Scientists develop powerful AI algorithm to gain new insights into deadly glioblastoma

by Sylvester Comprehensive Cancer CenterThe SPHINKS network for the precision targeting of master kinases in glioblastoma. Credit: Antonio Iavarone, M.D.Scientists at Sylvester Comprehensive Cancer Ce

Updated on: December 27,2023

Scientists develop powerful AI algorithm to gain new insights into deadly glioblastoma

by Sylvester Comprehensive Cancer CenterThe SPHINKS network for the precision targeting of master kinases in glioblastoma. Credit: Antonio Iavarone, M.D.Scientists at Sylvester Comprehensive Cancer Ce

Updated on:December 27,2023

New AI tool predicts risk for chronic pain in cancer patients

by Eric Hamilton,University of FloridaOverview of our transformer-based chronic pain prediction model: Three different data inputs are passed into dedicated encoders to generate a final vector t

Updated on: August 27,2024

New AI tool predicts risk for chronic pain in cancer patients

by Eric Hamilton,University of FloridaOverview of our transformer-based chronic pain prediction model: Three different data inputs are passed into dedicated encoders to generate a final vector t

Updated on:August 27,2024

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on: December 30,2023

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on:December 30,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on: October 24,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on:October 24,2023

Improving drug therapy for relapsed leukemia

by Haleigh Ehmsen,Northwestern UniversityResponse rates in all FLT3mutpatients treated at any dose (n = 56) and in those who did (n = 35) or did not (n = 21) receive prior treatment with a

Updated on: December 22,2023

Improving drug therapy for relapsed leukemia

by Haleigh Ehmsen,Northwestern UniversityResponse rates in all FLT3mutpatients treated at any dose (n = 56) and in those who did (n = 35) or did not (n = 21) receive prior treatment with a

Updated on:December 22,2023

Researchers clarify role of SMYD3 enzyme in prostate cancer progression

by Sarah Hansen,University of Maryland Baltimore CountySMYD3 loss impedes PCa progression.(A) Expression ofSMYD3mRNA from TCGA [GTEX normal (n= 105), TCGA tumor adjacent normal

Updated on: December 26,2023

Researchers clarify role of SMYD3 enzyme in prostate cancer progression

by Sarah Hansen,University of Maryland Baltimore CountySMYD3 loss impedes PCa progression.(A) Expression ofSMYD3mRNA from TCGA [GTEX normal (n= 105), TCGA tumor adjacent normal

Updated on:December 26,2023

Reprogramming cancer cells into immune defenders

by Tove Smeds,Lund UniversityDolly the sheep determined Filipe Pereira’s future career. The choice was between becoming an architect or a scientist, when one of the world’s most extreme examples

Updated on: December 26,2023

Reprogramming cancer cells into immune defenders

by Tove Smeds,Lund UniversityDolly the sheep determined Filipe Pereira’s future career. The choice was between becoming an architect or a scientist, when one of the world’s most extreme examples

Updated on:December 26,2023

Germany's BioNTech plans UK trial of mRNA cancer therapy

Scientists believe mRNA vaccines could be a game-changer against many diseases.German pharmaceutical company BioNTech, which developed a trailblazing COVID-19 vaccine, will trial a cancer treatment in

Updated on: December 20,2023

Germany's BioNTech plans UK trial of mRNA cancer therapy

Scientists believe mRNA vaccines could be a game-changer against many diseases.German pharmaceutical company BioNTech, which developed a trailblazing COVID-19 vaccine, will trial a cancer treatment in

Updated on:December 20,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on: December 22,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on:December 22,2023

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on: December 26,2023

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on:December 26,2023

Cancer biomarker data is not diverse, with implications for immunotherapy patients from underrepresented groups

byCell PressCredit: Pixabay/CC0 Public DomainHigh tumor mutational burden—the number of mutations found inside cancer cells—may not generalize as an accurate biomarker across diverse cancer pati

Updated on: December 18,2023

Cancer biomarker data is not diverse, with implications for immunotherapy patients from underrepresented groups

byCell PressCredit: Pixabay/CC0 Public DomainHigh tumor mutational burden—the number of mutations found inside cancer cells—may not generalize as an accurate biomarker across diverse cancer pati

Updated on:December 18,2023