable outcomes

by Dipali Pathak,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainIn a study published recently in the journalClinical Cancer Research, researchers at Baylor College of Medicine
New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc
Lazarus effect in a patient treated with osimertinib for non-small cell lung cancer with leptomeningeal disease

Lazarus effect in a patient treated with osimertinib for non-small cell lung cancer with leptomeningeal disease

by Impact Journals LLCTreatment timeline with chest computed tomography (CT) and brain magnetic resonance images (MRI) on osimertinib. (A) Pretreatment CT chest, demonstrating 18 mm spiculated mass in

Lazarus effect in a patient treated with osimertinib for non-small cell lung cancer with leptomeningeal disease

by Impact Journals LLCTreatment timeline with chest computed tomography (CT) and brain magnetic resonance images (MRI) on osimertinib. (A) Pretreatment CT chest, demonstrating 18 mm spiculated mass in
Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

byH. Lee Moffitt Cancer Center & Research InstituteHemoglobin changes from baseline over time on treatment with magrolimab + azacitidine in patients with HR-MDS (N = 95). Data shown are medi

Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

byH. Lee Moffitt Cancer Center & Research InstituteHemoglobin changes from baseline over time on treatment with magrolimab + azacitidine in patients with HR-MDS (N = 95). Data shown are medi
Researchers target mutation that leads to pancreatic cancer

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le
New bone cancer drug improves survival rates by 50% in preclinical trials

New bone cancer drug improves survival rates by 50% in preclinical trials

byUniversity of East AngliaCredit: Pixabay/CC0 Public DomainResearchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer

New bone cancer drug improves survival rates by 50% in preclinical trials

byUniversity of East AngliaCredit: Pixabay/CC0 Public DomainResearchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer
Trends and hotspots in lung cancer surgery research reviewed over the last decade

Trends and hotspots in lung cancer surgery research reviewed over the last decade

by Health Data ScienceTrends of (a) annual scholarly outputs and (b) average field citation ratios in the world and top five countries in the field of lung cancer surgery, 2012-2021, and association b

Trends and hotspots in lung cancer surgery research reviewed over the last decade

by Health Data ScienceTrends of (a) annual scholarly outputs and (b) average field citation ratios in the world and top five countries in the field of lung cancer surgery, 2012-2021, and association b