Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024

Key discovery advances fight to reduce breast cancer recurrence

byDuke-NUS Medical SchoolLoss of Gα13 in ER+ breast cancer cells leads to increased cell growth and tumour development, suggesting that Gα13 may suppress tumours in this subtype of cancer. Credi

Updated on: September 06,2024

Key discovery advances fight to reduce breast cancer recurrence

byDuke-NUS Medical SchoolLoss of Gα13 in ER+ breast cancer cells leads to increased cell growth and tumour development, suggesting that Gα13 may suppress tumours in this subtype of cancer. Credi

Updated on:September 06,2024

Why are so many Australians taking antidepressants?

by Jon Jureidini,The ConversationCredit: Pixabay/CC0 Public DomainAroundone in seven Australianstake antidepressants; more than3.5 millionof us had them dispensed in 2021

Updated on: May 07,2024

Why are so many Australians taking antidepressants?

by Jon Jureidini,The ConversationCredit: Pixabay/CC0 Public DomainAroundone in seven Australianstake antidepressants; more than3.5 millionof us had them dispensed in 2021

Updated on:May 07,2024

Novel treatment regimen for FLT3-mutated acute myeloid leukemia shows promise in new study

by Roswell Park Comprehensive Cancer CenterAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainUp to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene

Updated on: March 22,2024

Novel treatment regimen for FLT3-mutated acute myeloid leukemia shows promise in new study

by Roswell Park Comprehensive Cancer CenterAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainUp to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene

Updated on:March 22,2024

Two genes slow down the development of intestinal tumors

byThe Francis Crick InstituteImage of two intestinaltumours, one a control (top) and one with the genes NEDD4 and NEDD4L deleted (bottom). Credit: The Francis Crick InstituteBenign i

Updated on: December 22,2023

Two genes slow down the development of intestinal tumors

byThe Francis Crick InstituteImage of two intestinaltumours, one a control (top) and one with the genes NEDD4 and NEDD4L deleted (bottom). Credit: The Francis Crick InstituteBenign i

Updated on:December 22,2023

Variants in BRCA1/2 and MMR genes in children with cancer

by Stefan Zorn, Medizinische Hochschule HannoverProfessor Dr. Christian Kratz, initiator of the international study that investigated the cancer risk of disease-relevant variants in BRCA1/2 and MMR ge

Updated on: December 18,2023

Variants in BRCA1/2 and MMR genes in children with cancer

by Stefan Zorn, Medizinische Hochschule HannoverProfessor Dr. Christian Kratz, initiator of the international study that investigated the cancer risk of disease-relevant variants in BRCA1/2 and MMR ge

Updated on:December 18,2023

Development and application of competing risks and multi-state models in cancer epidemiology

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCompeting risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be u

Updated on: December 18,2023

Development and application of competing risks and multi-state models in cancer epidemiology

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCompeting risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be u

Updated on:December 18,2023

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on: March 22,2024

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on:March 22,2024

Denosumab linked to severe hypocalcemia in dialysis-dependent seniors

by Elana GotkineFor female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, accor

Updated on: March 26,2024

Denosumab linked to severe hypocalcemia in dialysis-dependent seniors

by Elana GotkineFor female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, accor

Updated on:March 26,2024

Patient-reported outcomes predict aromatase inhibitor adherence

by SWOGCredit: CC0 Public DomainIf you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients co

Updated on: December 22,2023

Patient-reported outcomes predict aromatase inhibitor adherence

by SWOGCredit: CC0 Public DomainIf you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients co

Updated on:December 22,2023

Resistance (exercise) is far from futile: The unheralded benefits of weight training

by Stuart Phillips,The ConversationCredit: CC0 Public DomainEveryone can agree that exercise is healthy. Among its many benefits, exercise improves heart and brain function, aids in controlling

Updated on: March 26,2024

Resistance (exercise) is far from futile: The unheralded benefits of weight training

by Stuart Phillips,The ConversationCredit: CC0 Public DomainEveryone can agree that exercise is healthy. Among its many benefits, exercise improves heart and brain function, aids in controlling

Updated on:March 26,2024

Breast cancer risk from menopause hormones may last decades

by Marilynn MarchioneIn this May 6, 2010 file photo, a radiologist checks mammograms in in Los Angeles. Women who use certain types of hormones after menopause still have an increased risk of developi

Updated on: December 22,2023

Breast cancer risk from menopause hormones may last decades

by Marilynn MarchioneIn this May 6, 2010 file photo, a radiologist checks mammograms in in Los Angeles. Women who use certain types of hormones after menopause still have an increased risk of developi

Updated on:December 22,2023