Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023

COVID-19 antiviral treatment should be taken for longer, says study

by University College LondonViral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) meas

Updated on: May 11,2024

COVID-19 antiviral treatment should be taken for longer, says study

by University College LondonViral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) meas

Updated on:May 11,2024

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on: December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on:December 20,2023

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on: December 18,2023

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on:December 18,2023

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt

Updated on: July 08,2024

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt

Updated on:July 08,2024

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on: December 22,2023

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on:December 22,2023

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on: December 30,2023

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on:December 30,2023

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on: March 14,2024

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on:March 14,2024

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on: December 22,2023

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on:December 22,2023

Viewpoint: FDA needs to ensure that information on dense breast notifications are clear and understandable to all

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainYou are among the women who dutifully gets an annual mammogram. Year after year, the results are "normal." But af

Updated on: December 23,2023

Viewpoint: FDA needs to ensure that information on dense breast notifications are clear and understandable to all

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainYou are among the women who dutifully gets an annual mammogram. Year after year, the results are "normal." But af

Updated on:December 23,2023

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff

Updated on: December 27,2023

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff

Updated on:December 27,2023

Stage and receptor status can indicate a breast cancer survivor's risk of recurrence

Updated on: December 22,2023

Stage and receptor status can indicate a breast cancer survivor's risk of recurrence

Updated on:December 22,2023