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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers find breast cancer protein that could predict chemotherapy sensitivity

Researchers find breast cancer protein that could predict chemotherapy sensitivity

by Hunter Medical Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for

Researchers find breast cancer protein that could predict chemotherapy sensitivity

by Hunter Medical Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for
Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si
Phase I clinical trial of the first drug to successfully inhibit the MYC gene that drives many common cancers

Phase I clinical trial of the first drug to successfully inhibit the MYC gene that drives many common cancers

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainResearchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in

Phase I clinical trial of the first drug to successfully inhibit the MYC gene that drives many common cancers

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainResearchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in
Transistors help identify cancer cell markers

Transistors help identify cancer cell markers

by Tokyo Medical and Dental UniversityIon-sensitive field effect transistors detect breast cancer cells expressing EGFR when bound by an antibody linked to a chemical reporter. Credit: Department of B

Transistors help identify cancer cell markers

by Tokyo Medical and Dental UniversityIon-sensitive field effect transistors detect breast cancer cells expressing EGFR when bound by an antibody linked to a chemical reporter. Credit: Department of B
Genes reveal kidney cancer's risk of recurrence

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:
Long-term study reveals more genetic mutations associated with aggressive prostate cancer

Long-term study reveals more genetic mutations associated with aggressive prostate cancer

byInstitute of Cancer ResearchXenograft model of prostate cancer. Credit: National Institutes of Health, 2015Scientists have added to the list of inherited genetic mutations known to increase th

Long-term study reveals more genetic mutations associated with aggressive prostate cancer

byInstitute of Cancer ResearchXenograft model of prostate cancer. Credit: National Institutes of Health, 2015Scientists have added to the list of inherited genetic mutations known to increase th
'Olive oil' drug shows early promise for some brain cancer patients

'Olive oil' drug shows early promise for some brain cancer patients

by Institute of Cancer ResearchMechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important li

'Olive oil' drug shows early promise for some brain cancer patients

by Institute of Cancer ResearchMechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important li
Exploiting the synergy of nutraceuticals for cancer prevention and treatment

Exploiting the synergy of nutraceuticals for cancer prevention and treatment

by Cactus CommunicationsResearchers from Tata Memorial Centre, India, demonstrate how a resveratrol-copper mix inactivates cell-free chromatic particles to ameliorate a host of pathologies, including

Exploiting the synergy of nutraceuticals for cancer prevention and treatment

by Cactus CommunicationsResearchers from Tata Memorial Centre, India, demonstrate how a resveratrol-copper mix inactivates cell-free chromatic particles to ameliorate a host of pathologies, including
Jumping genes for early detection of gastric cancer

Jumping genes for early detection of gastric cancer

by Braulio Valdebenito-MaturanaExample of a transposable element following cancer development on spatially resolved data. In green the normal epithelium, in brown the serrated lesion, and in red the t

Jumping genes for early detection of gastric cancer

by Braulio Valdebenito-MaturanaExample of a transposable element following cancer development on spatially resolved data. In green the normal epithelium, in brown the serrated lesion, and in red the t
New targets in the fight against pancreatic cancer

New targets in the fight against pancreatic cancer

by Tokyo Medical and Dental UniversityTop, SETD1A, directly recruited to the RUVBL1 promoter, enhances RUVBL1 gene expression by increasing H3K4me3 levels in pancreatic cancer cells. Bottom, High co-e

New targets in the fight against pancreatic cancer

by Tokyo Medical and Dental UniversityTop, SETD1A, directly recruited to the RUVBL1 promoter, enhances RUVBL1 gene expression by increasing H3K4me3 levels in pancreatic cancer cells. Bottom, High co-e
Study offers a potential strategy to improve T cell therapy in solid tumors

Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells

Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells