The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on: April 28,2024

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on:April 28,2024

The Role of Senescent Macrophages in KRAS-Driven Lung Cancer:Insights from Novel p16-FDR Mouse Models and Therapeutic Implications

Updated on: July 27,2024

The Role of Senescent Macrophages in KRAS-Driven Lung Cancer:Insights from Novel p16-FDR Mouse Models and Therapeutic Implications

Updated on:July 27,2024

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on: December 18,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on:December 18,2023

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on: December 19,2023

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on:December 19,2023

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on: April 27,2024

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on:April 27,2024

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on: December 20,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on:December 20,2023

Australian research shows rates of obesity-related cancers quadrupled in a generation

by Cancer CouncilCredit: CC0 Public DomainNew research by the Daffodil Center, a joint venture of Cancer Council NSW and the University of Sydney, shows the rate of obesity-related cancers in Australi

Updated on: December 19,2023

Australian research shows rates of obesity-related cancers quadrupled in a generation

by Cancer CouncilCredit: CC0 Public DomainNew research by the Daffodil Center, a joint venture of Cancer Council NSW and the University of Sydney, shows the rate of obesity-related cancers in Australi

Updated on:December 19,2023

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on: December 21,2023

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on:December 21,2023

Immunotherapy Combo Boosts Survival in Metastatic Melanoma

byColleen Fleisson August 19, 2023For patients diagnosed with advancedmetastatic melanomathat does not respond to the commonly utilized PD-1 inhibitors, immunotherapy drugs ipi

Updated on: December 19,2023

Immunotherapy Combo Boosts Survival in Metastatic Melanoma

byColleen Fleisson August 19, 2023For patients diagnosed with advancedmetastatic melanomathat does not respond to the commonly utilized PD-1 inhibitors, immunotherapy drugs ipi

Updated on:December 19,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on: December 20,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on:December 20,2023

Targeting enzyme could alleviate muscle wasting for cancer patients

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainTargeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially p

Updated on: December 19,2023

Targeting enzyme could alleviate muscle wasting for cancer patients

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainTargeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially p

Updated on:December 19,2023

Skin cancer cells harness nerve cell gene to drill through and invade new tissues

byInstitute of Cancer ResearchMelanoma cell growing into a soft hydrogel. Credit: Professor Chris BakalMelanoma skin cancer cells harness a gene usually used by growing nerves to escape from the

Updated on: December 18,2023

Skin cancer cells harness nerve cell gene to drill through and invade new tissues

byInstitute of Cancer ResearchMelanoma cell growing into a soft hydrogel. Credit: Professor Chris BakalMelanoma skin cancer cells harness a gene usually used by growing nerves to escape from the

Updated on:December 18,2023